AutismKB 2.0

Annotation Detail for SCRN3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SCRN3 ( FLJ23142,MGC149597,SES3 )
Gene Full Name: secernin 3
Band: 2q31.1
Quick LinksEntrez ID:79634; OMIM: NA; Uniprot ID:SCRN3_HUMAN; ENSEMBL ID: ENSG00000144306; HGNC ID: 30382
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of SCRN3 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of SCRN3 mRNAaffects expression 17562736
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of SCRN3 mRNAaffects expression 17484886
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.7110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.4316124888 16192424 16011737 10355542 3786805 15700767 16227642 15721981 16097048 16050911 15673190 18705752
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 4.8116705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.813084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 4.8118788625
MESH:D002386 Cataract Acetaminophen 2.8110977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.066135515
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.6718551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 6.7918551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.7911834606 12540782 16081117 16485898 14986274 15619225 15968718 11529661 16109766 19370779 11461765 16781746 16227642 10663392 16177239 17562736 12705907 14550746 11421492 2444490 10774834 19923254 17522070 12594235 19420014 18713872 19085960 16393943 18071297 11743745 12958197 17906064 12392966 19739265 19416960 10915739 19164858 11287661 11739529 14725611 12153990
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 6.797440962 6884620 10915739 7120509 2869522 16227642 15027814 15968718 21278145 3732212 3786805 15998439 6623471 9327722 10092053 16177239 19085960 11566570 17522070 19336974 7179309 4309450
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.9619426721
MESH:D005234 Fatty Liver Carbon Tetrachloride 3.6515959796 19224547 61145 12631006 16045604 12795759 17595544 16239168
MESH:D005355 Fibrosis Carbon Tetrachloride 4.1018705752
MESH:D005756 Gastritis Acetaminophen 4.5416983495
MESH:D006505 Hepatitis Carbon Tetrachloride 4.1819900420 19110552
MESH:D006930 Hyperalgesia Acetaminophen 3.0616870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 5.2716899240
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.7415338365
MESH:D007674 Kidney Diseases Acetaminophen 2.4215629191 12587719
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.3616705839
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 3.0217157831 11408273 16943688 17174718 16221502 17334410 16239168 11903743 21278145
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 1.7518054572 12632512 17721639 13678700 17944888 12958196 17900296 15338365 17976157 18412020 12667390 16638106 17525996 17805973 12609069 17922224 18481824 18205269 17698563 18210741 18166357 18251166 15876570 18376398 14716833 17761835 16027843 17631135 15052691 15931870 18420326 18277467 17481882 12741479 15959796 14716496 17565644 15123356 18317297 12546737 16097048 17714472 12389079 12586293 18395095 15362042 18429990 16015684 12649538 15730626 18472094 18395914 14620537 18187930 18705752 18472332 20821823 17766677 14512876 17708605 10355542 18339082 16116963 16248980 15057751 15673190 18263696 15996030 18418968 15818738 12445418 12666154 16011737 14748882 12445421 17823541 11481614 17557913 17869086 16192424 15893842 12632514 17640975 12898905 15370692 18006644 18279442 15925388 16033810 15650968 16136751 14724832 18156304
MESH:D008107 Liver Diseases Acetaminophen 4.1911587558 19014921 19784758 12969438 12587719 19460945 16610002 16611625
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.1915720792 16964402 15830285 16246199 17285989
MESH:D017093 Liver Failure Carbon Tetrachloride 4.8215123358
MESH:D017114 Liver Failure, Acute Acetaminophen 10.9416871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 10.9414706259 16899240
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 5.007678174
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 5.0019294768
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 6.772876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 6.7715583823 12014681
MESH:D008546 Melanoma, Experimental Acetaminophen 4.2219513568
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.607678174 18551238
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2618514411
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.8816049721
MESH:D010146 Pain Acetaminophen 2.7716870215
MESH:D012640 Seizures 2,6-dinitrotoluene 2.8218551238
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.4216049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 5.0610091137
MESH:D014581 Urticaria Acetaminophen 3.5010982225
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved