AutismKB 2.0

Annotation Detail for ADM2


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Basic Information Top
Gene Symbol:ADM2 ( AM2,FLJ21135,dJ579N16.4 )
Gene Full Name: adrenomedullin 2
Band: 22q13.33
Quick LinksEntrez ID:79924; OMIM: 608682; Uniprot ID:ADM2_HUMAN; ENSEMBL ID: ENSG00000128165; HGNC ID: 28898
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
Signaling by GPCR
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of ADM2 mRNAincreases expression 16002435
D004958 Estradiol Estradiol results in increased expression of ADM2 mRNAincreases expression 16002435
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Estradiol 2.1811473722
MESH:D000686 Amyloidosis Diethylstilbestrol 5.1615469931
MESH:D001943 Breast Neoplasms Diethylstilbestrol 2.2317129689 15324884
MESH:D001943 Breast Neoplasms Estradiol 2.2316675129 18497071 12948864 14630087 19861407 17018787 17261762 17289903
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 5.3516111702
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 3.3115948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Estradiol 3.3116924424
MESH:D002471 Cell Transformation, Neoplastic Estradiol 3.0918566989
MESH:D003456 Cryptorchidism Diethylstilbestrol 5.2316002989 12952375
MESH:D003928 Diabetic Nephropathies Estradiol 3.8819279558
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 5.5816402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 8.5415700306 16804899
MESH:D016889 Endometrial Neoplasms Estradiol 8.5419148513 18566989 11473722
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.9216534752 16002989 16611131 16513791 15751030
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 5.8316452187
MESH:D006558 Herpes Genitalis Estradiol 6.1015709030
MESH:D019584 Hot Flashes Estradiol 4.8217088409
MESH:D006965 Hyperplasia Diethylstilbestrol 5.2014722030 12960047
MESH:D007021 Hypospadias Diethylstilbestrol 5.3416002989
MESH:D007246 Infertility Diethylstilbestrol 5.0315036965
MESH:D007333 Insulin Resistance Estradiol 3.2616393666 16627594
MESH:D007674 Kidney Diseases Estradiol 2.8315618244
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 9.0216762066 14681315 15003126
MESH:D007680 Kidney Neoplasms Estradiol 9.0215610895
MESH:D007859 Learning Disorders Diethylstilbestrol 4.8217184923
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 1.6914659978 14716833
MESH:D008113 Liver Neoplasms Diethylstilbestrol 2.7716712894 15890375
MESH:D008181 Lupus Nephritis Diethylstilbestrol 6.0415166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.8115700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 6.5916002989
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.8517203775 11807958 16891317 11408345
MESH:D020149 Manganese Poisoning Estradiol 5.5519453300
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.6616810080
MESH:D009369 Neoplasms Diethylstilbestrol 2.9615313581
MESH:D009389 Neovascularization, Pathologic Estradiol 4.6217289903
MESH:D009421 Nervous System Malformations Diethylstilbestrol 12.1511399458
MESH:D009421 Nervous System Malformations Estradiol 12.1516427766 11399458
MESH:D010051 Ovarian Neoplasms Estradiol 2.3319401270
MESH:D010900 Pituitary Diseases Diethylstilbestrol 6.2414722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 5.4316977796 15687265
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 5.0017184923
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.4420887781
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 3.2317136230 15046698 15846301
MESH:D011471 Prostatic Neoplasms Estradiol 3.2316740699
MESH:D013088 Spermatocele Diethylstilbestrol 5.7816709447 16002989
MESH:D013978 Tibial Fractures Estradiol 5.7619048282
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 2.9216452187 16712894 17306315
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 4.5416175088
MESH:D014591 Uterine Diseases Diethylstilbestrol 6.2414652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 4.7415809267 16690809
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 5.2016513791 16002989
Pathway ID Pathway Name
REACT:14797 Signaling by GPCR
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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