AutismKB 2.0

Annotation Detail for WDR26


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Basic Information Top
Gene Symbol:WDR26 ( CDW2,FLJ21016,MIP2 )
Gene Full Name: WD repeat domain 26
Band: 1q42.11-q42.12
Quick LinksEntrez ID:80232; OMIM: NA; Uniprot ID:WDR26_HUMAN; ENSEMBL ID: ENSG00000162923; HGNC ID: 21208
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of WDR26 mRNAaffects expression 17562736
D000638 Amiodarone Amiodarone affects the expression of WDR26 mRNAaffects expression 19483382
D001151 Arsenic Arsenic affects the expression of WDR26 mRNAaffects expression 18414638
D001553 Benzbromarone Benzbromarone affects the expression of WDR26 mRNAaffects expression 19483382
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of WDR26 mRNAincreases expression 15336504
D002994 Clofibrate Clofibrate affects the expression of WDR26 mRNAaffects expression 19483382
D005001 Ethionine Ethionine affects the expression of WDR26 mRNAaffects expression 19483382
D009853 Omeprazole Omeprazole affects the expression of WDR26 mRNAaffects expression 19483382
C006253 pirinixic acid pirinixic acid results in decreased expression of WDR26 mRNAdecreases expression 11798191
C006253 pirinixic acid pirinixic acid affects the expression of WDR26 mRNAaffects expression 19483382
D011441 Propylthiouracil Propylthiouracil affects the expression of WDR26 mRNAaffects expression 19483382
D013853 Thioacetamide Thioacetamide affects the expression of WDR26 mRNAaffects expression 19483382
C025643 vinclozolin vinclozolin affects the expression of WDR26 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.2318653653
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.6316434500
MESH:D018246 Adrenocortical Adenoma Arsenic 5.3917306315
MESH:D000799 Angioedema Acetaminophen 4.0210982225
MESH:D001008 Anxiety Disorders vinclozolin 3.7319015723
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.9020041841 18218290 18057881
MESH:D020261 Arsenic Poisoning Arsenic 2.8916251483 12569548 18414634 16835338
MESH:D050197 Atherosclerosis Arsenic 3.3119371607 12928151
MESH:D001281 Atrial Fibrillation Amiodarone 3.9819698954 18651412
MESH:D001321 Autistic Disorder Acetaminophen 1.4118445737
MESH:D001778 Blood Coagulation Disorders Amiodarone 53.0919483382
MESH:D001778 Blood Coagulation Disorders Benzbromarone 53.0919483382
MESH:D001778 Blood Coagulation Disorders Clofibrate 53.0919483382
MESH:D001778 Blood Coagulation Disorders Ethionine 53.0919483382
MESH:D001778 Blood Coagulation Disorders Omeprazole 53.0919483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 53.0919483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 53.0919483382
MESH:D001778 Blood Coagulation Disorders Thioacetamide 53.0919483382
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.6517687452 15504454
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 6.783084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 6.7817306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Benzbromarone 6.781701930
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 6.7817997003
MESH:D002294 Carcinoma, Squamous Cell Arsenic 2.7215504454 17687452 18922899
MESH:D002295 Carcinoma, Transitional Cell Arsenic 4.1818640142
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.9219225199 15710769
MESH:D002318 Cardiovascular Diseases Arsenic 3.5215738583 19152805 17938729
MESH:D002340 Carotid Artery Diseases Arsenic 4.4116973168 18022660
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.2418974383
MESH:D002386 Cataract Acetaminophen 2.6410977129
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 3.591399818
MESH:D002637 Chest Pain Omeprazole 5.2815447763
MESH:D018281 Cholangiocarcinoma Thioacetamide 4.3918291259
MESH:D002779 Cholestasis pirinixic acid 2.9119176532
MESH:D003456 Cryptorchidism vinclozolin 4.4714966744
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4718249437
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.5014725611 19923254 12153990 19164858 16781746 10774834 19739265 14986274 11529661 19416960 10663392 11461765 14550746 12392966 18713872 11739529 12540782 16393943 19370779 19420014 19085960 16109766 16177239 10915739 17906064 15968718 17522070 11421492 12594235 15619225 11834606 17562736 16081117 2444490 11743745 12705907 18071297 12958197 16227642 11287661 16485898
MESH:D056486 Drug-Induced Liver Injury Amiodarone 6.5018218290 15265979
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 6.5012963478
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.2719426721
MESH:D004381 Duodenal Ulcer Omeprazole 4.4517151854 16613094 21218061 15991576
MESH:D050171 Dyslipidemias Clofibrate 4.1416707586
MESH:D004487 Edema pirinixic acid 2.5912083418
MESH:D005218 Fat Necrosis Thioacetamide 5.8916456712
MESH:D005234 Fatty Liver Amiodarone 13.8814986274
MESH:D005234 Fatty Liver Clofibrate 13.8819224547
MESH:D005234 Fatty Liver pirinixic acid 13.8820131406 19236843
MESH:D005534 Foot Diseases Arsenic 5.736392382
MESH:D005756 Gastritis Acetaminophen 3.8516983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.0916973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.4716417039
MESH:D006333 Heart Failure pirinixic acid 2.6020558911
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.6815929193 18665440 17276928
MESH:D006505 Hepatitis Thioacetamide 4.3416456712
MESH:D006529 Hepatomegaly Amiodarone 9.0415265979
MESH:D006529 Hepatomegaly pirinixic acid 9.0419772884 16221962 19176532 18467677
MESH:D006930 Hyperalgesia Acetaminophen 2.7916870215
MESH:D006937 Hypercholesterolemia Amiodarone 3.988137927 9751232
MESH:D006943 Hyperglycemia pirinixic acid 3.2920558911
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.5617050553
MESH:D006973 Hypertension Arsenic 2.909931084 16076760 11953799
MESH:D006987 Hypesthesia Arsenic 5.7316093927
MESH:D007037 Hypothyroidism Amiodarone 12.0818020914 17991464
MESH:D007037 Hypothyroidism Propylthiouracil 12.0818031379 8137927
MESH:D007248 Infertility, Male vinclozolin 3.1116467254
MESH:D007333 Insulin Resistance pirinixic acid 2.7016306350
MESH:D007642 Keratosis Arsenic 5.1412749816 16930632
MESH:D007674 Kidney Diseases Acetaminophen 2.2615629191 12587719
MESH:D016773 Leishmaniasis, Cutaneous Omeprazole 4.1919248655
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 3.6217339181
MESH:D007984 Leydig Cell Tumor vinclozolin 4.8916417039
MESH:D008064 Lipidoses Amiodarone 3.5915342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.5815474484
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 2.5816343077 18416461 18380797 17629604 17292413 15334695 16097051 14739098 18031379 12557150 16248980 18615449 18606216 17127702 15288472 12085344 17355460 11172339 18458672 16098781 10677585 15716488 18263696 15288473 15362042 16126171 11682029 12891558 15078482 15316131 11481614 15474484 15158331 18032466 17050028 15095483 12679928 12531686 12175628 15075984 15465738 16511523 16489207 18395095 18295389
MESH:D008107 Liver Diseases Acetaminophen 6.7712587719 19014921 16610002 12969438 11587558 19784758 19460945 16611625
MESH:D008107 Liver Diseases Arsenic 6.7711134558
MESH:D008107 Liver Diseases Thioacetamide 6.7716337175 15158337 18374380
MESH:D017114 Liver Failure, Acute Acetaminophen 9.9817185352 16871587
MESH:D017114 Liver Failure, Acute Thioacetamide 9.9817276928 15313186 12479984 15633222
MESH:D008113 Liver Neoplasms Arsenic 4.7316368122
MESH:D008113 Liver Neoplasms pirinixic acid 4.7315890375 20007298 16377806
MESH:D008133 Long QT Syndrome Amiodarone 3.6615350150 17391786 11989578
MESH:D008171 Lung Diseases Amiodarone 3.4412587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 4.6518516814
MESH:D008175 Lung Neoplasms Arsenic 2.2017976673 17306315 19168569
MESH:D008546 Melanoma, Experimental Acetaminophen 3.7119513568
MESH:D009135 Muscular Diseases pirinixic acid 3.6416239165
MESH:D009181 Mycoses Amiodarone 5.0812754197 17974566
MESH:D009203 Myocardial Infarction pirinixic acid 2.1819151258
MESH:D017202 Myocardial Ischemia Arsenic 4.0715371236
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.0316411023
MESH:D009369 Neoplasms pirinixic acid 1.9917405874
MESH:D009436 Neural Tube Defects Arsenic 3.5216620997
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.9618514411
MESH:D020078 Neurogenic Inflammation Arsenic 4.4917056641
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 5.089802331
MESH:D009765 Obesity pirinixic acid 1.8420558911
MESH:D010051 Ovarian Neoplasms Arsenic 2.7717306315
MESH:D010146 Pain Acetaminophen 2.4816870215
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.3016093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 5.1416905509 6392382 15371236
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 4.0518220299 19015723 18042343
MESH:D011469 Prostatic Diseases vinclozolin 5.0918220299
MESH:D011471 Prostatic Neoplasms Arsenic 3.5916140617
MESH:D011472 Prostatitis vinclozolin 5.0918629315
MESH:D011507 Proteinuria Arsenic 4.1221343184
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.8912490602 11597910 12832656
MESH:D015427 Reperfusion Injury pirinixic acid 2.4319058328
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.2418724381
MESH:D012871 Skin Diseases Arsenic 2.7715952646 6392382 18709164 16702368 17938729 16759981 17548696 19834688 17453740 16353154 17050553
MESH:D012878 Skin Neoplasms Arsenic 6.1017029826 17976673 16251483 15504454 19538983 17050553
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 6.108532709
MESH:D013272 Stomach Diseases Omeprazole 4.7618545984
MESH:D013276 Stomach Ulcer Amiodarone 7.9418087811
MESH:D013276 Stomach Ulcer Omeprazole 7.9418237397 17977527 10750652 15991576 16755016 11906479
MESH:D013610 Tachycardia Amiodarone 4.4211238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.3219225199
MESH:D013959 Thyroid Diseases Amiodarone 4.9319731979
MESH:D013964 Thyroid Neoplasms Propylthiouracil 3.7615710170
MESH:D013971 Thyrotoxicosis Amiodarone 5.0018020914 19584973
MESH:D016171 Torsades de Pointes Amiodarone 4.3417467628 11989578
MESH:D001749 Urinary Bladder Neoplasms Arsenic 2.8515987713 19322015 17976673 11144890 19429237 17306315 18640142
MESH:D014581 Urticaria Acetaminophen 3.0910982225
MESH:D014652 Vascular Diseases Arsenic 4.8917056641
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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