AutismKB 2.0

Annotation Detail for ZC3H14


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Basic Information Top
Gene Symbol:ZC3H14 ( FLJ11806,MGC26892,NY-REN-37,SUT2,UKp68 )
Gene Full Name: zinc finger CCCH-type containing 14
Band: 14q31.3
Quick LinksEntrez ID:79882; OMIM: 613279; Uniprot ID:ZC3HE_HUMAN; ENSEMBL ID: ENSG00000100722; HGNC ID: 20509
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of ZC3H14 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of ZC3H14 mRNAaffects expression 21346803
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of ZC3H14 mRNAaffects expression 17555576
D013629 Tamoxifen Tamoxifen affects the expression of ZC3H14 mRNAaffects expression 17555576
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 5.2714745880
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.6617505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8814692618
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.0211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8915885639
MESH:D001943 Breast Neoplasms Tamoxifen 2.1721138602 19142967 19103187 19155303 19011961 16202921 16273361 19289846 15668708 11161223 19410462 18629630 19084267 20065188 18815881 18997820 21152245 18984771 19244106 16818667 17261762 18821012 19200415 18855134 19059307 18425577 17242785 19066611 17440819 18351453 20859285 20005174 15565566 19221464 20544844 19189210 17049068 16873071 19487384 20135344 19115204 17893378 20390343 19288272 19189212
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 5.0719066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 4.8416705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 4.8416705839
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 4.8416924424
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 4.0117572228
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.036135515
MESH:D002779 Cholestasis Ethinyl Estradiol 3.1711677210 17110522 17681005 16105132 16919318 17333356 15861022
MESH:D003490 Cyanosis 2,4-dinitrotoluene 12.8318551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 12.8318551238
MESH:D003711 Demyelinating Diseases Tamoxifen 4.9219031437
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.8419279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 4.1621346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 4.1618551238 21346803
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 10.6812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 10.6819031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.2919155303 20544844 16202921 17893378
MESH:D005234 Fatty Liver Ethinyl Estradiol 9.1415345470
MESH:D005234 Fatty Liver Tamoxifen 9.1419224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.4516709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 5.1614745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.8119069698
MESH:D007021 Hypospadias Ethinyl Estradiol 4.3716945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7317937319
MESH:D007249 Inflammation Tamoxifen 2.5319457130
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 14.4816705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 14.4816705839
MESH:D007680 Kidney Neoplasms Tamoxifen 14.4818625569
MESH:D008064 Lipidoses Tamoxifen 3.4317567588 15342952
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 1.7518564211
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 4.967678174
MESH:D008113 Liver Neoplasms Tamoxifen 4.9616684651
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.772876786 2876784 6135515
MESH:D008175 Lung Neoplasms Tamoxifen 1.7418625569
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.3919428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.8616827153 11731420 19196722 14580682 19196723
MESH:D020149 Manganese Poisoning Tamoxifen 5.2719453300
MESH:D008545 Melanoma Tamoxifen 1.9219393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.8115990972
MESH:D009336 Necrosis 2,4-dinitrotoluene 12.5418551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 12.5418551238 7678174
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.6719393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.6119410462
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.7219189210 19200415 19196722
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 10.2316049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 10.2316049721
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.1511578682
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.0915067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.9416919318 15861022
MESH:D012640 Seizures 2,4-dinitrotoluene 6.7418551238
MESH:D012640 Seizures 2,6-dinitrotoluene 6.7418551238
MESH:D013088 Spermatocele Ethinyl Estradiol 14.1116709447
MESH:D013088 Spermatocele Tamoxifen 14.1116709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.6719457130
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.0811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5215669648
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 9.0416049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 9.0416049721
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 9.048653321 17572228 16712894
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 14.1910091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 14.1910091137
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8014692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.9715869587 14671159
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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