AutismKB 2.0

Annotation Detail for NAA25


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Basic Information Top
Gene Symbol:NAA25 ( C12orf30,DKFZp667K2112,FLJ13089,MDM20,NAP1 )
Gene Full Name: N(alpha)-acetyltransferase 25, NatB auxiliary subunit
Band: 12q24.13
Quick LinksEntrez ID:80018; OMIM: 612755; Uniprot ID:NAA25_HUMAN; ENSEMBL ID: ENSG00000111300; HGNC ID: 25783
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Desease IDDesease Name
Metabolic diseases
Diabetes
H00408Type I diabetes mellitus
No data
Desease Name
type 1 diabetes
IMMUNE
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of NAA25 mRNAdecreases expression 19150397
D016572 Cyclosporine Cyclosporine results in increased expression of NAA25 mRNAincreases expression 20106945
C011890 kojic acid kojic acid results in increased expression of NAA25 mRNAincreases expression 16595896
D014635 Valproic Acid Valproic Acid results in decreased expression of NAA25 mRNAdecreases expression 19101580
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 4.118875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.3519490988
MESH:D000550 Amblyopia Valproic Acid 5.9617688650
MESH:D001008 Anxiety Disorders Valproic Acid 3.9017497229
MESH:D001321 Autistic Disorder Valproic Acid 1.9816609825 18985861 19460635 18558336 18775368 18940202 17688650 17507914 18316065 20603192 17157402 15238991 19232924 18177632 18396377
MESH:D001714 Bipolar Disorder Valproic Acid 3.2417594078 20046352
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.638888407
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.4420889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.4412371664
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.8220734317
MESH:D002779 Cholestasis Cyclosporine 3.2119486331
MESH:D019465 Craniofacial Abnormalities Valproic Acid 1.918888407 17688650 16575769
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 2.2519641884 1733752
MESH:D004421 Dystonia Valproic Acid 4.511851702
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.7117275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 4.643922381 16628512
MESH:D004827 Epilepsy Valproic Acid 3.1118234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 3.967562514 6254150 6426943
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.867750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.693659116
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1520426865
MESH:D005234 Fatty Liver Cyclosporine 9.2019224547
MESH:D005234 Fatty Liver Valproic Acid 9.2019224547 14986274
MESH:D005315 Fetal Diseases Valproic Acid 5.6116575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.648888407 18558336
MESH:D005355 Fibrosis Cyclosporine 3.7012639820 12168785
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.858708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.0515720958
MESH:D006849 Hydrocephalus Valproic Acid 5.5017688650
MESH:D006973 Hypertension Cyclosporine 2.2110903974
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.1615604871
MESH:D007674 Kidney Diseases Cyclosporine 2.548314463 18776723 10903974
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0812371664
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.2016294345 17596541
MESH:D008114 Liver Neoplasms, Experimental kojic acid 3.5518544905
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.9817228818
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.5116801185
MESH:D008881 Migraine Disorders Valproic Acid 3.4718765137 18803445
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.458888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3517596541
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.1617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6518481113 19348381
MESH:D009436 Neural Tube Defects Valproic Acid 3.378888407 16359493
MESH:D011230 Precancerous Conditions Cyclosporine 3.5912371664
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 4.4620603192
MESH:D019310 Pseudolymphoma Valproic Acid 5.2612752131 11422049
MESH:D011565 Psoriasis Cyclosporine 2.3316882103
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.6419155313
MESH:D012559 Schizophrenia Valproic Acid 2.1019110320 15737665
MESH:D012640 Seizures Valproic Acid 2.9917978042 14763951 11738929 1511512 16876388 3137016 15475178 11044598
MESH:D016135 Spinal Dysraphism Valproic Acid 4.0919490988
MESH:D013226 Status Epilepticus Valproic Acid 5.2612833885
MESH:D014178 Translocation, Genetic Valproic Acid 5.9617262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 5.153119515
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.208888407
MESH:D014605 Uveitis Cyclosporine 4.711336536
MESH:D014985 Xerophthalmia Cyclosporine 5.1617120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA143485360
    • No data
    Releated disease ID Related disease Name
    PA443888Diabetes Mellitus, Type 1
    PA443886Diabetes Mellitus
    PA443888Diabetes Mellitus, Type 1
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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