Annotation Detail for MLL2
Basic Information
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| Gene Symbol: | MLL2 ( AAD10,ALR,CAGL114,KMT2B,KMT2D,MLL4,TNRC21 ) |
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| Gene Full Name: | myeloid/lymphoid or mixed-lineage leukemia 2 |
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| Band: | 12q12-q14 |
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| Quick Links | Entrez ID:8085; OMIM: 602113; Uniprot ID:MLL2_HUMAN; ENSEMBL ID: ENSG00000167548; HGNC ID: |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
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| D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of MLL2 mRNA | decreases expression | 20018196
19150397
|
| D015735 |
Mifepristone |
Mifepristone results in decreased expression of MLL2 mRNA | decreases expression | 17584828
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
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| MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
3.04 | 20889678 |
| MESH:D004715 |
Endometriosis |
|
Mifepristone |
4.87 | 16134523 |
| MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.16 | 20426865 |
| MESH:D007248 |
Infertility, Male |
marker/mechanism |
|
| 19348672 |
| MESH:C537705 |
Kabuki syndrome |
marker/mechanism |
|
| 20711175 |
| MESH:D010051 |
Ovarian Neoplasms |
|
Mifepristone |
3.24 | 16525653 |
| Pathway ID |
Pathway Name |
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| KEGG:00310 |
Lysine degradation |
Related Pathway Information