Annotation Detail for AP3B2
Basic Information Top
| Gene Symbol: | AP3B2 ( DKFZp686D17136,NAPTB ) |
|---|---|
| Gene Full Name: | adaptor-related protein complex 3, beta 2 subunit |
| Band: | 15q25.2 |
| Quick Links | Entrez ID:8120; OMIM: 602166; Uniprot ID:AP3B2_HUMAN; ENSEMBL ID: ENSG00000103723; HGNC ID: 567 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Diseases/Disorders| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of AP3B2 mRNA | affects expression | 17562736 |
| D008345 | Manganese | Manganese results in increased expression of AP3B2 mRNA | increases expression | 17175027 |
| C025340 | manganese chloride | manganese chloride results in increased expression of AP3B2 mRNA | increases expression | 17175027 |
| D010100 | Oxygen | Oxygen deficiency results in increased expression of AP3B2 mRNA | increases expression | 17175027 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D055371 | Acute Lung Injury | Oxygen | 4.99 | 16759491 | |
| MESH:D000756 | Anemia, Sideroblastic | Manganese | 12.48 | 16910769 | |
| MESH:D000756 | Anemia, Sideroblastic | manganese chloride | 12.48 | 16910769 | |
| MESH:D000799 | Angioedema | Acetaminophen | 4.57 | 10982225 | |
| MESH:D000860 | Anoxia | Oxygen | 5.69 | 20872349 | |
| MESH:D050197 | Atherosclerosis | Oxygen | 4.01 | 16391483 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.40 | 18445737 | |
| MESH:D001943 | Breast Neoplasms | Oxygen | 3.18 | 17263869 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.79 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.67 | 12392966 16485898 10774834 12594235 11421492 11739529 17522070 16393943 19085960 11743745 15619225 18713872 16177239 19420014 12958197 19370779 16081117 19923254 16109766 2444490 15968718 17562736 18071297 19164858 19739265 10663392 14986274 11287661 17906064 14725611 11529661 16227642 14550746 12153990 19416960 10915739 12705907 11461765 12540782 11834606 16781746 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.82 | 19426721 | |
| MESH:D004417 | Dyspnea | Oxygen | 5.55 | 20016425 | |
| MESH:D005739 | Gas Poisoning | Oxygen | 5.94 | 20016425 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.40 | 16983495 | |
| MESH:D005909 | Glioblastoma | Manganese | 4.15 | 17043766 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.02 | 16870215 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.40 | 15629191 12587719 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.70 | 19784758 11587558 12969438 16610002 19460945 12587719 19014921 16611625 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.63 | 17185352 16871587 | |
| MESH:D055370 | Lung Injury | Oxygen | 5.07 | 18339021 | |
| MESH:D020149 | Manganese Poisoning | Manganese | 6.24 | 16568477 19453300 16551646 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.13 | 19513568 | |
| MESH:D009069 | Movement Disorders | Manganese | 5.47 | 16551646 | |
| MESH:D009410 | Nerve Degeneration | Manganese | 4.58 | 16551646 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.21 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.73 | 16870215 | |
| MESH:D010300 | Parkinson Disease | Manganese | 3.49 | 11181820 | |
| MESH:D020734 | Parkinsonian Disorders | Manganese | 4.86 | 16140633 | |
| MESH:D012128 | Respiratory Distress Syndrome, Adult | Oxygen | 4.97 | 18339021 17627322 | |
| MESH:D013398 | Sudden Infant Death | Oxygen | 6.18 | 12563064 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.44 | 10982225 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:04142 | Lysosome |