AutismKB 2.0

Annotation Detail for C3orf52


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:C3orf52 ( FLJ23186,TTMP )
Gene Full Name: chromosome 3 open reading frame 52
Band: 3q13.2
Quick LinksEntrez ID:79669; OMIM: 611956; Uniprot ID:TTMP_HUMAN; ENSEMBL ID: ENSG00000114529; HGNC ID: 26255
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of C3ORF52 proteinaffects expression 20106945
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of C3ORF52 mRNAincreases expression 18687144
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of C3ORF52 mRNAincreases expression 20106945
D016572 Cyclosporine Cyclosporine results in increased expression of C3ORF52 mRNAincreases expression 20106945
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0620464547 20127859
MESH:D000236 Adenoma Benzo(a)pyrene 2.866695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.6419183758
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9917474063 20146248
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 1.9912619106 21507988 12907637
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1320419170
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.7912371664
MESH:D002779 Cholestasis Cyclosporine 3.2119486331
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0816530937
MESH:D005234 Fatty Liver Cyclosporine 3.2819224547
MESH:D005355 Fibrosis Cyclosporine 3.7012639820 12168785
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.858708960
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8320471113
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.0515720958
MESH:D006973 Hypertension Cyclosporine 2.2110903974
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.1615604871
MESH:D007674 Kidney Diseases Cyclosporine 2.548314463 10903974 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0812371664
MESH:D008113 Liver Neoplasms Aflatoxin B1 4.979163691 2125692 15890375 18177683
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.9720195826 21137059
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 2.968603461
MESH:D055370 Lung Injury Asbestos, Crocidolite 4.5817365036
MESH:D008175 Lung Neoplasms Aflatoxin B1 2.5014755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.506695378 17053015 20135361 18520028 18569708 20464547 20869020 18816296 20064080
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.3116166281 16966607 18303189
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.5116801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.5016381670
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3311141357
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.1617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6519348381 18481113
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 5.4510923243
MESH:D011230 Precancerous Conditions Cyclosporine 3.5912371664
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9117292933
MESH:D011565 Psoriasis Cyclosporine 2.3316882103
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 3.1517322281 17365031 17975199 15814490
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5210029692 19755658
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.5620155912 2093021
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.3017053015
MESH:D014605 Uveitis Cyclosporine 4.711336536
MESH:D014985 Xerophthalmia Cyclosporine 5.1617120751
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018