Annotation Detail for ZNF408
Basic Information Top
| Gene Symbol: | ZNF408 ( FLJ12827 ) |
|---|---|
| Gene Full Name: | zinc finger protein 408 |
| Band: | 11p11.2 |
| Quick Links | Entrez ID:79797; OMIM: NA; Uniprot ID:ZN408_HUMAN; ENSEMBL ID: ENSG00000175213; HGNC ID: 20041 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D005472 | Fluorouracil | [Fluorouracil co-treated with irinotecan] results in increased expression of ZNF408 mRNA | affects cotreatment|increases expression | 16391804 |
| C051890 | irinotecan | [Fluorouracil co-treated with irinotecan] results in increased expression of ZNF408 mRNA | affects cotreatment|increases expression | 16391804 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000230 | Adenocarcinoma | Fluorouracil | 2.51 | 17638652 | |
| MESH:D000740 | Anemia | Fluorouracil | 4.22 | 15504547 16511603 17963324 | |
| MESH:D001943 | Breast Neoplasms | Fluorouracil | 2.42 | 16110121 15136595 18357371 16595493 16557594 19217205 18608205 | |
| MESH:D002276 | Carcinoid Tumor | Fluorouracil | 5.74 | 16051944 | |
| MESH:D002277 | Carcinoma | Fluorouracil | 3.97 | 17121937 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Fluorouracil | 2.12 | 17045692 18930000 16332177 17088986 16799960 17971768 | |
| MESH:D002292 | Carcinoma, Renal Cell | Fluorouracil | 3.20 | 18695887 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Fluorouracil | 2.59 | 17066447 18986760 16757204 16280240 | |
| MESH:D003110 | Colonic Neoplasms | Fluorouracil | 4.19 | 17287894 17169374 16340194 17018589 17172411 16510598 15001691 17725105 17016597 18772588 | |
| MESH:D003110 | Colonic Neoplasms | irinotecan | 4.19 | 17287894 17725105 | |
| MESH:D015179 | Colorectal Neoplasms | Fluorouracil | 2.81 | 16391804 15289873 18448328 18802399 20501625 17094418 16303861 15148649 18383874 17695437 17016601 16282729 17594712 18288408 16524972 16331619 14970324 18949393 17454858 17401013 17255274 18509181 | |
| MESH:D015179 | Colorectal Neoplasms | irinotecan | 2.81 | 18259882 16303861 18509181 15273666 17454858 16391804 17159606 | |
| MESH:D007644 | Darier Disease | Fluorouracil | 5.68 | 16733453 | |
| MESH:D004938 | Esophageal Neoplasms | Fluorouracil | 2.54 | 17638652 16337965 16785472 16481741 15173087 | |
| MESH:D005910 | Glioma | Fluorouracil | 3.02 | 16145905 | |
| MESH:D006258 | Head and Neck Neoplasms | Fluorouracil | 3.70 | 15162350 18337622 15102660 | |
| MESH:D007680 | Kidney Neoplasms | Fluorouracil | 3.74 | 16985049 | |
| MESH:D008113 | Liver Neoplasms | Fluorouracil | 2.62 | 17045692 15113037 18383874 16603448 | |
| MESH:D008175 | Lung Neoplasms | Fluorouracil | 2.01 | 15246190 | |
| MESH:D008178 | Lupus Erythematosus, Cutaneous | Fluorouracil | 5.68 | 15086387 | |
| MESH:D009062 | Mouth Neoplasms | Fluorouracil | 4.02 | 16757204 18986760 | |
| MESH:D052016 | Mucositis | irinotecan | 5.89 | 17159606 | |
| MESH:D009362 | Neoplasm Metastasis | irinotecan | 3.32 | 18259882 | |
| MESH:D009369 | Neoplasms | Fluorouracil | 2.80 | 18600527 16928823 18239605 | |
| MESH:D009447 | Neuroblastoma | irinotecan | 3.69 | 8761367 | |
| MESH:D017599 | Neuroectodermal Tumors | irinotecan | 5.62 | 8761367 | |
| MESH:D020258 | Neurotoxicity Syndromes | Fluorouracil | 3.75 | 16436463 | |
| MESH:D010190 | Pancreatic Neoplasms | Fluorouracil | 2.79 | 15113037 19003803 16500647 16929163 | |
| MESH:D011471 | Prostatic Neoplasms | Fluorouracil | 3.34 | 18626508 19082440 | |
| MESH:D012004 | Rectal Neoplasms | Fluorouracil | 4.48 | 18286688 15538739 18722050 16160472 | |
| MESH:D013274 | Stomach Neoplasms | Fluorouracil | 2.80 | 19015929 16951190 18567086 15786421 17172411 16424979 19084572 17498489 18396642 17522103 | |
| MESH:D013274 | Stomach Neoplasms | irinotecan | 2.80 | 15723263 | |
| MESH:D014062 | Tongue Neoplasms | Fluorouracil | 4.50 | 16280240 | |
| MESH:D002583 | Uterine Cervical Neoplasms | Fluorouracil | 4.38 | 16803524 |
| No data |