AutismKB 2.0

Annotation Detail for MAGIX


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Basic Information Top
Gene Symbol:MAGIX ( FLJ21687,JM10,MGC138889,PDZX )
Gene Full Name: MAGI family member, X-linked
Band: Xp11.23
Quick LinksEntrez ID:79917; OMIM: NA; Uniprot ID:MAGIX_HUMAN; ENSEMBL ID: ENSG00000017621; HGNC ID: 30006
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of MAGIX mRNAaffects expression 17562736
D004041 Dietary Fats Dietary Fats results in increased expression of MAGIX mRNAincreases expression 18042831
D010126 Ozone Ozone results in decreased expression of MAGIX mRNAdecreases expression 17460151
C041786 palm oil palm oil results in increased expression of MAGIX mRNAincreases expression 18042831
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of MAGIX mRNA]affects reaction|decreases expression 19482888
D010634 Phenobarbital Phenobarbital results in decreased expression of MAGIX mRNAdecreases expression 19482888
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 3.986195326
MESH:D018248 Adenoma, Liver Cell Phenobarbital 4.5117620307
MESH:D000544 Alzheimer Disease Ozone 2.5015513908
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D001161 Arteriosclerosis Dietary Fats 4.3715238619
MESH:D001172 Arthritis, Rheumatoid Ozone 2.6215570426
MESH:D001249 Asthma Ozone 2.7217854713 16373670
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms Dietary Fats 2.2520435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.9616777450 19059883 17626835 18315731 14754758 18417511 15516495
MESH:D002100 Cachexia Ozone 5.2816183385
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 3.013084413
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 3.0120007298 17173139 6705139 1701930 20935162
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.744080065
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6611529661 19739265 18071297 11287661 11739529 16081117 19164858 19416960 16393943 11461765 19923254 10915739 10774834 16109766 11743745 12958197 18713872 16781746 2444490 16227642 12153990 14725611 17562736 14986274 16485898 11834606 15619225 17522070 14550746 16177239 19370779 11421492 10663392 19085960 12540782 15968718 12392966 12705907 19420014 17906064 12594235
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D050171 Dyslipidemias Dietary Fats 3.7018367378
MESH:D004421 Dystonia Phenobarbital 4.411851702
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.593659116
MESH:D004828 Epilepsies, Partial Phenobarbital 4.483922381 11558140
MESH:D004827 Epilepsy Phenobarbital 3.0420417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.876401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.747750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.563659116
MESH:D005234 Fatty Liver Dietary Fats 3.6119004024 17967931 19551842 18296743
MESH:D005355 Fibrosis Dietary Fats 4.0118296743
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D006529 Hepatomegaly Phenobarbital 3.9716109766
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.9721332399
MESH:D006949 Hyperlipidemias Dietary Fats 4.0221332399
MESH:D007249 Inflammation Dietary Fats 2.5920412841
MESH:D007333 Insulin Resistance Dietary Fats 3.3211836018 18457598
MESH:D007674 Kidney Diseases Acetaminophen 2.3812587719 15629191
MESH:D008103 Liver Cirrhosis Dietary Fats 7.2418296743
MESH:D008103 Liver Cirrhosis Phenobarbital 7.2421047994
MESH:D008107 Liver Diseases Acetaminophen 4.1711587558 19460945 12587719 16611625 16610002 12969438 19784758 19014921
MESH:D008107 Liver Diseases Phenobarbital 4.1719363144
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5816871587 17185352
MESH:D008113 Liver Neoplasms Phenobarbital 2.4119812893 21047994 8742319 19482888 15975961 19073162
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 2.9018308698 17172636 6150874 1399818 2563599
MESH:D008171 Lung Diseases Ozone 3.608266340 19066396
MESH:D055370 Lung Injury Ozone 4.3320417186
MESH:D008175 Lung Neoplasms Ozone 2.107614698 8597069
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D008679 Metaplasia Ozone 5.7210496685
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 5.0217484760
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D009765 Obesity Dietary Fats 2.3516723640 17217161 20518802 20132043 18457598 11836018 18674790 21332399 19632207
MESH:D010018 Osteomalacia Phenobarbital 4.9017016548
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.5916965848
MESH:D010538 Peritonitis Ozone 4.6116369182
MESH:D011014 Pneumonia Ozone 4.9318007984 18929643 18381685
MESH:D011230 Precancerous Conditions Phenobarbital 3.952563599
MESH:D019310 Pseudolymphoma Phenobarbital 5.1112752131
MESH:D012640 Seizures Phenobarbital 2.924039156 3137016 11442880 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 5.366407741
MESH:D013964 Thyroid Neoplasms Phenobarbital 3.321399818
MESH:D014581 Urticaria Acetaminophen 3.3810982225
MESH:D015430 Weight Gain Dietary Fats 4.0616723640
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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