Annotation Detail for NUP85

Basic Information
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| Pathway ID | Pathway Name |
|---|
| Metabolism of carbohydrates |
| Cell Cycle, Mitotic |
| DNA Replication |
| Transmembrane transport of small molecules |
| HIV Infection |
| Pathway ID | Pathway Name |
|---|
| 500347 | Regulation of Glucokinase by Glucokinase Regulatory Protein |
| 500899 | Transport of the SLBP Dependant Mature mRNA |
| 500748 | Vpr-mediated nuclear import of PICs |
| 500734 | Late Phase of HIV Life Cycle |
| 500858 | snRNP Assembly |
| 500687 | Transport of Ribonucleoproteins into the Host Nucleus |
| 500696 | NEP/NS2 Interacts with the Cellular Export Machinery |
| 500928 | Transport of Mature mRNA derived from an Intron-Containing Transcript |
| 500749 | Interactions of Rev with host cellular proteins |
| 500744 | Rev-mediated nuclear export of HIV-1 RNA |
| 500657 | Transport of Mature Transcript to Cytoplasm |
| 500862 | Transport of Mature mRNA Derived from an Intronless Transcript |
| 500879 | Transport of the SLBP independent Mature mRNA |
| 500658 | Transport of Mature mRNAs Derived from Intronless Transcripts |
| 500750 | Nuclear import of Rev protein |
| Desease ID | Desease Name |
|---|
| 2075 | Heart failure |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of NUP85 mRNA | affects expression | 17562736
|
| D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of NUP85 mRNA | decreases expression | 20382639 19150397
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.91 | 10982225 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.39 | 18445737 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
1.41 | 3084413 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.83 | 10977129 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
3.04 | 20889678 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
1.68 | 11421492 14986274 17522070 14550746 19416960 16109766 16081117 11529661 19739265 16227642 12705907 11743745 11287661 11739529 11461765 2444490 15968718 12392966 14725611 19085960 16781746 18713872 10915739 12958197 18071297 19420014 17906064 11834606 19923254 12594235 17562736 12153990 16485898 19164858 19370779 10774834 15619225 16177239 12540782 10663392 16393943 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
5.17 | 19426721 |
| MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.16 | 20426865 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.74 | 16983495 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
3.11 | 16870215 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.44 | 12587719 15629191 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.71 | 19784758 16611625 19460945 12969438 12587719 16610002 11587558 19014921 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.74 | 16871587 17185352 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.33 | 19513568 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.31 | 18514411 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.82 | 16870215 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.58 | 10982225 |