AutismKB 2.0

Annotation Detail for ADAM33


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ADAM33 ( C20orf153,DJ964F7.1,DKFZp434K0521,FLJ35308,FLJ36751,MGC149823,MGC71889 )
Gene Full Name: ADAM metallopeptidase domain 33
Band: 20p13
Quick LinksEntrez ID:80332; OMIM: 607114; Uniprot ID:ADA33_HUMAN; ENSEMBL ID: ENSG00000149451; HGNC ID: 15478
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Desease IDDesease Name
H00079Asthma
Immune system diseases
Allergies and autoimmune diseases
Desease IDDesease Name
1708Bronchial hyperreactivity
2074Asthma
Desease Name
asthma, aspirin-intolerant
lung function
Asthma
allergic rhinitis
IMMUNE
BHR
respiratory syncytial virus bronchiolitis
INFECTION
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of ADAM33 mRNAdecreases expression 17557909
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 5.3617505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.9014692618
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.3711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.9615885639
MESH:D002779 Cholestasis Ethinyl Estradiol 3.2816105132 17681005 16919318 17110522 11677210 17333356 15861022
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.9712538720
MESH:D005234 Fatty Liver Ethinyl Estradiol 3.4415345470
MESH:D007021 Hypospadias Ethinyl Estradiol 4.7216945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 4.1612013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.8217937319
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.3811578682
MESH:D011537 Pruritus Ethinyl Estradiol 4.4016919318 15861022
MESH:D013088 Spermatocele Ethinyl Estradiol 5.3616709447
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.3211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.6815669648
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 4.0814692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 4.1715869587 14671159
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA24526
  • No data
    Releated disease ID Related disease Name
    PA447178Pulmonary Disease, Chronic Obstructive
    PA443450Asthma
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB02944 - Alpha-D-Mannose
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018