Gene Symbol:	DBF4B ( ASKL1,CHIFB,DRF1,FLJ13087,MGC15009,ZDBF1B )
Gene Full Name:	DBF4 homolog B (S. cerevisiae)
Band:	17q21.31
Quick Links	Entrez ID:80174; OMIM: 611661; Uniprot ID:DBF4B_HUMAN; ENSEMBL ID: ENSG00000161692; HGNC ID: 17883
Relate to Another Database:	SFARIGene; denovo-db

Chemical ID	Chemical Name	Interaction	Interaction Action	Publication
D006830	Hydralazine	[Hydralazine co-treated with Valproic Acid] results in increased expression of DBF4B mRNA	affects cotreatment\|increases expression	17183730
D018038	Sodium Selenite	Sodium Selenite results in decreased expression of DBF4B mRNA	decreases expression	18175754
D014635	Valproic Acid	[Hydralazine co-treated with Valproic Acid] results in increased expression of DBF4B mRNA	affects cotreatment\|increases expression	17183730

Disease ID	Disease Name	Inference Chemical Name	Inference Score	Publication
MESH:D000014	Abnormalities, Drug-Induced	Valproic Acid	4.23	8875741
MESH:D000015	Abnormalities, Multiple	Valproic Acid	4.41	19490988
MESH:D000550	Amblyopia	Valproic Acid	6.10	17688650
MESH:D001008	Anxiety Disorders	Valproic Acid	3.94	17497229
MESH:D001321	Autistic Disorder	Valproic Acid	1.98	18177632 17688650 20603192 19232924 15238991 17507914 18316065 18940202 18985861 16609825 18558336 18396377 19460635 17157402 18775368
MESH:D001714	Bipolar Disorder	Valproic Acid	3.26	17594078 20046352
MESH:D001848	Bone Diseases, Developmental	Valproic Acid	3.66	8888407
MESH:D002659	Child Development Disorders, Pervasive	Valproic Acid	2.83	20734317
MESH:D019457	Chromosome Breakage	Sodium Selenite	5.41	15894690
MESH:D019465	Craniofacial Abnormalities	Valproic Acid	1.91	16575769 17688650 8888407
MESH:D003920	Diabetes Mellitus	Sodium Selenite	4.19	16285004
MESH:D056486	Drug-Induced Liver Injury	Sodium Selenite	4.38	15131321
MESH:D056486	Drug-Induced Liver Injury	Valproic Acid	4.38	1733752 19641884
MESH:D004421	Dystonia	Valproic Acid	4.58	1851702
MESH:D004831	Epilepsies, Myoclonic	Valproic Acid	4.81	17275665 3659116
MESH:D004828	Epilepsies, Partial	Valproic Acid	4.78	3922381 16628512
MESH:D004827	Epilepsy	Valproic Acid	3.12	20417680 18234410
MESH:D004832	Epilepsy, Absence	Valproic Acid	4.00	6254150 7562514 6426943
MESH:D017029	Epilepsy, Complex Partial	Valproic Acid	4.95	7750514
MESH:D004830	Epilepsy, Tonic-Clonic	Valproic Acid	4.81	3659116
MESH:D005234	Fatty Liver	Valproic Acid	3.78	19224547 14986274
MESH:D005315	Fetal Diseases	Valproic Acid	5.75	16575769
MESH:D005317	Fetal Growth Retardation	Valproic Acid	4.71	8888407 18558336
MESH:D006849	Hydrocephalus	Valproic Acid	5.61	17688650
MESH:D046110	Hypertension, Pregnancy-Induced	Hydralazine	5.28	16612254
MESH:D007333	Insulin Resistance	Sodium Selenite	3.54	14714311
MESH:D015470	Leukemia, Myeloid, Acute	Valproic Acid	2.20	16294345 17596541
MESH:D017563	Lung Diseases, Interstitial	Valproic Acid	5.13	17228818
MESH:D016393	Lymphoma, B-Cell	Sodium Selenite	4.59	14737004
MESH:D008881	Migraine Disorders	Valproic Acid	3.50	18765137 18803445
MESH:D009139	Musculoskeletal Abnormalities	Valproic Acid	4.51	8888407
MESH:D009190	Myelodysplastic Syndromes	Valproic Acid	3.37	17596541
MESH:D009436	Neural Tube Defects	Valproic Acid	3.39	16359493 8888407
MESH:D011297	Prenatal Exposure Delayed Effects	Valproic Acid	4.57	20603192
MESH:D011471	Prostatic Neoplasms	Sodium Selenite	3.33	18760546
MESH:D019310	Pseudolymphoma	Valproic Acid	5.41	11422049 12752131
MESH:D012208	Rhabdomyosarcoma	Valproic Acid	4.70	19155313
MESH:D012559	Schizophrenia	Valproic Acid	2.11	19110320 15737665
MESH:D012640	Seizures	Valproic Acid	3.02	1511512 17978042 11044598 16876388 14763951 15475178 3137016 11738929
MESH:D016135	Spinal Dysraphism	Valproic Acid	4.13	19490988
MESH:D013226	Status Epilepticus	Valproic Acid	5.41	12833885
MESH:D014178	Translocation, Genetic	Valproic Acid	6.10	17262798
MESH:D020194	Unverricht-Lundborg Syndrome	Valproic Acid	5.26	3119515
MESH:D014564	Urogenital Abnormalities	Valproic Acid	5.30	8888407

AutismKB 2.0

Annotation Detail for DBF4B

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics