AutismKB 2.0

Annotation Detail for CLIP4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CLIP4 ( FLJ21069,FLJ32705,RSNL2 )
Gene Full Name: CAP-GLY domain containing linker protein family, member 4
Band: 2p23.2
Quick LinksEntrez ID:79745; OMIM: NA; Uniprot ID:CLIP4_HUMAN; ENSEMBL ID: ENSG00000115295; HGNC ID: 26108
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CLIP4 mRNAdecreases expression 19150397
D002104 Cadmium Cadmium results in increased expression of CLIP4 mRNAincreases expression 21172416
D016572 Cyclosporine Cyclosporine results in increased expression of CLIP4 mRNAincreases expression 20106945
D002117 Calcitriol Calcitriol results in increased expression of CLIP4 mRNAincreases expression 16002434
D004178 Diquat Diquat results in increased expression of CLIP4 mRNAincreases expression 21172416
D010126 Ozone TTPA protein affects the reaction [Ozone results in increased expression of CLIP4 mRNA]affects reaction|increases expression 19555225
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CLIP4 mRNAincreases expression 19465110
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.2414514962 15322242 11752688
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.7716835633
MESH:D000544 Alzheimer Disease Ozone 2.4815513908
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.2111748828
MESH:D001172 Arthritis, Rheumatoid Ozone 2.6115570426
MESH:D001249 Asthma Ozone 2.7017854713 16373670
MESH:D050197 Atherosclerosis Cadmium 3.7915687053
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.3312125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.2315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.9315746008
MESH:D001943 Breast Neoplasms Calcitriol 2.0811237771
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.0820435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.9015516495 14754758 18417511 19059883 16777450 17626835 18315731
MESH:D002100 Cachexia Ozone 5.1416183385
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 3.0216835633
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 2.6811237771
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.5016120746 18850075 18670907
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 12.3520889678
MESH:D002471 Cell Transformation, Neoplastic Cadmium 12.3517332340
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 12.3512371664
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.4116835633
MESH:D002779 Cholestasis Cyclosporine 3.1219486331
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.2012621046 15668235 15340226 16354765 8697196
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.3117141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2610048152 15322242 20055451
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7217107852
MESH:D056486 Drug-Induced Liver Injury Diquat 4.4818164269 18445702
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 4.4820420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.9611462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.6511000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.3516714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 4.2615138306
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.299294722 10568697
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1320426865
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.2111564622
MESH:D005234 Fatty Liver Cyclosporine 3.1419224547
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.8111858732
MESH:D005355 Fibrosis Cyclosporine 9.7012639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 9.7020067830
MESH:D005756 Gastritis Diquat 6.0215046732
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.628708960
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.0410696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.4610048152 11294989
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.8215720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.6211000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.2516120746 15340226 12621046
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.498697196 16354765 16959395 15340226 18606429
MESH:D006973 Hypertension Cyclosporine 5.2410903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.2418850075 18670907
MESH:D007248 Infertility, Male Diquat 4.464850670
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.9812200463 12878042
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.6216580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.8815604871
MESH:D007674 Kidney Diseases Cadmium 6.7616226777 16962696 16322080
MESH:D007674 Kidney Diseases Cyclosporine 6.7618776723 10903974 8314463
MESH:D007680 Kidney Neoplasms Cyclosporine 2.9712371664
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 1.2412878042
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 1.8016984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.2612151625
MESH:D008171 Lung Diseases Ozone 3.5519066396 8266340
MESH:D055370 Lung Injury Ozone 4.2120417186
MESH:D008175 Lung Neoplasms Ozone 2.447614698 8597069
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.4419555203 11884234
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.2316801185
MESH:D008679 Metaplasia Ozone 5.5510496685
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.2412213967
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.8817954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5318481113 19348381
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.5414600291
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.6912520081
MESH:D016491 Peripheral Vascular Diseases Cadmium 5.7815687053
MESH:D010538 Peritonitis Ozone 4.4916369182
MESH:D011014 Pneumonia Ozone 4.7918007984 18381685 18929643
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.8918163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.4712371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.5911896295 11399792 11118676 11222880
MESH:D011470 Prostatic Hyperplasia Calcitriol 5.1815572423
MESH:D011471 Prostatic Neoplasms Cadmium 3.5917075824
MESH:D011471 Prostatic Neoplasms Calcitriol 3.5915754350 12479363 18247401 16644109 16289102
MESH:D011565 Psoriasis Cyclosporine 2.3016882103
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.1718990726
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.1516192470
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.3512697716
MESH:D014605 Uveitis Cyclosporine 4.431336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.0412125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.6915886252
MESH:D014985 Xerophthalmia Cyclosporine 4.8817120751
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved