Annotation Detail for ARSJ
Basic Information Top
| Gene Symbol: | ARSJ ( FLJ23548 ) |
|---|---|
| Gene Full Name: | arylsulfatase family, member J |
| Band: | 4q26 |
| Quick Links | Entrez ID:79642; OMIM: 610010; Uniprot ID:ARSJ_HUMAN; ENSEMBL ID: ENSG00000180801; HGNC ID: 26286 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride affects the expression of ARSJ mRNA | affects expression | 17484886 |
| C006253 | pirinixic acid | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ARSJ mRNA | affects binding|increases activity|increases expression | 19710929 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 3.72 | 18653653 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 4.37 | 16434500 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 3.70 | 19483382 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Carbon Tetrachloride | 4.54 | 16124888 16011737 3786805 15721981 10355542 15673190 18705752 16192424 16097048 16227642 15700767 16050911 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Carbon Tetrachloride | 1.86 | 18788625 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 3.19 | 19176532 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 2.61 | 18249437 | |
| MESH:D056486 | Drug-Induced Liver Injury | Carbon Tetrachloride | 2.14 | 10915739 9327722 10092053 4309450 21278145 16227642 15027814 2869522 3786805 7440962 15998439 11566570 6884620 19085960 3732212 15968718 7179309 17522070 6623471 19336974 7120509 16177239 | |
| MESH:D004487 | Edema | pirinixic acid | 3.02 | 12083418 | |
| MESH:D005234 | Fatty Liver | Carbon Tetrachloride | 9.56 | 16045604 16239168 17595544 15959796 19224547 61145 12631006 12795759 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 9.56 | 20131406 19236843 | |
| MESH:D005355 | Fibrosis | Carbon Tetrachloride | 4.22 | 18705752 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 2.81 | 20558911 | |
| MESH:D006505 | Hepatitis | Carbon Tetrachloride | 4.27 | 19900420 19110552 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 3.76 | 18467677 16221962 19772884 19176532 | |
| MESH:D006932 | Hyperbilirubinemia | Carbon Tetrachloride | 5.42 | 16899240 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 3.69 | 20558911 | |
| MESH:D006975 | Hypertension, Portal | Carbon Tetrachloride | 4.85 | 15338365 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 2.93 | 16306350 | |
| MESH:D008103 | Liver Cirrhosis | Carbon Tetrachloride | 3.04 | 17174718 17157831 17334410 16943688 11408273 11903743 21278145 16239168 16221502 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Carbon Tetrachloride | 2.43 | 12445421 18277467 16248980 14512876 16027843 15370692 18395914 12666154 18205269 17823541 18418968 17708605 12632512 14748882 15057751 12389079 18279442 15818738 13678700 17761835 12632514 17698563 12898905 15925388 18339082 14620537 18412020 18006644 18187930 16015684 18429990 18472332 18156304 14716496 18166357 18251166 18317297 18376398 17766677 17714472 12667390 14724832 15362042 15959796 12958196 17869086 16116963 17922224 15876570 18472094 10355542 15650968 16192424 14716833 18705752 18263696 17721639 12649538 17631135 20821823 15123356 18054572 17805973 16011737 15996030 17976157 17640975 11481614 15673190 12609069 12741479 17481882 17565644 15052691 18481824 16097048 17525996 15931870 12586293 16033810 17557913 16136751 18210741 18395095 15730626 17900296 15338365 15893842 12546737 16638106 17944888 18420326 12445418 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 2.43 | 15474484 | |
| MESH:D008107 | Liver Diseases | Carbon Tetrachloride | 2.17 | 17285989 16964402 16246199 15830285 15720792 | |
| MESH:D017093 | Liver Failure | Carbon Tetrachloride | 4.93 | 15123358 | |
| MESH:D017114 | Liver Failure, Acute | Carbon Tetrachloride | 4.20 | 14706259 16899240 | |
| MESH:D008113 | Liver Neoplasms | Carbon Tetrachloride | 4.92 | 19294768 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 4.92 | 16377806 20007298 15890375 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Carbon Tetrachloride | 2.89 | 15583823 12014681 | |
| MESH:D009135 | Muscular Diseases | pirinixic acid | 4.27 | 16239165 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 2.30 | 19151258 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 3.33 | 16411023 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 2.14 | 17405874 | |
| MESH:D009765 | Obesity | pirinixic acid | 1.90 | 20558911 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 2.58 | 19058328 |
| No data |