AutismKB 2.0

Annotation Detail for MCTP1


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Basic Information Top
Gene Symbol:MCTP1 ( FLJ22344 )
Gene Full Name: multiple C2 domains, transmembrane 1
Band: 5q15
Quick LinksEntrez ID:79772; OMIM: NA; Uniprot ID:MCTP1_HUMAN; ENSEMBL ID: ENSG00000175471; HGNC ID: 26183
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
bipolar disorder
PSYCH
Desease Name
Bipolar disorder
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of MCTP1 mRNAincreases expression 18687144
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of MCTP1 mRNAdecreases expression 20064835
D007501 Iron Iron deficiency results in increased expression of MCTP1 mRNAincreases expression 20368581
D020849 Raloxifene Raloxifene results in increased expression of MCTP1 mRNAincreases expression 19429434
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0620127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.866695378
MESH:D000419 Albuminuria Raloxifene 5.1017308373 17451421
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 6.2816640825
MESH:D000544 Alzheimer Disease Iron 4.8216640825 16563566
MESH:D000544 Alzheimer Disease Raloxifene 4.8215800139
MESH:D000740 Anemia Iron 4.7616434484 16566752
MESH:D018798 Anemia, Iron-Deficiency Iron 5.0417147795 17162259 17375513 16569441 17163184
MESH:D000756 Anemia, Sideroblastic Iron 5.2416910769
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.6419183758
MESH:D001145 Arrhythmias, Cardiac Iron 4.7616604332
MESH:D001260 Ataxia Telangiectasia Iron 6.0815336622
MESH:D050197 Atherosclerosis Iron 3.9216640825 16632123
MESH:D001321 Autistic Disorder Iron 2.7717352947
MESH:D001424 Bacterial Infections Iron 5.8316640825
MESH:D001930 Brain Injuries Raloxifene 5.0416580743
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.2120146248 17474063
MESH:D001943 Breast Neoplasms Raloxifene 2.2115758505 17049068 16912660 17242785 17893378 17595753 15572757 16837676 15775269 17440819 17261762 17952589
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1320419170
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 4.4717572228
MESH:D009202 Cardiomyopathies Iron 4.2916640825
MESH:D002311 Cardiomyopathy, Dilated Iron 3.5616604332
MESH:D002318 Cardiovascular Diseases Raloxifene 3.7115775269
MESH:D003072 Cognition Disorders Raloxifene 5.1815800139
MESH:D003110 Colonic Neoplasms Iron 2.9416640825
MESH:D003865 Depressive Disorder, Major Raloxifene 4.5317474826
MESH:D003920 Diabetes Mellitus Iron 4.8216640825 16604332
MESH:D003922 Diabetes Mellitus, Type 1 Iron 3.4516506275
MESH:D003924 Diabetes Mellitus, Type 2 Iron 3.1616506275
MESH:D003928 Diabetic Nephropathies Raloxifene 4.3017308373 17451421 15920148
MESH:D004487 Edema Raloxifene 3.7615860553
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 4.5015845917
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0816530937
MESH:D005234 Fatty Liver Iron 9.7716640825
MESH:D005234 Fatty Liver Raloxifene 9.7717473493
MESH:D005621 Friedreich Ataxia Iron 5.9916640825 16604332
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8320471113
MESH:D006331 Heart Diseases Raloxifene 3.8011110106
MESH:D006432 Hemochromatosis Iron 4.7716604332 16640825 17053826 16574947 17236123 17255318
MESH:D006486 Hemosiderosis Iron 5.9416604332
MESH:D006525 Hepatitis, Viral, Human Iron 6.1916640825
MESH:D006527 Hepatolenticular Degeneration Iron 5.5017182432
MESH:D006529 Hepatomegaly Iron 4.8716890145
MESH:D015658 HIV Infections Iron 3.8516597321
MESH:D006973 Hypertension Raloxifene 2.9817577099 15787275
MESH:D007006 Hypogonadism Iron 4.6716640825
MESH:D007037 Hypothyroidism Iron 5.6416640825
MESH:D019189 Iron Metabolism Disorders Iron 5.5017163184
MESH:D007889 Leiomyoma Raloxifene 4.9616973256
MESH:D020961 Lewy Body Disease Iron 5.9916563566
MESH:D008103 Liver Cirrhosis Iron 3.9116640825
MESH:D008108 Liver Diseases, Alcoholic Iron 5.5717207112 16737972
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 5.2621137059 20195826
MESH:D008113 Liver Neoplasms Iron 5.2616640825 20302851
MESH:D055370 Lung Injury Asbestos, Crocidolite 4.5817365036
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.7920464547 6695378 18816296 18520028 18569708 17053015 20869020 20064080 20135361
MESH:D008175 Lung Neoplasms Iron 2.7916640825
MESH:D008268 Macular Degeneration Iron 4.1716640825
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.3116966607 16166281 18303189
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 6.2815863610
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.5016381670
MESH:D009101 Multiple Myeloma Raloxifene 3.7116497877
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 6.3917086897
MESH:D009181 Mycoses Iron 6.1916640825
MESH:D017202 Myocardial Ischemia Iron 4.7716604332
MESH:D015428 Myocardial Reperfusion Injury Iron 4.5716604332
MESH:D009232 Myxoma Raloxifene 6.2816343187
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3311141357
MESH:D009404 Nephrotic Syndrome Iron 4.8817178036
MESH:D019636 Neurodegenerative Diseases Iron 4.5917296847 16604332
MESH:D010003 Osteoarthritis Iron 4.1816640825
MESH:D010024 Osteoporosis Iron 8.3016640825 16648989
MESH:D010024 Osteoporosis Raloxifene 8.3017882678 19059307 15775268
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.6917893378 15579764 17823083 15758505
MESH:D010212 Papilloma Iron 5.0412065085
MESH:D020447 Parasomnias Iron 6.7417352947
MESH:D010300 Parkinson Disease Iron 3.4316563566 16640825
MESH:D010900 Pituitary Diseases Iron 6.3916604332
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 5.4510923243
MESH:D011041 Poisoning Iron 4.7516604332
MESH:D017119 Porphyria Cutanea Tarda Iron 5.4916640825
MESH:D011225 Pre-Eclampsia Iron 4.7316640825
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.2217292933
MESH:D011471 Prostatic Neoplasms Raloxifene 3.2216536755 16220300 15731164
MESH:D011528 Protozoan Infections Iron 6.7416640825
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 3.1517975199 17365031 15814490 17322281
MESH:D011693 Purpura Raloxifene 6.2815770314
MESH:D012148 Restless Legs Syndrome Iron 4.8416930377
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 6.5219755658 10029692
MESH:D012878 Skin Neoplasms Iron 6.5212065085
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.5620155912 2093021
MESH:D020521 Stroke Raloxifene 4.1516837676
MESH:D013398 Sudden Infant Death Iron 6.0816640825
MESH:D013978 Tibial Fractures Raloxifene 5.9319048282
MESH:D014376 Tuberculosis Iron 4.3116597321
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.5917053015
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 5.5917572228
MESH:D054556 Venous Thromboembolism Raloxifene 5.9316837676
MESH:D014846 Vulvar Neoplasms Raloxifene 6.2816343187
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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