AutismKB 2.0

Annotation Detail for PSCA


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Basic Information Top
Gene Symbol:PSCA ( PRO232 )
Gene Full Name: prostate stem cell antigen
Band: 8q24.3
Quick LinksEntrez ID:8000; OMIM: 602470; Uniprot ID:D3DWI6_HUMAN; ENSEMBL ID: ENSG00000167653; HGNC ID: 9500
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
Intestinal Neoplasms
Adenocarcinoma, Mucinous
CANCER
Carcinoma, Signet Ring Cell
bladder cancer
Carcinoma, Papillary
Adenocarcinoma
Stomach Neoplasms
Desease Name
Bladder cancer
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of PSCA mRNAincreases expression 18648102
C501474 4-OH-2',3,3',4',5'-pentachlorobiphenyl 4-OH-2',3,3',4',5'-pentachlorobiphenyl inhibits the reaction [Triiodothyronine results in increased expression of PSCA mRNA]decreases reaction|increases expression 14761676
C109238 acyline acyline results in decreased expression of PSCA mRNAdecreases expression 17510436
C501521 Akt-I-1,2 compound Akt-I-1,2 compound inhibits the reaction [Flurbiprofen results in increased expression of PSCA protein]decreases reaction|increases expression 16949054
D000638 Amiodarone Amiodarone results in decreased expression of PSCA mRNAdecreases expression 17991464
D000728 Androgens Androgens affects the expression of PSCA proteinaffects expression 16015594
D047310 Apigenin Apigenin results in decreased expression of PSCA mRNAdecreases expression 18331776
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of PSCA mRNAincreases expression 19150397
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of PSCA mRNAincreases expression 14729362
15003993
C043561 chrysin chrysin results in decreased expression of PSCA mRNAdecreases expression 18331776
D016572 Cyclosporine Cyclosporine results in decreased expression of PSCA mRNAdecreases expression 20106945
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of PSCA mRNAaffects cotreatment|increases expression 19619570
D004958 Estradiol Estradiol results in decreased expression of PSCA mRNAdecreases expression 19619570
D005480 Flurbiprofen AKT1 protein affects the reaction [Flurbiprofen results in increased expression of PSCA mRNA]affects reaction|increases expression 16949054
D005480 Flurbiprofen Akt-I-1,2 compound inhibits the reaction [Flurbiprofen results in increased expression of PSCA protein]decreases reaction|increases expression 16949054
D005480 Flurbiprofen Flurbiprofen results in increased expression of PSCA mRNAincreases expression 16949054
D005480 Flurbiprofen [Flurbiprofen results in increased phosphorylation of and results in increased activity of PSCA protein] which results in increased expression of AKT1 proteinincreases activity|increases expression|increases phosphorylation 16949054
D005480 Flurbiprofen HRAS protein affects the reaction [Flurbiprofen results in increased expression of PSCA mRNA]affects reaction|increases expression 16949054
C006552 kaempferol kaempferol results in decreased expression of PSCA mRNAdecreases expression 18331776
D047311 Luteolin Luteolin results in decreased expression of PSCA mRNAdecreases expression 19397994
18331776
C040015 myricetin myricetin results in decreased expression of PSCA mRNAdecreases expression 18331776
D011078 Polychlorinated Biphenyls Polychlorinated Biphenyls inhibits the reaction [Triiodothyronine results in increased expression of PSCA mRNA]decreases reaction|increases expression 14761676
D011794 Quercetin Quercetin results in decreased expression of PSCA mRNAdecreases expression 18331776
C009277 sodium arsenate sodium arsenate results in decreased expression of PSCA mRNAdecreases expression 12727804
C017947 sodium arsenite sodium arsenite results in decreased expression of PSCA mRNAdecreases expression 12727804
C025463 sulindac sulfone sulindac sulfone results in increased expression of PSCA mRNAincreases expression 16949054
D014284 Triiodothyronine 4-OH-2',3,3',4',5'-pentachlorobiphenyl inhibits the reaction [Triiodothyronine results in increased expression of PSCA mRNA]decreases reaction|increases expression 14761676
D014284 Triiodothyronine Polychlorinated Biphenyls inhibits the reaction [Triiodothyronine results in increased expression of PSCA mRNA]decreases reaction|increases expression 14761676
D014284 Triiodothyronine Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine results in increased expression of PSCA mRNA]increases expression|increases reaction 14761676
D014284 Triiodothyronine Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine results in increased expression of PSCA protein]increases expression|increases reaction 14761676
D014284 Triiodothyronine Triiodothyronine results in increased expression of PSCA mRNAincreases expression 14761676
D014284 Triiodothyronine Triiodothyronine results in increased expression of PSCA proteinincreases expression 14761676
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of PSCA mRNAaffects cotreatment|increases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine results in increased expression of PSCA mRNA]increases expression|increases reaction 14761676
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine results in increased expression of PSCA protein]increases expression|increases reaction 14761676
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of PSCA mRNAdecreases expression 19619570
20106945
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of PSCA mRNAincreases expression 17035482
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.7014514962 15322242 11752688
MESH:D000230 Adenocarcinoma Estradiol 2.0611473722
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.673712494
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.2316835633
MESH:D011125 Adenomatous Polyposis Coli Flurbiprofen 10.1310680582
MESH:D011125 Adenomatous Polyposis Coli sulindac sulfone 10.1316150858
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.5515276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.7516712894 17306315
MESH:D000544 Alzheimer Disease Androgens 3.5817917157 17182789
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8111748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.1017084956
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.6718057881 18218290 20041841
MESH:D001260 Ataxia Telangiectasia Quercetin 4.8215336622
MESH:D001281 Atrial Fibrillation Amiodarone 3.7918651412 19698954
MESH:D001327 Autoimmune Diseases Quercetin 4.2619761891
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.871440618 11289319
MESH:D001778 Blood Coagulation Disorders Amiodarone 8.5819483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.5812125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6415340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6715746008
MESH:D001943 Breast Neoplasms Androgens 2.9117018787
MESH:D001943 Breast Neoplasms Apigenin 2.9117132221 16541309
MESH:D001943 Breast Neoplasms Estradiol 2.9117289903 18497071 12948864 14630087 17018787 19861407 17261762 16675129
MESH:D001943 Breast Neoplasms kaempferol 2.9116756079
MESH:D001943 Breast Neoplasms Quercetin 2.9118628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.9120435547
MESH:D002105 Cadmium Poisoning Quercetin 5.3916962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.3116111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6816835633
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 6.393581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Estradiol 6.3916924424
MESH:D006528 Carcinoma, Hepatocellular Quercetin 6.3919519916 12508355
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 6.3915276417 17306315 16507464
MESH:D002289 Carcinoma, Non-Small-Cell Lung sulindac sulfone 4.0318758305
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.8017234771
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.617296757
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 2.3418572023
MESH:D006332 Cardiomegaly Quercetin 6.5319794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.5316120746 18850075 18670907
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.8419225199 15710769
MESH:D002318 Cardiovascular Diseases kaempferol 4.2916756079
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.9318974383
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 19.987505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 19.9820889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 19.9812371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 19.9818566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 19.9819524636 20056578
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0316835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 7.509022650 19486331
MESH:D002779 Cholestasis Cyclosporine 7.5019486331
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0415340226 8697196 16354765 12621046 15668235
MESH:D003110 Colonic Neoplasms Quercetin 2.4015741050 19056647 11134977 17148506 16640504 19440933 17191121
MESH:D015179 Colorectal Neoplasms Polychlorinated Biphenyls 3.7115531428
MESH:D015179 Colorectal Neoplasms Quercetin 3.7118852136 18095365
MESH:D015179 Colorectal Neoplasms sulindac sulfone 3.7110416599 11197048 10666051 18059344
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9314669216 17141729
MESH:D019465 Craniofacial Abnormalities sodium arsenate 2.7310525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.7310048152 20055451 15322242
MESH:D016638 Critical Illness Androgens 5.9116670151
MESH:D003704 Dementia Polychlorinated Biphenyls 4.5616140633
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.6611906362 8156756 12868966 18759878 11298694 8970840 2524372 14531868
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.352952479 3621924
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.6119496084
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6317107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.2819279558
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 8.6518289764 9328219 6482804 1440618 11289319 16192314 9653073 7440962 18692083 8291058 18648102 9022650 6679447
MESH:D056486 Drug-Induced Liver Injury Amiodarone 8.6518218290 15265979
MESH:D056486 Drug-Induced Liver Injury sodium arsenate 8.6518186108
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 8.6520420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6511462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.2412711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7518230668 15322242 16714409
MESH:D016889 Endometrial Neoplasms Estradiol 2.8818566989 11473722 19148513
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.8910568697 9294722
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 4.253581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.2520426865
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9011564622
MESH:D005234 Fatty Liver Amiodarone 7.3814986274
MESH:D005234 Fatty Liver Cyclosporine 7.3819224547
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3111858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.876705139
MESH:D005355 Fibrosis Cyclosporine 13.9012639820 12168785
MESH:D005355 Fibrosis Quercetin 13.9019474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 13.9020067830
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.5316452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.078708960
MESH:D005909 Glioblastoma myricetin 7.5419804834
MESH:D005909 Glioblastoma Quercetin 7.5419804834
MESH:D005910 Glioma Quercetin 3.0017643826
MESH:D018149 Glucose Intolerance sodium arsenate 4.9419446573
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.897505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4410696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2511294989 10048152
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2715720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2011000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.376705139
MESH:D006529 Hepatomegaly Amiodarone 8.0415265979
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.0416120746 15340226 12621046
MESH:D006558 Herpes Genitalis Estradiol 4.8815709030
MESH:D006628 Hirsutism Androgens 5.9316914592 17019078
MESH:D006689 Hodgkin Disease sodium arsenite 3.0312676792
MESH:D019584 Hot Flashes Estradiol 3.6017088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8916354765 15340226 16959395 8697196 18606429
MESH:D017588 Hyperandrogenism Androgens 5.5817019078
MESH:D006937 Hypercholesterolemia Amiodarone 3.739751232 8137927
MESH:D006943 Hyperglycemia kaempferol 9.4618262572
MESH:D006943 Hyperglycemia Quercetin 9.4618262572 11834736
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.7915034207
MESH:D006973 Hypertension Cyclosporine 8.2410903974
MESH:D006973 Hypertension Quercetin 8.2418356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.2418850075 18670907
MESH:D007037 Hypothyroidism Amiodarone 4.3617991464 18020914
MESH:D007248 Infertility, Male sodium arsenite 2.8912646999 15346721
MESH:D007249 Inflammation Flurbiprofen 5.1511099482
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 5.1512200463 12878042
MESH:D007251 Influenza, Human Quercetin 4.3616624496
MESH:D007333 Insulin Resistance Estradiol 2.8716393666 16627594
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.879022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2016580747
MESH:D007627 Keloid Quercetin 4.8017086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2915604871
MESH:D007674 Kidney Diseases Cyclosporine 13.758314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 13.7515618244
MESH:D007674 Kidney Diseases Quercetin 13.7516962696
MESH:D007674 Kidney Diseases sodium arsenite 13.7520008137
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 11.646582329
MESH:D007680 Kidney Neoplasms Cyclosporine 11.6412371664
MESH:D007680 Kidney Neoplasms Estradiol 11.6415610895
MESH:D007938 Leukemia kaempferol 6.7117468513
MESH:D007938 Leukemia Quercetin 6.7117468513
MESH:D008039 Linitis Plastica marker/mechanism 18488030
MESH:D008064 Lipidoses Amiodarone 3.4015342952 17567588
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.1015034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 3.3914716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 3.3912741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.3912878042
MESH:D008113 Liver Neoplasms Quercetin 7.1418980244
MESH:D008113 Liver Neoplasms sodium arsenite 7.1415276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 7.1416984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 13.403712494 598648 6587162 1399818
MESH:D008114 Liver Neoplasms, Experimental Polychlorinated Biphenyls 13.401423854
MESH:D008114 Liver Neoplasms, Experimental Quercetin 13.4019519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.4012151625
MESH:D008133 Long QT Syndrome Amiodarone 3.4611989578 15350150 17391786
MESH:D008171 Lung Diseases Amiodarone 7.1812587719
MESH:D008171 Lung Diseases sodium arsenite 7.1819095001
MESH:D017563 Lung Diseases, Interstitial Amiodarone 4.3318516814
MESH:D008175 Lung Neoplasms Quercetin 3.3516280456
MESH:D008175 Lung Neoplasms sodium arsenite 3.3515276417 17077188 16712894 19931552 17306315
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.3511884234 19555203
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.4711807958 17203775 16891317 11408345
MESH:D020149 Manganese Poisoning Estradiol 4.3319453300
MESH:D008545 Melanoma sodium arsenite 2.0116487513 19082730
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6416801185
MESH:D009139 Musculoskeletal Abnormalities sodium arsenate 4.7218186108
MESH:D009181 Mycoses Amiodarone 4.7512754197 17974566
MESH:D009203 Myocardial Infarction Quercetin 2.9319595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9012213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.1716810080
MESH:D015428 Myocardial Reperfusion Injury Quercetin 8.1719207477
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.413581430
MESH:D009369 Neoplasms Quercetin 5.0115185748
MESH:D009369 Neoplasms sodium arsenite 5.0111559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.5220056578
MESH:D009389 Neovascularization, Pathologic Estradiol 3.5817289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2917954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1518481113 19348381
MESH:D009421 Nervous System Malformations Estradiol 8.9716427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.9714600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 11.686679447
MESH:D009436 Neural Tube Defects sodium arsenate 11.6810525206 18186108 11749123 19446573
MESH:D009436 Neural Tube Defects sodium arsenite 11.6812854658
MESH:D020078 Neurogenic Inflammation Quercetin 4.2217929310
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.294026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.873988306
MESH:D010024 Osteoporosis kaempferol 4.2616756079
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.0819495926
MESH:D010051 Ovarian Neoplasms Estradiol 10.9819401270
MESH:D010051 Ovarian Neoplasms Luteolin 10.9819005980
MESH:D010051 Ovarian Neoplasms Quercetin 10.9819005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 10.9815276417 17306315
MESH:D010190 Pancreatic Neoplasms Quercetin 2.8016965848
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.337296757
MESH:D010300 Parkinson Disease Polychlorinated Biphenyls 3.3416702228
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1012520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.326228378
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4118163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.6712371664
MESH:D011230 Precancerous Conditions Quercetin 8.6719056647
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.0411896295 11118676 11399792 11222880
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.7520887781
MESH:D011471 Prostatic Neoplasms marker/mechanism 16015594
MESH:D011471 Prostatic Neoplasms Androgens 2.4315389811 16998812 17909013
MESH:D011471 Prostatic Neoplasms Apigenin 2.4317132221
MESH:D011471 Prostatic Neoplasms Estradiol 2.4316740699
MESH:D011471 Prostatic Neoplasms Flurbiprofen 2.4317409433
MESH:D011471 Prostatic Neoplasms Polychlorinated Biphenyls 2.4315721890
MESH:D011471 Prostatic Neoplasms Quercetin 2.4314715546 17292933
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.4316039940
MESH:D011471 Prostatic Neoplasms sulindac sulfone 2.4315570007 17908994
MESH:D011565 Psoriasis Cyclosporine 2.1816882103
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.8011597910 12832656 12490602
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6918990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.263692021
MESH:D012554 Schistosomiasis japonica Quercetin 5.3916862918
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.9318724381
MESH:D012878 Skin Neoplasms sodium arsenite 9.0318572023 19524636
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 9.038532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.0316192470
MESH:D016135 Spinal Dysraphism sodium arsenite 3.6812854658
MESH:D013274 Stomach Neoplasms marker/mechanism 18488030
MESH:D013276 Stomach Ulcer Amiodarone 3.1818087811
MESH:D013610 Tachycardia Amiodarone 4.1411238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.0419225199
MESH:D013959 Thyroid Diseases Amiodarone 11.5519731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 11.5512697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 2.776587162 6582329 7505956 3712494 1399818
MESH:D013971 Thyrotoxicosis Amiodarone 4.7119584973 18020914
MESH:D013978 Tibial Fractures Estradiol 4.5319048282
MESH:D016171 Torsades de Pointes Amiodarone 4.0417467628 11989578
MESH:D001749 Urinary Bladder Neoplasms marker/mechanism 19648920
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 8.038074119
MESH:D001749 Urinary Bladder Neoplasms Quercetin 8.0316720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 8.0316712894 17306315 11723127 16452187
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.6311813266
MESH:D014605 Uveitis Cyclosporine 3.831336536
MESH:D014652 Vascular Diseases sodium arsenite 4.2717056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4412125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1015886252
MESH:D014985 Xerophthalmia Cyclosporine 4.2917120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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