Gene Symbol:	PHC3 ( DKFZp313K1221,EDR3,FLJ12729,FLJ12967,HPH3,MGC88144 )
Gene Full Name:	polyhomeotic homolog 3 (Drosophila)
Band:	3q26.2
Quick Links	Entrez ID:80012; OMIM: NA; Uniprot ID:PHC3_HUMAN; ENSEMBL ID: ENSG00000173889; HGNC ID: 15682
Relate to Another Database:	SFARIGene; denovo-db

Chemical ID	Chemical Name	Interaction	Interaction Action	Publication
D017638	Asbestos, Crocidolite	Asbestos, Crocidolite results in increased expression of PHC3 mRNA	increases expression	18687144
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of PHC3 mRNA	decreases expression	19150397
D018038	Sodium Selenite	Sodium Selenite results in decreased expression of PHC3 mRNA	decreases expression	18175754

Disease ID	Disease Name	Inference Chemical Name	Inference Score	Publication
MESH:D002471	Cell Transformation, Neoplastic	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	3.01	20889678
MESH:D019457	Chromosome Breakage	Sodium Selenite	5.41	15894690
MESH:D003920	Diabetes Mellitus	Sodium Selenite	4.19	16285004
MESH:D056486	Drug-Induced Liver Injury	Sodium Selenite	2.37	15131321
MESH:D004938	Esophageal Neoplasms	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	2.15	20426865
MESH:D007333	Insulin Resistance	Sodium Selenite	3.54	14714311
MESH:D055370	Lung Injury	Asbestos, Crocidolite	4.67	17365036
MESH:D016393	Lymphoma, B-Cell	Sodium Selenite	4.59	14737004
MESH:D008654	Mesothelioma	Asbestos, Crocidolite	3.32	16166281 16966607 18303189
MESH:D010995	Pleural Diseases	Asbestos, Crocidolite	5.55	10923243
MESH:D011471	Prostatic Neoplasms	Sodium Selenite	3.33	18760546
MESH:D011658	Pulmonary Fibrosis	Asbestos, Crocidolite	3.16	17975199 17365031 17322281 15814490

AutismKB 2.0

Annotation Detail for PHC3