AutismKB 2.0

Annotation Detail for GSTCD


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Basic Information Top
Gene Symbol:GSTCD ( DKFZp686I10174,FLJ13273 )
Gene Full Name: glutathione S-transferase, C-terminal domain containing
Band: 4q24
Quick LinksEntrez ID:79807; OMIM: NA; Uniprot ID:GSTCD_HUMAN; ENSEMBL ID: ENSG00000138780; HGNC ID: 25806
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
CARDIOVASCULAR
pulmonary function
Desease Name
Pulmonary function
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of GSTCD mRNAincreases expression 20127859
D016572 Cyclosporine Cyclosporine results in decreased expression of GSTCD mRNAdecreases expression 20106945
D003561 Cytarabine Cytarabine results in increased expression of GSTCD mRNAincreases expression 19194470
C031280 pyrazole pyrazole results in increased expression of GSTCD mRNAincreases expression 17945193
D012402 Rotenone Rotenone results in increased expression of GSTCD mRNAincreases expression 19013527
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0520464547 20127859
MESH:D000236 Adenoma Benzo(a)pyrene 2.846695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.5619183758
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0020146248 17474063
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1320419170
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.9112371664
MESH:D002471 Cell Transformation, Neoplastic Cytarabine 7.918243401
MESH:D002779 Cholestasis Cyclosporine 3.1719486331
MESH:D056486 Drug-Induced Liver Injury pyrazole 3.0912499123
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0716530937
MESH:D005234 Fatty Liver Cyclosporine 3.2319224547
MESH:D005355 Fibrosis Cyclosporine 3.6212639820 12168785
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.768708960
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8220471113
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.9615720958
MESH:D006689 Hodgkin Disease Cytarabine 4.7416200630
MESH:D006973 Hypertension Cyclosporine 2.2010903974
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.0515604871
MESH:D007674 Kidney Diseases Cyclosporine 2.5218776723 10903974 8314463
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0412371664
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 2.1421137059 20195826
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5720869020 20464547 20135361 18569708 18520028 18816296 6695378 20064080 17053015
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.4016801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4616381670
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3111141357
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.0517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6119348381 18481113
MESH:D009410 Nerve Degeneration Rotenone 4.1515790535 18619942 17356569
MESH:D010300 Parkinson Disease Rotenone 3.0816412576 11535288 19232380 19114014 16140633 15451049 18619942 11445065 18191903
MESH:D020734 Parkinsonian Disorders Rotenone 4.4215795934 18197244 15574749 15927086
MESH:D011230 Precancerous Conditions Cyclosporine 3.5512371664
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cytarabine 4.6121297632
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9117292933
MESH:D011565 Psoriasis Cyclosporine 2.3216882103
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5119755658 10029692
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D013733 Testicular Diseases pyrazole 5.366499806
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.2917053015
MESH:D014605 Uveitis Cyclosporine 4.591336536
MESH:D014985 Xerophthalmia Cyclosporine 5.0517120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA144596427
  • No data
    Releated disease ID Related disease Name
    PA443450Asthma
    PA447178Pulmonary Disease, Chronic Obstructive
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018