Annotation Detail for SPG11
Basic Information Top
| Gene Symbol: | SPG11 ( DKFZp762B1512,FLJ21439,KIAA1840 ) |
|---|---|
| Gene Full Name: | spastic paraplegia 11 (autosomal recessive) |
| Band: | 15q21.1 |
| Quick Links | Entrez ID:80208; OMIM: 610844; Uniprot ID:SPTCS_HUMAN; ENSEMBL ID: ENSG00000104133; HGNC ID: 11226 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of SPG11 mRNA | affects expression | 17562736 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 5.26 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.86 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.69 | 19416960 17562736 15968718 17906064 18071297 16485898 14986274 19739265 17522070 2444490 11461765 19923254 12958197 10663392 16227642 14550746 19085960 11743745 16109766 12705907 12392966 12153990 19420014 19164858 16081117 11739529 11834606 16393943 11421492 11529661 16177239 11287661 10774834 18713872 10915739 12594235 16781746 14725611 15619225 19370779 12540782 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 5.51 | 19426721 | |
| MESH:D005756 | Gastritis | Acetaminophen | 5.09 | 16983495 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.15 | 16870215 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.47 | 12587719 15629191 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.72 | 12969438 19784758 16611625 11587558 12587719 19014921 16610002 19460945 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.81 | 17185352 16871587 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.47 | 19513568 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.36 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.87 | 16870215 | |
| MESH:C537483 | Spastic paraplegia 11, autosomal recessive | marker/mechanism | |||
| MESH:D014581 | Urticaria | Acetaminophen | 3.67 | 10982225 |
| No data |