AutismKB 2.0

Annotation Detail for RIN3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RIN3 ( DKFZp762H1613,FLJ11700,FLJ22439 )
Gene Full Name: Ras and Rab interactor 3
Band: 14q32.13
Quick LinksEntrez ID:79890; OMIM: 610223; Uniprot ID:RIN3_HUMAN; ENSEMBL ID: ENSG00000100599; HGNC ID: 18751
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
CHEMDEPENDENCY
smoking cessation
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of RIN3 mRNAaffects expression 17562736
D000638 Amiodarone Amiodarone results in increased expression of RIN3 mRNAincreases expression 19774075
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of RIN3 mRNAaffects cotreatment|increases expression 17183730
C016599 mono-(2-ethylhexyl)phthalate mono-(2-ethylhexyl)phthalate results in increased expression of RIN3 mRNAincreases expression 16809437
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of RIN3 mRNAaffects cotreatment|increases expression 17183730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 4.028875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.3019490988
MESH:D000550 Amblyopia Valproic Acid 5.8517688650
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D001008 Anxiety Disorders Valproic Acid 3.8617497229
MESH:D001145 Arrhythmias, Cardiac Amiodarone 4.1518057881 18218290 20041841
MESH:D001281 Atrial Fibrillation Amiodarone 4.1618651412 19698954
MESH:D001321 Autistic Disorder Acetaminophen 1.8618445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8618177632 17688650 17507914 18940202 18985861 17157402 16609825 19232924 18558336 19460635 18316065 18396377 20603192 18775368 15238991
MESH:D001714 Bipolar Disorder Valproic Acid 3.2320046352 17594078
MESH:D001778 Blood Coagulation Disorders Amiodarone 4.2719483382
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.618888407
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.403084413
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.9915710769 19225199
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.6218974383
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.8120734317
MESH:D019465 Craniofacial Abnormalities Valproic Acid 1.9017688650 16575769 8888407
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.7616177239 17906064 2444490 11529661 19923254 14550746 11834606 11421492 16109766 16781746 19164858 12705907 11739529 12153990 19420014 19739265 17562736 10663392 11743745 11287661 12594235 17522070 14986274 19416960 15619225 18071297 10774834 11461765 19370779 15968718 16081117 14725611 16393943 12540782 19085960 12958197 16485898 10915739 18713872 12392966 16227642
MESH:D056486 Drug-Induced Liver Injury Amiodarone 6.7618218290 15265979
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 6.761733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D004421 Dystonia Valproic Acid 4.451851702
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.6417275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 4.5316628512 3922381
MESH:D004827 Epilepsy Valproic Acid 3.0920417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.916426943 6254150 7562514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.787750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.603659116
MESH:D005234 Fatty Liver Amiodarone 9.2714986274
MESH:D005234 Fatty Liver Valproic Acid 9.2719224547 14986274
MESH:D005315 Fetal Diseases Valproic Acid 5.5016575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.578888407 18558336
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D006529 Hepatomegaly Amiodarone 4.2315265979
MESH:D006849 Hydrocephalus Valproic Acid 5.4117688650
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D006937 Hypercholesterolemia Amiodarone 4.259751232 8137927
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 5.1116612254
MESH:D007037 Hypothyroidism Amiodarone 5.0017991464 18020914
MESH:D007674 Kidney Diseases Acetaminophen 2.3812587719 15629191
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1916294345 17596541
MESH:D008064 Lipidoses Amiodarone 3.7617567588 15342952
MESH:D008107 Liver Diseases Acetaminophen 1.6912969438 19784758 16611625 19460945 11587558 12587719 16610002 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5817185352 16871587
MESH:D008133 Long QT Syndrome Amiodarone 3.8515350150 17391786 11989578
MESH:D008171 Lung Diseases Amiodarone 3.6012587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 13.3918516814
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 13.3917228818
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D008881 Migraine Disorders Valproic Acid 3.4418765137 18803445
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.408888407
MESH:D009181 Mycoses Amiodarone 5.5112754197 17974566
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3317596541
MESH:D009436 Neural Tube Defects Valproic Acid 3.348888407 16359493
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 4.3720603192
MESH:D019310 Pseudolymphoma Valproic Acid 5.1512752131 11422049
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.9611597910 12832656 12490602
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.5819155313
MESH:D012559 Schizophrenia Valproic Acid 2.1019110320 15737665
MESH:D012640 Seizures Valproic Acid 2.9614763951 17978042 16876388 3137016 11044598 11738929 15475178 1511512
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.6218724381
MESH:D016135 Spinal Dysraphism Valproic Acid 4.0619490988
MESH:D013226 Status Epilepticus Valproic Acid 5.1512833885
MESH:D013276 Stomach Ulcer Amiodarone 3.6818087811
MESH:D013610 Tachycardia Amiodarone 4.7311238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.6319225199
MESH:D013959 Thyroid Diseases Amiodarone 5.3719731979
MESH:D013971 Thyrotoxicosis Amiodarone 5.3418020914 19584973
MESH:D016171 Torsades de Pointes Amiodarone 4.7311989578 17467628
MESH:D014178 Translocation, Genetic Valproic Acid 5.8517262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 5.063119515
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.138888407
MESH:D014581 Urticaria Acetaminophen 3.3810982225
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved