AutismKB 2.0

Annotation Detail for HHIPL2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:HHIPL2 ( FLJ13840,KIAA1822L )
Gene Full Name: HHIP-like 2
Band: 1q41
Quick LinksEntrez ID:79802; OMIM: NA; Uniprot ID:HIPL2_HUMAN; ENSEMBL ID: ENSG00000143512; HGNC ID: 25842
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of HHIPL2 mRNAaffects cotreatment|decreases expression 19619570
D004958 Estradiol Estradiol results in increased expression of HHIPL2 mRNAincreases expression 19619570
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of HHIPL2 mRNAaffects cotreatment|decreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of HHIPL2 mRNAdecreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of HHIPL2 mRNAincreases expression 15328365
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.7315322242 11752688 14514962
MESH:D000230 Adenocarcinoma Estradiol 2.1811473722
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 4.2616835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.4511748828
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.5912125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.8615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 3.0515746008
MESH:D001943 Breast Neoplasms Estradiol 1.9017289903 17018787 12948864 19861407 17261762 16675129 14630087 18497071
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9020435547
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 5.3516111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 3.2116835633
MESH:D006528 Carcinoma, Hepatocellular Estradiol 1.8016924424
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.6018670907 16120746 18850075
MESH:D002471 Cell Transformation, Neoplastic Estradiol 3.0918566989
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.6316835633
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.2615668235 15340226 12621046 16354765 8697196
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.5317141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2715322242 10048152 20055451
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7517107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.8819279558
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 1.6320420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 3.1211462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.9211000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.9716714409 15322242 18230668
MESH:D016889 Endometrial Neoplasms Estradiol 3.2811473722 19148513 18566989
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.539294722 10568697
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.3811564622
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 4.2211858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.7120067830
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.6610696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.5511294989 10048152
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.8911000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.6515340226 16120746 12621046
MESH:D006558 Herpes Genitalis Estradiol 6.1015709030
MESH:D019584 Hot Flashes Estradiol 4.8217088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 5.1215340226 18606429 8697196 16959395 16354765
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 2.0418850075 18670907
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 2.0612200463 12878042
MESH:D007333 Insulin Resistance Estradiol 3.2616627594 16393666
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.8916580747
MESH:D007674 Kidney Diseases Estradiol 2.8315618244
MESH:D007680 Kidney Neoplasms Estradiol 3.4115610895
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 2.3714659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.3712878042
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 1.8516984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.3812151625
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 1.2411884234 19555203
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.8511807958 11408345 16891317 17203775
MESH:D020149 Manganese Poisoning Estradiol 5.5519453300
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.4312213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.6616810080
MESH:D009389 Neovascularization, Pathologic Estradiol 4.6217289903
MESH:D009421 Nervous System Malformations Estradiol 11.8116427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 11.8114600291
MESH:D010051 Ovarian Neoplasms Estradiol 2.3319401270
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 5.3212520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 4.2318163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 4.0811222880 11399792 11118676 11896295
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.4420887781
MESH:D011471 Prostatic Neoplasms Estradiol 3.0116740699
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.5118990726
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.2316192470
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.9712697716
MESH:D013978 Tibial Fractures Estradiol 5.7619048282
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.6612125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 5.3215886252
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved