AutismKB 2.0

Annotation Detail for CUL5


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Basic Information Top
Gene Symbol:CUL5 ( VACM-1,VACM1 )
Gene Full Name: cullin 5
Band: 11q22.3
Quick LinksEntrez ID:8065; OMIM: 601741; Uniprot ID:CUL5_HUMAN; ENSEMBL ID: ENSG00000166266; HGNC ID: 2556
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04120Ubiquitin mediated proteolysis
Pathway IDPathway Name
HIV Infection
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of CUL5 mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CUL5 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of CUL5 mRNAincreases expression 17530438
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CUL5 mRNAaffects cotreatment|decreases expression 18164116
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of CUL5 mRNAincreases expression 20064835
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CUL5 mRNAdecreases expression 19150397
C006780 bisphenol A bisphenol A results in decreased expression of CUL5 mRNAdecreases expression 20678512
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CUL5 mRNAaffects cotreatment|decreases expression 18164116
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of CUL5 mRNAaffects expression 17555576
D005472 Fluorouracil Fluorouracil results in increased expression of CUL5 mRNAincreases expression 16557594
D013629 Tamoxifen Tamoxifen affects the expression of CUL5 mRNAaffects expression 17555576
C004648 testosterone enanthate testosterone enanthate affects the expression of CUL5 mRNAaffects expression 17440010
D014212 Tretinoin Tretinoin results in decreased expression of CUL5 mRNAdecreases expression 17045167
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.6814745880
MESH:D000138 Acidosis Ammonium Chloride 3.6818287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0817505938
MESH:D000230 Adenocarcinoma arsenic trioxide 10.3319825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 10.3320464547 20127859
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 10.3314692618
MESH:D000230 Adenocarcinoma Fluorouracil 10.3317638652
MESH:D000236 Adenoma Benzo(a)pyrene 11.476695378
MESH:D000236 Adenoma beta-Naphthoflavone 11.4719389873
MESH:D000236 Adenoma Diethylnitrosamine 11.4710737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 4.0219061943 19052882 17620307 16434500 17162532 18056438
MESH:D000505 Alopecia Tretinoin 3.6815955085
MESH:D000740 Anemia Fluorouracil 3.7916511603 17963324 15504547
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.1819183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.3715885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.3716412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2816292516
MESH:D001249 Asthma Tretinoin 2.3616456186
MESH:D001471 Barrett Esophagus Tretinoin 4.5016935849
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 9.4416206674
MESH:D001778 Blood Coagulation Disorders Tretinoin 9.4416197459 16206674
MESH:D001862 Bone Resorption bisphenol A 3.9411985600
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.9917474063 20146248
MESH:D001943 Breast Neoplasms bisphenol A 2.9917123778
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.9917474063
MESH:D001943 Breast Neoplasms Fluorouracil 2.9915136595 16557594 19217205 16595493 18357371 16110121 18608205
MESH:D001943 Breast Neoplasms Tamoxifen 2.9916273361 19115204 20065188 20135344 17261762 18425577 19288272 20544844 18821012 18351453 18997820 19142967 18984771 19289846 16818667 18855134 19244106 18629630 19103187 15565566 17440819 11161223 19066611 16202921 20005174 19155303 19487384 15668708 17049068 18815881 20390343 19189212 21138602 16873071 17242785 19200415 19410462 19221464 19059307 21152245 19189210 19084267 19011961 17893378 20859285
MESH:D001943 Breast Neoplasms Tretinoin 2.9916873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.7116813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.4211589617
MESH:D002276 Carcinoid Tumor Fluorouracil 4.8016051944
MESH:D002277 Carcinoma Fluorouracil 3.6317121937
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.6119066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.2916168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 11.5616705839
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 11.5616217749 14691202 15073043 11135700 15553829
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 11.5620727157 20432363 16328049 18785209 17055752 3084413 19539802 18056438 17978847 16698587 19171122 19052882 17138121 19822196 16878318 19335982 16502159 21159647 20514400 20935162 16288022 19519916 17173139 3581430 10672840 18691550 18788625 16681979 19701751 16807293 18506893 19394651 18393292 16779866 17761372 17428255 18978308 19107877 16540662 10737359 16830150 18210153 16935385 18494052 16569478 20084675 20214788 20101231 19208518 17162532 19919837 20512989 18971187 19383236 19418558 20524982 18665156 20007298 11831363
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 11.5618930000 17088986 16799960 16332177 17971768 17045692
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.5616924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 11.561917145
MESH:D002278 Carcinoma in Situ bisphenol A 5.1117123778
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.0119014326
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 3.0518695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.1912490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 7.6620419170
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 7.6616757204 18986760 16280240 17066447
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 7.6616096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.6917572228
MESH:D002386 Cataract Tretinoin 3.1417460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.8620889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 6.867505956 21159647 2727394 17174075
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.7116129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.7619052882
MESH:D002779 Cholestasis Ethinyl Estradiol 2.9311677210 17110522 15861022 17333356 16105132 17681005 16919318
MESH:D002822 Choriocarcinoma Tretinoin 5.2916461808
MESH:D002972 Cleft Palate Tretinoin 2.709407595
MESH:D003092 Colitis Tretinoin 3.8117035595
MESH:D003110 Colonic Neoplasms Fluorouracil 2.2417169374 17725105 17018589 16510598 17016597 15001691 18772588 17287894 17172411 16340194
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.5620501625
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.5616331619 18288408 16303861 17016601 17401013 17594712 17454858 14970324 18509181 17255274 20501625 17094418 18802399 18949393 15148649 15289873 16524972 18383874 16282729 17695437 16391804 18448328
MESH:D023903 Coronary Restenosis arsenic trioxide 4.2812609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.7010525206
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.709125849 16925845 9664655 17551590 9224671 10589399 9142499 8800419 9211117 14991402
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.1218551238
MESH:D007644 Darier Disease Fluorouracil 4.9116733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.1815213294
MESH:D003711 Demyelinating Diseases Tamoxifen 4.4719031437
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.2120387270
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.5519279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 3.9618551238 21346803
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 3.9619107877
MESH:D004489 Edema, Cardiac Tretinoin 4.6018230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.2612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 9.2619031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.6119155303 17893378 20544844 16202921
MESH:D016889 Endometrial Neoplasms Tretinoin 7.6116569247
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.2516302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.5620426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 10.5612903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 10.5616530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 10.5616785472 17638652 15173087 16481741 16337965
MESH:D005124 Eye Abnormalities Tretinoin 3.6416938888 9664655
MESH:D005234 Fatty Liver arsenic trioxide 19.4815073043
MESH:D005234 Fatty Liver Diethylnitrosamine 19.4821071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 19.4815345470
MESH:D005234 Fatty Liver Tamoxifen 19.4814986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2816709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.6414745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.3019069698
MESH:D005355 Fibrosis Tretinoin 3.6217994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.3616904648
MESH:D005909 Glioblastoma Tretinoin 3.0517312396
MESH:D005910 Glioma Fluorouracil 2.9016145905
MESH:D006258 Head and Neck Neoplasms Fluorouracil 7.9715102660 15162350 18337622
MESH:D006258 Head and Neck Neoplasms Tretinoin 7.9716096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.2916084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.7920471113
MESH:D006330 Heart Defects, Congenital Tretinoin 6.7914991402 9664655
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.8817440010
MESH:D006930 Hyperalgesia Tretinoin 3.2816870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.6716778211
MESH:D007021 Hypospadias Ethinyl Estradiol 3.9116945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.5512013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5417937319
MESH:D007249 Inflammation Diethylnitrosamine 5.2118785209
MESH:D007249 Inflammation Tamoxifen 5.2119457130
MESH:D007333 Insulin Resistance bisphenol A 3.3416393666
MESH:D007410 Intestinal Diseases Tretinoin 3.8717994277
MESH:D007569 Jaw Abnormalities Tretinoin 3.9817551590 15992940
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 12.8616705839
MESH:D007680 Kidney Neoplasms Fluorouracil 12.8616985049
MESH:D007680 Kidney Neoplasms Tamoxifen 12.8618625569
MESH:D007938 Leukemia arsenic trioxide 6.4715070760
MESH:D007938 Leukemia Tretinoin 6.4717143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.8812560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.4216972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.4914633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.7519077051
MESH:D007951 Leukemia, Myeloid Tretinoin 9.7516482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.9320471514 16467208 16968895 17050201 19850784
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.9319850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.8115336539 17649720 19225113 15622746 17217047 15213294 17869043 16891316 11161223 16823087 16966277 16331271 12018890 17712046 12679006 15748426 16112521 19642359 19035177 16330433 19075265 17107899 9834237 11468182 12712474
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.8119225113 17217047 16766008 17107899 15748426 9834237 17301526 17339181 16331271 17712046 19029980 17294898 16935935 16891316 12679006 16140955 17368321 16823087 17506722 17361223 16788101 17649720 19075265 19642359 19035177
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.4516882451
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.369224671
MESH:D008064 Lipidoses Tamoxifen 3.2115342952 17567588
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.8719638242 18522880 18407596 18665156 20032147
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 2.5118564211
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 2.5118397230 16248980
MESH:D008107 Liver Diseases Diethylnitrosamine 2.1217034775
MESH:D008113 Liver Neoplasms arsenic trioxide 18.3814682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 18.3821137059 20195826
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 18.3821295105 19389873
MESH:D008113 Liver Neoplasms Diethylnitrosamine 18.3819833225 21167192 2422723 19254457 18978307 2862719 20405173 19642983 19256749 18648771 19090486 15175105 19427195 21071580 9163691 20583210 20492335 20101389 20501860 18977376 15885732 19255062 19551842 19996281 18754104 12112319 18644402 19690152 19812893 12771043 20434301 20137499 16942905 19294768 20118626 19638242 10737359 20452335 19073162 19499222 19850985 21278145 21047994 19426721
MESH:D008113 Liver Neoplasms Fluorouracil 18.3816603448 17045692 18383874 15113037
MESH:D008113 Liver Neoplasms Tamoxifen 18.3816684651
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 10.2420377131
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 10.2418164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 10.2418079962 19126423 19539802 18775883 16267830 18164116 19009564 18544905 16842330 17174075 19519916 3124819 9362446 18282651 18308698 19004024 21159647 17942915 2563599 18253720 18093689 17854601
MESH:D008133 Long QT Syndrome arsenic trioxide 3.4115213294
MESH:D008175 Lung Neoplasms arsenic trioxide 6.6911798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 6.6920869020 18569708 20064080 20464547 20135361 18816296 6695378 18520028 17053015
MESH:D008175 Lung Neoplasms Diethylnitrosamine 6.6920970405 20512841 6695378 21163286
MESH:D008175 Lung Neoplasms Fluorouracil 6.6915246190
MESH:D008175 Lung Neoplasms Tamoxifen 6.6918625569
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.9115086387
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.8819428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.6716827153 19196722 19196723 11731420 14580682
MESH:D020149 Manganese Poisoning Tamoxifen 4.6819453300
MESH:D008527 Medulloblastoma Tretinoin 2.8117453147
MESH:D008545 Melanoma Tamoxifen 3.3319393235 12393984
MESH:D008545 Melanoma Tretinoin 3.3316752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.3015990972
MESH:D008591 Meningomyelocele Tretinoin 4.5316940565
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 8.7416381670
MESH:D009062 Mouth Neoplasms Fluorouracil 8.7416757204 18986760
MESH:D009101 Multiple Myeloma arsenic trioxide 3.1614977855 15949261 19417148 11468182 19549372
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.8118349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.5416882451 16105982
MESH:D009190 Myelodysplastic Syndromes Tretinoin 7.5417596541
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.9718551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.0516624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.833581430 9029167
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.8319393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5419410462
MESH:D009369 Neoplasms Benzo(a)pyrene 8.5011141357
MESH:D009369 Neoplasms Fluorouracil 8.5018239605 16928823 18600527
MESH:D009369 Neoplasms Tretinoin 8.5016946489 16594593
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.1319200415 19189210 19196722
MESH:D009421 Nervous System Malformations bisphenol A 10.1111399458 16427766
MESH:D009421 Nervous System Malformations Tretinoin 10.119125849
MESH:D009436 Neural Tube Defects arsenic trioxide 7.4710525206
MESH:D009436 Neural Tube Defects Tretinoin 7.479142499
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.4120387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.2520387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.4916436463
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.5016049721 12819281
MESH:D010049 Ovarian Diseases bisphenol A 5.1111985600
MESH:D010051 Ovarian Neoplasms arsenic trioxide 4.9516624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Tretinoin 4.9516936753
MESH:D010146 Pain Tretinoin 2.9716870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 12.5715580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 12.5716540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 12.5715113037 16929163 16500647 19003803
MESH:D010190 Pancreatic Neoplasms Tretinoin 12.5715976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7711578682
MESH:D010235 Paraganglioma arsenic trioxide 4.2519927285
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.622563599
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 4.0710548101
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.2920887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.8619131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.8617292933
MESH:D011471 Prostatic Neoplasms bisphenol A 1.8616740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 1.8618626508 19082440
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.8615067354
MESH:D011507 Proteinuria Tretinoin 3.6916636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.4315861022 16919318
MESH:D011625 Pterygium Tretinoin 4.9116723453
MESH:D011629 Puberty, Precocious bisphenol A 4.9010548101
MESH:D012004 Rectal Neoplasms Fluorouracil 4.0818722050 15538739 18286688 16160472
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.1916283617 16116481
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.0516646077
MESH:D012640 Seizures 2,4-dinitrotoluene 2.5818551238
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.8019755658 10029692
MESH:D012878 Skin Neoplasms Tretinoin 5.8016467112
MESH:D013088 Spermatocele Ethinyl Estradiol 12.0116709447
MESH:D013088 Spermatocele Tamoxifen 12.0116709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.1519457130
MESH:D013274 Stomach Neoplasms arsenic trioxide 6.4817007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 6.4820155912 2093021
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 6.4818456281
MESH:D013274 Stomach Neoplasms Fluorouracil 6.4817522103 18567086 16424979 17172411 16951190 17498489 18396642 15786421 19015929 19084572
MESH:D013274 Stomach Neoplasms Tretinoin 6.4817261132
MESH:D019966 Substance-Related Disorders bisphenol A 4.1016045194 16684133
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.7111994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2215669648
MESH:D013964 Thyroid Neoplasms arsenic trioxide 12.3519014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 12.357505956
MESH:D013964 Thyroid Neoplasms Tretinoin 12.3517045167 16026305
MESH:D014062 Tongue Neoplasms Fluorouracil 10.0916280240
MESH:D014062 Tongue Neoplasms Tretinoin 10.0916051514
MESH:D016171 Torsades de Pointes arsenic trioxide 4.0815213294
MESH:D014376 Tuberculosis Tretinoin 3.2716040207
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 12.1716049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 12.1711780464 20435036 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 12.1717053015
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 12.1716712894 8653321 17572228
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.4310091137
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 9.7116803524
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 9.7116129372
MESH:D014591 Uterine Diseases bisphenol A 5.1414652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3914692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.7416752155
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.6214671159 15869587
MESH:D014820 Vitiligo Tretinoin 4.1516761959
MESH:D009396 Wilms Tumor Tretinoin 4.0416287080
Pathway ID Pathway Name
REACT:6185 HIV Infection
KEGG:04120 Ubiquitin mediated proteolysis
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018