AutismKB 2.0

Annotation Detail for GALNT12


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Basic Information Top
Gene Symbol:GALNT12 ( CRCS1,FLJ21212,GalNAc-T12 )
Gene Full Name: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)
Band: 9q22.33
Quick LinksEntrez ID:79695; OMIM: 610290; Uniprot ID:GLT12_HUMAN; ENSEMBL ID: ENSG00000119514; HGNC ID: 19877
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00512O-Glycan biosynthesis
hsa01100Metabolic pathways
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2053Colon cancer
No data
No data
Desease Name
Colorectal cancer, susceptibility to, 1
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C006632 arsenic trioxide arsenic trioxide results in decreased expression of GALNT12 mRNAdecreases expression 19128835
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of GALNT12 mRNAaffects cotreatment|increases expression 19619570
D004958 Estradiol Estradiol results in increased expression of GALNT12 mRNAincreases expression 19619570
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GALNT12 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of GALNT12 mRNAaffects cotreatment|increases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of GALNT12 mRNAincreases expression 19619570
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GALNT12 mRNAaffects cotreatment|increases expression 17942748
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.4711752688 15322242 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.6617505938
MESH:D000230 Adenocarcinoma arsenic trioxide 7.5111798837 19825857
MESH:D000230 Adenocarcinoma Estradiol 7.5111473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 7.5114692618
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 4.0116835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.3411748828
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.0211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8915885639
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 10.4116206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 10.4112125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.5115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 3.0015746008
MESH:D001943 Breast Neoplasms Estradiol 1.9017289903 18497071 12948864 19861407 16675129 17261762 17018787 14630087
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9020435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.7911589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 5.0916111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 3.1216835633
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 3.1714691202 15073043 16217749 15553829 11135700
MESH:D006528 Carcinoma, Hepatocellular Estradiol 3.1716924424
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.6019014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.5112490120
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.5618670907 16120746 18850075
MESH:D002471 Cell Transformation, Neoplastic Estradiol 3.0318566989
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.5316835633
MESH:D002779 Cholestasis Ethinyl Estradiol 3.1717110522 17681005 11677210 16105132 17333356 15861022 16919318
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.2415340226 8697196 12621046 15668235 16354765
MESH:D015179 Colorectal Neoplasms marker/mechanism
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.4314669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 4.6912609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.5610525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.5610048152 20055451 15322242
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.5615213294
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7417107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.7819279558
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 1.6220420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 3.0511462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.8011000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.6216714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.6912538720
MESH:D016889 Endometrial Neoplasms Estradiol 3.2211473722 18566989 19148513
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.429294722 10568697
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.3812903497
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.3111564622
MESH:D005234 Fatty Liver arsenic trioxide 9.1815073043
MESH:D005234 Fatty Liver Ethinyl Estradiol 9.1815345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 4.0211858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.5120067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.7716904648
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.3210696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.5110048152 11294989
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.7611000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.4515340226 12621046 16120746
MESH:D006558 Herpes Genitalis Estradiol 5.7615709030
MESH:D019584 Hot Flashes Estradiol 4.4717088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.7715340226 16354765 8697196 18606429 16959395
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 2.0218850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 4.3716569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7317937319
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 2.0312878042 12200463
MESH:D007333 Insulin Resistance Estradiol 3.2116627594 16393666
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.7616580747
MESH:D007674 Kidney Diseases Estradiol 2.7815618244
MESH:D007680 Kidney Neoplasms Estradiol 3.3215610895
MESH:D007938 Leukemia arsenic trioxide 3.0015070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.2212560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.9416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.7214633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.1919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1916467208 17050201 19850784 20471514 16968895
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.4616112521 17649720 19075265 16966277 11468182 15748426 17107899 12679006 16823087 19225113 19035177 17869043 9834237 12018890 17712046 16891316 19642359 17217047 12712474 15213294 16331271 15622746 15336539 16330433 11161223
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.8616882451
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 2.3514716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.3512878042
MESH:D008113 Liver Neoplasms arsenic trioxide 4.8514682389
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.8516984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 6.5720377131
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 6.5712151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.6615213294
MESH:D008175 Lung Neoplasms arsenic trioxide 2.3811798837 19825857
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.3811884234 19555203
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.7911807958 17203775 11408345 16891317
MESH:D020149 Manganese Poisoning Estradiol 5.2119453300
MESH:D009101 Multiple Myeloma arsenic trioxide 3.3815949261 11468182 19417148 14977855 19549372
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.4018349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3416105982 16882451
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.3412213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.5916810080
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.4716624393
MESH:D009389 Neovascularization, Pathologic Estradiol 4.3617289903
MESH:D009421 Nervous System Malformations Estradiol 11.2011399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 11.2014600291
MESH:D009436 Neural Tube Defects arsenic trioxide 3.3610525206
MESH:D010051 Ovarian Neoplasms arsenic trioxide 5.1619769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms Estradiol 5.1619401270
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6315580305
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.1511578682
MESH:D010235 Paraganglioma arsenic trioxide 4.6319927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.9712520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 4.0718163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.8211896295 11118676 11399792 11222880
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.3120887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.1419131511
MESH:D011471 Prostatic Neoplasms Estradiol 3.1416740699
MESH:D011537 Pruritus Ethinyl Estradiol 3.9415861022 16919318
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.3518990726
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.4716646077
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.2016192470
MESH:D013088 Spermatocele Ethinyl Estradiol 4.6616709447
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.0811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5215669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.6212697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.3919014326
MESH:D013978 Tibial Fractures Estradiol 5.4119048282
MESH:D016171 Torsades de Pointes arsenic trioxide 4.5915213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 2.6020435036 12845720 11780464 12973940
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8014692618
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.3212125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.9714671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.9715886252
Pathway ID Pathway Name
KEGG:01100 Metabolic pathways
KEGG:00512 Mucin type O-Glycan biosynthesis
Pharmacogenomics Knowledge Base Top
Drug Bank Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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