AutismKB 2.0

Annotation Detail for CBLL1


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Basic Information Top
Gene Symbol:CBLL1 ( FLJ23109,HAKAI,MGC163401,MGC163403,RNF188 )
Gene Full Name: Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
Band: 7q22.3
Quick LinksEntrez ID:79872; OMIM: 606872; Uniprot ID:HAKAI_HUMAN; ENSEMBL ID: ENSG00000105879; HGNC ID: 21225
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of CBLL1 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of CBLL1 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of CBLL1 mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of CBLL1 proteinaffects expression 20106945
D016572 Cyclosporine Cyclosporine results in increased expression of CBLL1 mRNAincreases expression 20106945
D004041 Dietary Fats Dietary Fats results in decreased expression of CBLL1 mRNAdecreases expression 18042831
C041786 palm oil palm oil results in decreased expression of CBLL1 mRNAdecreases expression 18042831
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.2910982225
MESH:D001161 Arteriosclerosis Dietary Fats 4.2515238619
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms Dietary Fats 2.2520435547
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 6.8516705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 6.8516705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 6.853084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 6.8521507988 12907637 12619106
MESH:D002386 Cataract Acetaminophen 2.7310977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 7.196135515
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.1912371664
MESH:D002779 Cholestasis Cyclosporine 3.1219486331
MESH:D003490 Cyanosis 2,4-dinitrotoluene 12.1218551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 12.1218551238
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 6.5821346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 6.5818551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.5817562736 10915739 16393943 17906064 17522070 19739265 18071297 11287661 11834606 12153990 19416960 14725611 12392966 10663392 19085960 16781746 16109766 12594235 14986274 19164858 19370779 14550746 16177239 11529661 16227642 19420014 12958197 16485898 12705907 12540782 11421492 18713872 11461765 11743745 15968718 11739529 10774834 19923254 16081117 2444490 15619225
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.5419426721
MESH:D050171 Dyslipidemias Dietary Fats 3.6518367378
MESH:D005234 Fatty Liver Cyclosporine 8.6919224547
MESH:D005234 Fatty Liver Dietary Fats 8.6917967931 18296743 19551842 19004024
MESH:D005355 Fibrosis Cyclosporine 9.9212168785 12639820
MESH:D005355 Fibrosis Dietary Fats 9.9218296743
MESH:D005756 Gastritis Acetaminophen 4.1216983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.628708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.8215720958
MESH:D006930 Hyperalgesia Acetaminophen 2.9216870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.8721332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.9221332399
MESH:D006973 Hypertension Cyclosporine 2.1810903974
MESH:D007249 Inflammation Dietary Fats 2.5520412841
MESH:D007333 Insulin Resistance Dietary Fats 3.2711836018 18457598
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.8815604871
MESH:D007674 Kidney Diseases Acetaminophen 6.2815629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 6.2818776723 10903974 8314463
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 13.7616705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 13.7616705839
MESH:D007680 Kidney Neoplasms Cyclosporine 13.7612371664
MESH:D008103 Liver Cirrhosis Dietary Fats 3.0118296743
MESH:D008107 Liver Diseases Acetaminophen 1.6819460945 16610002 12969438 16611625 19014921 11587558 19784758 12587719
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5016871587 17185352
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 4.907678174
MESH:D008113 Liver Neoplasms Aflatoxin B1 4.909163691 18177683 15890375 2125692
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 6.512876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 6.518603461
MESH:D008175 Lung Neoplasms Aflatoxin B1 1.8714755239
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9319513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.2316801185
MESH:D009336 Necrosis 2,4-dinitrotoluene 11.7018551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 11.7018551238 7678174
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.8817954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5318481113 19348381
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1018514411
MESH:D009765 Obesity Dietary Fats 2.3421332399 20518802 19632207 17217161 18674790 16723640 11836018 20132043 18457598
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 9.7816049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 9.7816049721
MESH:D010146 Pain Acetaminophen 2.6216870215
MESH:D011230 Precancerous Conditions Cyclosporine 3.4712371664
MESH:D011565 Psoriasis Cyclosporine 2.3016882103
MESH:D012640 Seizures 2,4-dinitrotoluene 6.4718551238
MESH:D012640 Seizures 2,6-dinitrotoluene 6.4718551238
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 5.3216049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.3216049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 13.3510091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 13.3510091137
MESH:D014581 Urticaria Acetaminophen 3.2810982225
MESH:D014605 Uveitis Cyclosporine 4.431336536
MESH:D015430 Weight Gain Dietary Fats 3.9916723640
MESH:D014985 Xerophthalmia Cyclosporine 4.8817120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA134960329
    • Releated gene ID Related gene Name
    PA134960329CBLL1
    No data
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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