AutismKB 2.0

Annotation Detail for ARMC9


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Basic Information Top
Gene Symbol:ARMC9 ( ARM,FLJ12584,KU-MEL-1 )
Gene Full Name: armadillo repeat containing 9
Band: 2q37.1
Quick LinksEntrez ID:80210; OMIM: NA; Uniprot ID:ARMC9_HUMAN; ENSEMBL ID: ENSG00000135931; HGNC ID: 20730
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of ARMC9 mRNAincreases expression 19933214
D000638 Amiodarone Amiodarone results in increased expression of ARMC9 mRNAincreases expression 19774075
C006632 arsenic trioxide arsenic trioxide results in decreased expression of ARMC9 mRNAdecreases expression 15761015
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of ARMC9 mRNAincreases expression 20064835
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ARMC9 mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of ARMC9 mRNAincreases expression 18301758
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of ARMC9 mRNAincreases expression 20106945
D014501 Uranium Uranium results in increased expression of ARMC9 mRNAincreases expression 15672453
C005460 uranyl acetate uranyl acetate results in increased expression of ARMC9 mRNAincreases expression 15672453
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.1814514962 15322242 11752688
MESH:D055371 Acute Lung Injury pirinixic acid 3.3818653653
MESH:D000230 Adenocarcinoma arsenic trioxide 4.5219825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.5220127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.786695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 11.0516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 11.0516835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.1711748828
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.3819183758
MESH:D001145 Arrhythmias, Cardiac Amiodarone 4.0320041841 18057881 18218290
MESH:D001281 Atrial Fibrillation Amiodarone 4.0819698954 18651412
MESH:D001778 Blood Coagulation Disorders Amiodarone 24.0819483382
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 24.0816206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 24.0819483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 24.0812125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.1715340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.9115746008
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.8720146248 17474063
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.8720435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.5911589617
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.9916835633
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 1.9715073043 15553829 11135700 16217749 14691202
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.2519014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.3512490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1020419170
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4918850075 18670907 16120746
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.9619225199 15710769
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.4218974383
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.3816835633
MESH:D002779 Cholestasis pirinixic acid 3.0019176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1915340226 8697196 12621046 15668235 16354765
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.2714669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 4.4712609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.5310525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.5310048152 15322242 20055451
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.3615213294
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5218249437
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7117107852
MESH:D056486 Drug-Induced Liver Injury Amiodarone 4.0515265979 18218290
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 4.0520420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.9311462148
MESH:D004487 Edema pirinixic acid 7.3512083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 7.3512711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.2815322242 16714409 18230668
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.2510568697 9294722
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.6112903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.6116530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.1911564622
MESH:D005234 Fatty Liver Amiodarone 14.6114986274
MESH:D005234 Fatty Liver arsenic trioxide 14.6115073043
MESH:D005234 Fatty Liver pirinixic acid 14.6120131406 19236843
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.7611858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.2520067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.5416904648
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.9710696789
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.8220471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.8210048152 11294989
MESH:D006333 Heart Failure pirinixic acid 2.6720558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.5811000095
MESH:D006529 Hepatomegaly Amiodarone 16.2915265979
MESH:D006529 Hepatomegaly pirinixic acid 16.2918467677 16221962 19176532 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 16.2915340226 12621046 16120746
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.4215340226 18606429 16354765 8697196 16959395
MESH:D006937 Hypercholesterolemia Amiodarone 4.128137927 9751232
MESH:D006943 Hyperglycemia pirinixic acid 3.4120558911
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9818850075 18670907
MESH:D007037 Hypothyroidism Amiodarone 4.8218020914 17991464
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.9612878042 12200463
MESH:D007333 Insulin Resistance pirinixic acid 2.7816306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.5816580747
MESH:D007938 Leukemia arsenic trioxide 2.9315070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.0412560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.6416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.6014633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.0019077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1717050201 16968895 20471514 19850784 16467208
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.3615622746 17107899 17869043 16112521 15336539 11468182 16331271 19075265 16330433 17649720 9834237 16823087 12018890 19035177 15748426 19642359 12712474 16966277 17217047 19225113 17712046 16891316 12679006 15213294 11161223
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.6316882451
MESH:D008064 Lipidoses Amiodarone 3.6815342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.1915474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.1912878042
MESH:D008113 Liver Neoplasms arsenic trioxide 11.3314682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 11.3321137059 20195826
MESH:D008113 Liver Neoplasms pirinixic acid 11.3316377806 15890375 20007298
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 11.3316984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 6.2720377131
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 6.2712151625
MESH:D008133 Long QT Syndrome Amiodarone 8.8115350150 11989578 17391786
MESH:D008133 Long QT Syndrome arsenic trioxide 8.8115213294
MESH:D008171 Lung Diseases Amiodarone 3.5312587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 4.8518516814
MESH:D008175 Lung Neoplasms arsenic trioxide 3.4819825857 11798837
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 3.4818569708 20135361 17053015 18816296 20464547 20869020 18520028 20064080 6695378
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.4819555203 11884234
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.3716381670
MESH:D009101 Multiple Myeloma arsenic trioxide 3.2715949261 19549372 14977855 11468182 19417148
MESH:D009135 Muscular Diseases pirinixic acid 3.8116239165
MESH:D009181 Mycoses Amiodarone 5.2812754197 17974566
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.0518349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.2616882451 16105982
MESH:D009203 Myocardial Infarction pirinixic acid 2.2219151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.2112213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1316411023
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.2416624393
MESH:D009369 Neoplasms Benzo(a)pyrene 5.1711141357
MESH:D009369 Neoplasms pirinixic acid 5.1717405874
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.4914600291
MESH:D009436 Neural Tube Defects arsenic trioxide 3.2610525206
MESH:D009765 Obesity pirinixic acid 1.8620558911
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.4712452020 16624393 19769630
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.5915580305
MESH:D010235 Paraganglioma arsenic trioxide 4.4219927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.6212520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.8418163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.5311896295 11222880 11399792 11118676
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.1219131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.1217292933
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.9311597910 12832656 12490602
MESH:D015427 Reperfusion Injury pirinixic acid 2.4919058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.1218990726
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.2416646077
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.4218724381
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.8019755658 10029692
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.8016192470
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.4217007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.4220155912 2093021
MESH:D013276 Stomach Ulcer Amiodarone 3.5518087811
MESH:D013610 Tachycardia Amiodarone 4.5711238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.4719225199
MESH:D013959 Thyroid Diseases Amiodarone 13.3419731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 13.3412697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.2719014326
MESH:D013971 Thyrotoxicosis Amiodarone 5.1719584973 18020914
MESH:D016171 Torsades de Pointes Amiodarone 11.4117467628 11989578
MESH:D016171 Torsades de Pointes arsenic trioxide 11.4115213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 5.3120435036 12973940 11780464 12845720
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.3117053015
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.9712125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.6215886252
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA142672581
    • No data
    Releated disease ID Related disease Name
    PA444119Eye Diseases
    PA446225Eye Diseases, Hereditary
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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