AutismKB 2.0

Annotation Detail for ALG13


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Basic Information Top
Gene Symbol:ALG13 ( CXorf45,FLJ23018,FLJ31785,GLT28D1,MDS031,MGC12423,YGL047W )
Gene Full Name: asparagine-linked glycosylation 13 homolog (S. cerevisiae)
Band: Xq23
Quick LinksEntrez ID:79868; OMIM: 300776; Uniprot ID:ALG13_HUMAN; ENSEMBL ID: ENSG00000101901; HGNC ID: 30881
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESISdolichyl-diphosphooligosaccharide biosynthesis
Pathway IDPathway Name
hsa00510N-Glycan biosynthesis
hsa01100Metabolic pathways
Pathway IDPathway Name
Metabolism of proteins
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No data
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C006632 arsenic trioxide arsenic trioxide results in increased expression of ALG13 mRNAincreases expression 15761015
D002117 Calcitriol Calcitriol results in decreased expression of ALG13 mRNAdecreases expression 16002434
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma arsenic trioxide 2.3711798837 19825857
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 4.2216206674
MESH:D001943 Breast Neoplasms Calcitriol 2.5611237771
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.9411589617
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 1.9914691202 16217749 15073043 11135700 15553829
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.9419014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.6312490120
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 2.7211237771
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8720501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.8612609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.9010525206
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.7015213294
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 4.6115138306
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.4012903497
MESH:D005234 Fatty Liver arsenic trioxide 3.8415073043
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.9416904648
MESH:D007938 Leukemia arsenic trioxide 3.0315070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.3512560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 5.1916972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.7914633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.3119077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1917050201 16467208 20471514 16968895 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.5117107899 17869043 15336539 17217047 19035177 19225113 11468182 12018890 9834237 16966277 19642359 12679006 12712474 11161223 15748426 17649720 16330433 19075265 16331271 15622746 16112521 16891316 17712046 15213294 16823087
MESH:D015458 Leukemia, T-Cell arsenic trioxide 5.0316882451
MESH:D008113 Liver Neoplasms arsenic trioxide 2.4814682389
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 3.0120377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.7315213294
MESH:D008175 Lung Neoplasms arsenic trioxide 1.8719825857 11798837
MESH:D009101 Multiple Myeloma arsenic trioxide 3.4411468182 19417148 15949261 14977855 19549372
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.7418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3816105982 16882451
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.6316624393
MESH:D009436 Neural Tube Defects arsenic trioxide 3.4110525206
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.5212452020 19769630 16624393
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6615580305
MESH:D010235 Paraganglioma arsenic trioxide 4.7719927285
MESH:D011470 Prostatic Hyperplasia Calcitriol 5.6715572423
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.2919131511
MESH:D011471 Prostatic Neoplasms Calcitriol 3.2915754350 16644109 18247401 12479363 16289102
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.6316646077
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.4719014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.8515213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 2.6220435036 11780464 12845720 12973940
Pathway ID Pathway Name
KEGG:01100 Metabolic pathways
REACT:17015 Metabolism of proteins
KEGG:00510 N-Glycan biosynthesis
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018