Annotation Detail for METTL8
Basic Information Top
| Gene Symbol: | METTL8 ( FLJ13334,FLJ13984,FLJ31054,FLJ42098,FLJ77788,TIP ) |
|---|---|
| Gene Full Name: | methyltransferase like 8 |
| Band: | 2q31.1 |
| Quick Links | Entrez ID:79828; OMIM: 609525; Uniprot ID:A8K7U3_HUMAN; ENSEMBL ID: ENSG00000123600; HGNC ID: 25856 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of METTL8 mRNA | affects expression | 17562736 |
| D004041 | Dietary Fats | Dietary Fats results in decreased expression of METTL8 mRNA | decreases expression | 18042831 |
| C041786 | palm oil | palm oil results in decreased expression of METTL8 mRNA | decreases expression | 18042831 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 4.71 | 10982225 | |
| MESH:D001161 | Arteriosclerosis | Dietary Fats | 4.54 | 15238619 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D001943 | Breast Neoplasms | Dietary Fats | 2.24 | 20435547 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.81 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 10774834 19370779 16109766 11743745 19416960 10663392 11421492 16485898 15968718 12392966 16781746 11529661 10915739 12594235 16081117 18713872 14725611 19164858 17522070 16393943 16177239 12153990 19420014 11739529 19085960 12540782 17906064 2444490 11287661 12705907 12958197 17562736 18071297 19923254 19739265 14550746 15619225 11461765 14986274 11834606 16227642 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.96 | 19426721 | |
| MESH:D050171 | Dyslipidemias | Dietary Fats | 3.76 | 18367378 | |
| MESH:D005234 | Fatty Liver | Dietary Fats | 3.72 | 18296743 19004024 17967931 19551842 | |
| MESH:D005355 | Fibrosis | Dietary Fats | 4.17 | 18296743 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.54 | 16983495 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.06 | 16870215 | |
| MESH:D006937 | Hypercholesterolemia | Dietary Fats | 4.08 | 21332399 | |
| MESH:D006949 | Hyperlipidemias | Dietary Fats | 4.14 | 21332399 | |
| MESH:D007249 | Inflammation | Dietary Fats | 2.62 | 20412841 | |
| MESH:D007333 | Insulin Resistance | Dietary Fats | 3.37 | 11836018 18457598 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.42 | 12587719 15629191 | |
| MESH:D008103 | Liver Cirrhosis | Dietary Fats | 3.09 | 18296743 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 12969438 19460945 19014921 16611625 19784758 12587719 11587558 16610002 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.68 | 17185352 16871587 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.22 | 19513568 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.26 | 18514411 | |
| MESH:D009765 | Obesity | Dietary Fats | 2.36 | 18457598 17217161 11836018 21332399 18674790 20518802 20132043 16723640 19632207 | |
| MESH:D010146 | Pain | Acetaminophen | 2.77 | 16870215 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.50 | 10982225 | |
| MESH:D015430 | Weight Gain | Dietary Fats | 4.15 | 16723640 |
| No data |