AutismKB 2.0

Annotation Detail for VCPIP1


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Basic Information Top
Gene Symbol:VCPIP1 ( DKFZp686G038,DUBA3,FLJ23132,FLJ60694,KIAA1850,VCIP135 )
Gene Full Name: valosin containing protein (p97)/p47 complex interacting protein 1
Band: 8q13.1
Quick LinksEntrez ID:80124; OMIM: 611745; Uniprot ID:VCIP1_HUMAN; ENSEMBL ID: ENSG00000175073; HGNC ID: 30897
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of VCPIP1 mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of VCPIP1 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of VCPIP1 mRNAincreases expression 20458559
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of VCPIP1 mRNAincreases expression 20064835
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of VCPIP1 mRNAaffects cotreatment|decreases expression 20360939
D003010 Clorgyline Clorgyline results in increased expression of VCPIP1 mRNAincreases expression 19691856
D004051 Diethylhexyl Phthalate Diethylhexyl Phthalate results in decreased expression of VCPIP1 proteindecreases expression 16400681
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of VCPIP1 mRNAaffects cotreatment|decreases expression 20360939
D014415 Tunicamycin Tunicamycin results in increased expression of VCPIP1 mRNAincreases expression 17127020
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Diethylhexyl Phthalate 4.856734493
MESH:D000138 Acidosis Ammonium Chloride 3.8418287403
MESH:D000230 Adenocarcinoma arsenic trioxide 4.5019825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.5020127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 7.006695378
MESH:D000236 Adenoma Diethylnitrosamine 7.006695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 4.1817162532 19052882 18056438 16434500 17620307 19061943
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.3319183758
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 3.8816206674
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0720146248 17474063
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.0717474063
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.5511589617
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 4.7516705839
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 4.7516217749 11135700 15073043 14691202 15553829
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 4.7520514400 20101231 17055752 3581430 16569478 17978847 18788625 20935162 16502159 20007298 16830150 16288022 18978308 20524982 16878318 17173139 16328049 19519916 16540662 19107877 10672840 19383236 16935385 20084675 20727157 19539802 19919837 19394651 19208518 17428255 20214788 19171122 20512989 18056438 16698587 19335982 16681979 16807293 20432363 18691550 18971187 17138121 19701751 18665156 18210153 19052882 21159647 18494052 10737359 3084413 19418558 16779866 18393292 18506893 11831363 18785209 19822196 17162532 17761372
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.1919014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.3112490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1020419170
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 7.156135515
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 7.157505956 2727394 21159647 17174075
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.8719052882
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.4212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8910525206
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.2818551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.3215213294
MESH:D003876 Dermatitis, Atopic Diethylhexyl Phthalate 4.1316882537
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.2320387270
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 4.0618551238 21346803
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 4.0619107877
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.4416302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.5912903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.5916530937
MESH:D005234 Fatty Liver arsenic trioxide 8.5715073043
MESH:D005234 Fatty Liver Diethylnitrosamine 8.5721071580 20387270
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.5016904648
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.7520471113
MESH:D007249 Inflammation Diethylnitrosamine 2.4718785209
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 4.7810783313
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 3.6515369732
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.1516705839
MESH:D007938 Leukemia arsenic trioxide 2.9215070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.0012560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.5916972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.5814633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.9719077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1620471514 19850784 17050201 16467208 16968895
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 8.3719225113 19075265 12679006 9834237 16823087 19642359 11161223 16112521 15622746 17712046 16966277 16331271 17649720 11468182 17869043 15748426 15336539 12712474 12018890 15213294 16891316 17107899 16330433 17217047 19035177
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 8.3716766008
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.5916882451
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.9320032147 19638242 18522880 18407596 18665156
MESH:D008107 Liver Diseases Diethylnitrosamine 2.1417034775
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 15.017678174
MESH:D008113 Liver Neoplasms arsenic trioxide 15.0114682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 15.0121137059 20195826
MESH:D008113 Liver Neoplasms Diethylhexyl Phthalate 15.0111940454
MESH:D008113 Liver Neoplasms Diethylnitrosamine 15.0118977376 19427195 19255062 19642983 20101389 19638242 18648771 18978307 19996281 16942905 20434301 20118626 15175105 18644402 20583210 9163691 19850985 12771043 19254457 19690152 21167192 18754104 19294768 12112319 20137499 20492335 19833225 10737359 19499222 2422723 15885732 19090486 20452335 2862719 20405173 19812893 21278145 19256749 19426721 19073162 21047994 19551842 20501860 21071580
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 10.582876786 2876784 6135515
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 10.5820377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 10.5818079962 17854601 17942915 16267830 21159647 19009564 18253720 18308698 19126423 16842330 17174075 18282651 19519916 19539802 18544905 18164116 19004024 18093689 18775883 9362446 2563599 3124819
MESH:D008133 Long QT Syndrome arsenic trioxide 3.5115213294
MESH:D008175 Lung Neoplasms arsenic trioxide 3.5419825857 11798837
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 3.5420869020 20464547 20064080 17053015 18569708 18816296 20135361 18520028 6695378
MESH:D008175 Lung Neoplasms Diethylnitrosamine 3.5420970405 6695378 21163286 20512841
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.3516381670
MESH:D009101 Multiple Myeloma arsenic trioxide 3.2514977855 19549372 19417148 11468182 15949261
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.9918349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.2516105982 16882451
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.1518551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.2016624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.643581430 9029167
MESH:D009369 Neoplasms Benzo(a)pyrene 2.2511141357
MESH:D009436 Neural Tube Defects arsenic trioxide 3.2410525206
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.5120387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.4420387270
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.6216049721
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.4619769630 12452020 16624393
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 5.4915580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.4916540662
MESH:D010235 Paraganglioma arsenic trioxide 4.3819927285
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.732563599
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.6519131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.6517292933
MESH:D011471 Prostatic Neoplasms Clorgyline 2.6519691856
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.2016646077
MESH:D012640 Seizures 2,6-dinitrotoluene 2.6718551238
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.4510029692 19755658
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.4217007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.422093021 20155912
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.4218456281
MESH:D013964 Thyroid Neoplasms arsenic trioxide 7.7219014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 7.727505956
MESH:D016171 Torsades de Pointes arsenic trioxide 4.2415213294
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 8.7016049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.7011780464 12845720 20435036 12973940
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 8.7017053015
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.6010091137
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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