AutismKB 2.0

Annotation Detail for ZNF768


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Basic Information Top
Gene Symbol:ZNF768 ( FLJ23436 )
Gene Full Name: zinc finger protein 768
Band: 16p11.2
Quick LinksEntrez ID:79724; OMIM: NA; Uniprot ID:ZN768_HUMAN; ENSEMBL ID: ENSG00000169957; HGNC ID: 26273
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of ZNF768 mRNAaffects cotreatment|increases expression 17183730
D012643 Selenium Selenium results in increased expression of ZNF768 mRNAincreases expression 19244175
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of ZNF768 mRNAaffects cotreatment|increases expression 17183730
D014810 Vitamin E Vitamin E results in increased expression of ZNF768 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 4.118875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.3519490988
MESH:D000550 Amblyopia Valproic Acid 5.9617688650
MESH:D001008 Anxiety Disorders Valproic Acid 3.9017497229
MESH:D001321 Autistic Disorder Valproic Acid 1.9817157402 16609825 17688650 19232924 18775368 18177632 18316065 17507914 18558336 18985861 18396377 20603192 19460635 18940202 15238991
MESH:D001714 Bipolar Disorder Valproic Acid 3.2420046352 17594078
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.638888407
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.4916050911
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.8220734317
MESH:D003092 Colitis Selenium 4.3417936198
MESH:D019465 Craniofacial Abnormalities Valproic Acid 2.8017688650 8888407 16575769
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.8019769572
MESH:D056486 Drug-Induced Liver Injury Selenium 4.3115131321
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 4.311733752 19641884
MESH:D004421 Dystonia Valproic Acid 4.511851702
MESH:C538011 Eales disease Vitamin E 5.439068938
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.713659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 4.643922381 16628512
MESH:D004827 Epilepsy Valproic Acid 3.1118234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 3.966426943 6254150 7562514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.867750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.693659116
MESH:D005234 Fatty Liver Valproic Acid 3.7214986274 19224547
MESH:D005315 Fetal Diseases Valproic Acid 5.6116575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.6418558336 8888407
MESH:D006330 Heart Defects, Congenital Vitamin E 3.1716080930
MESH:D006333 Heart Failure Selenium 3.2917162251
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.8116863852 16490937
MESH:D019584 Hot Flashes Vitamin E 4.6914716179
MESH:D006849 Hydrocephalus Valproic Acid 5.5017688650
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 5.1916612254
MESH:D007251 Influenza, Human Selenium 13.5016624496
MESH:D007251 Influenza, Human Vitamin E 13.5016624496
MESH:D007674 Kidney Diseases Vitamin E 3.0012488133
MESH:D007676 Kidney Failure, Chronic Selenium 4.3116518626
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.2016294345 17596541
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 1.9116169303
MESH:D008171 Lung Diseases Vitamin E 3.4316863852
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.9817228818
MESH:D008175 Lung Neoplasms Vitamin E 1.9011062179
MESH:D008325 Mammary Neoplasms, Experimental Selenium 2.9915318939
MESH:D008654 Mesothelioma Selenium 2.9215107826
MESH:D008881 Migraine Disorders Valproic Acid 3.4718803445 18765137
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.458888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3517596541
MESH:D009436 Neural Tube Defects Valproic Acid 3.3716359493 8888407
MESH:D010954 Plasmacytoma Selenium 5.6115087411
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 4.4620603192
MESH:D011471 Prostatic Neoplasms Vitamin E 3.2415084515
MESH:D019310 Pseudolymphoma Valproic Acid 5.2611422049 12752131
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.6419155313
MESH:D012559 Schizophrenia Valproic Acid 2.1015737665 19110320
MESH:D012640 Seizures Valproic Acid 2.9916876388 3137016 14763951 17978042 11738929 11044598 15475178 1511512
MESH:D012871 Skin Diseases Vitamin E 2.5218709164
MESH:D016135 Spinal Dysraphism Valproic Acid 4.0919490988
MESH:D013226 Status Epilepticus Valproic Acid 5.2612833885
MESH:D020521 Stroke Vitamin E 3.8416517955
MESH:D014178 Translocation, Genetic Valproic Acid 5.9617262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 5.153119515
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.208888407
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018