AutismKB 2.0

Annotation Detail for NDFIP1


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Basic Information Top
Gene Symbol:NDFIP1 ( MGC10924,N4WBP5 )
Gene Full Name: Nedd4 family interacting protein 1
Band: 5q31.3
Quick LinksEntrez ID:80762; OMIM: 612050; Uniprot ID:NFIP1_HUMAN; ENSEMBL ID: ENSG00000131507; HGNC ID: 17592
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of NDFIP1 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of NDFIP1 mRNAaffects expression 17562736
D014501 Uranium Uranium affects the expression of NDFIP1 mRNAaffects expression 15672453
C005460 uranyl acetate uranyl acetate affects the expression of NDFIP1 mRNAaffects expression 15672453
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 2.9616705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.963084413
MESH:D002386 Cataract Acetaminophen 2.7910977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.036135515
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.5818551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 4.0218551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.0215619225 12705907 19923254 17906064 12392966 15968718 17562736 12958197 11834606 19739265 14550746 14725611 16109766 11287661 12594235 10663392 16177239 17522070 19370779 11421492 11743745 11529661 19085960 10915739 2444490 11461765 16227642 18071297 16081117 19416960 12540782 16781746 19420014 14986274 19164858 18713872 16393943 12153990 10774834 11739529 16485898
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4015629191 12587719
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.3216705839
MESH:D008107 Liver Diseases Acetaminophen 1.7019014921 12969438 19460945 16610002 19784758 16611625 12587719 11587558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6316871587 17185352
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.277678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.772876784 6135515 2876786
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.497678174 18551238
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2118514411
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.8316049721
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D012640 Seizures 2,6-dinitrotoluene 2.7918551238
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.4116049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.9510091137
MESH:D014581 Urticaria Acetaminophen 3.4410982225
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018