AutismKB 2.0

Annotation Detail for WDR59


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Basic Information Top
Gene Symbol:WDR59 ( FLJ12270,MGC11230 )
Gene Full Name: WD repeat domain 59
Band: 16q23.1
Quick LinksEntrez ID:79726; OMIM: NA; Uniprot ID:WDR59_HUMAN; ENSEMBL ID: ENSG00000103091; HGNC ID: 25706
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of WDR59 mRNAaffects expression 17562736
D014501 Uranium Uranium affects the expression of WDR59 mRNAaffects expression 15672453
C005460 uranyl acetate uranyl acetate affects the expression of WDR59 mRNAaffects expression 15672453
C025643 vinclozolin vinclozolin affects the expression of WDR59 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D001008 Anxiety Disorders vinclozolin 3.9719015723
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.7910977129
MESH:D003456 Cryptorchidism vinclozolin 4.8514966744
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6712540782 19416960 16177239 11461765 12153990 17906064 19085960 18071297 15619225 16781746 16109766 11529661 10774834 11287661 17522070 11743745 19420014 19739265 11421492 12705907 11834606 14725611 16227642 11739529 10663392 10915739 14550746 19923254 16485898 16081117 15968718 17562736 19370779 14986274 12958197 19164858 16393943 12594235 2444490 18713872 12392966
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.5716973722
MESH:D005832 Genital Diseases, Male vinclozolin 6.0216417039
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D007248 Infertility, Male vinclozolin 3.2916467254
MESH:D007674 Kidney Diseases Acetaminophen 2.4015629191 12587719
MESH:D007984 Leydig Cell Tumor vinclozolin 5.3616417039
MESH:D008107 Liver Diseases Acetaminophen 1.7019784758 16611625 19014921 11587558 19460945 12587719 16610002 12969438
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6317185352 16871587
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2118514411
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 4.5319015723 18042343 18220299
MESH:D011469 Prostatic Diseases vinclozolin 5.5718220299
MESH:D011472 Prostatitis vinclozolin 5.5718629315
MESH:D014581 Urticaria Acetaminophen 3.4410982225
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018