Annotation Detail for ADCK4
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of ADCK4 mRNA | affects expression | 21346803
|
| C035207 |
4-amino-2,6-dinitrotoluene |
4-amino-2,6-dinitrotoluene affects the expression of ADCK4 mRNA | affects expression | 21346803
|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of ADCK4 mRNA | affects expression | 17562736
|
| D018038 |
Sodium Selenite |
Sodium Selenite results in increased expression of ADCK4 mRNA | increases expression | 18175754
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
4-amino-2,6-dinitrotoluene |
4.58 | 7525203 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.57 | 10982225 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
2.96 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
2.96 | 3084413 |
| MESH:D002386 |
Cataract |
|
4-amino-2,6-dinitrotoluene |
8.12 | 14694615 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
8.12 | 10977129 |
| MESH:D019457 |
Chromosome Breakage |
|
Sodium Selenite |
5.31 | 15894690 |
| MESH:D000013 |
Congenital Abnormalities |
|
4-amino-2,6-dinitrotoluene |
4.53 | 15095906 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
4.58 | 18551238 |
| MESH:D003920 |
Diabetes Mellitus |
|
Sodium Selenite |
4.15 | 16285004 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
9.81 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
4-amino-2,6-dinitrotoluene |
9.81 | 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
9.81 | 10774834 19739265 19085960 14986274 12594235 18071297 16393943 11461765 11743745 16227642 19923254 11834606 19370779 19416960 15968718 16781746 18713872 14725611 16177239 11421492 16109766 17522070 17562736 12958197 19164858 12153990 19420014 11529661 15619225 17906064 12392966 14550746 16081117 10663392 11739529 11287661 16485898 12705907 2444490 12540782 10915739 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Sodium Selenite |
9.81 | 15131321 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.82 | 19426721 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.40 | 16983495 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
3.02 | 16870215 |
| MESH:D007333 |
Insulin Resistance |
|
Sodium Selenite |
3.52 | 14714311 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.40 | 12587719 15629191 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
3.32 | 16705839 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.70 | 12587719 12969438 11587558 19460945 19784758 19014921 16611625 16610002 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.63 | 17185352 16871587 |
| MESH:D016393 |
Lymphoma, B-Cell |
|
Sodium Selenite |
4.52 | 14737004 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.13 | 19513568 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
4.49 | 18551238 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.21 | 18514411 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
10.47 | 12819281 16049721 |
| MESH:D009784 |
Occupational Diseases |
|
4-amino-2,6-dinitrotoluene |
10.47 | 14694615 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.73 | 16870215 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Sodium Selenite |
3.33 | 18760546 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
2.79 | 18551238 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
2.41 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
4.95 | 10091137 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.44 | 10982225 |
Related Pathway Information