AutismKB 2.0

Annotation Detail for SLC7A5


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SLC7A5 ( 4F2LC,CD98,D16S469E,E16,LAT1,MPE16,hLAT1 )
Gene Full Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
Band: 16q24.2
Quick LinksEntrez ID:8140; OMIM: 600182; Uniprot ID:LAT1_HUMAN; ENSEMBL ID: ENSG00000103257; HGNC ID: 11063
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Transmembrane transport of small molecules
Amino acid and oligopeptide SLC transporters
Hemostasis
Metabolism of amino acids and derivatives
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of SLC7A5 mRNAaffects expression 21346803
C016601 4-hydroxytamoxifen 4-hydroxytamoxifen results in increased expression of SLC7A5 mRNAincreases expression 19901195
D000082 Acetaminophen Acetaminophen affects the expression of SLC7A5 mRNAaffects expression 17562736
C103505 AM 251 AM 251 results in increased expression of SLC7A5 mRNAincreases expression 16500647
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SLC7A5 mRNAaffects expression 16483693
D019324 beta-Naphthoflavone beta-Naphthoflavone results in increased expression of SLC7A5 mRNAincreases expression 19737606
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of SLC7A5 mRNAincreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SLC7A5 mRNAdecreases expression 19150397
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of SLC7A5 mRNAincreases expression 17944540
C095105 bexarotene bexarotene results in decreased expression of SLC7A5 mRNAdecreases expression 17178900
C006780 bisphenol A bisphenol A affects the expression of SLC7A5 mRNAaffects expression 20170705
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of SLC7A5 mRNAdecreases expression 12419474
D003513 Cycloheximide [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SLC7A5 mRNAaffects cotreatment|increases expression 19684285
D016572 Cyclosporine Cyclosporine results in increased expression of SLC7A5 mRNAincreases expression 20106945
C004742 daidzein daidzein results in increased expression of SLC7A5 mRNAincreases expression 15757668
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of SLC7A5 mRNAincreases expression 19371625
D004958 Estradiol Estradiol results in decreased expression of SLC7A5 mRNAdecreases expression 20106945
D004958 Estradiol Estradiol results in increased expression of SLC7A5 mRNAincreases expression 17555868
15757668
D004958 Estradiol Estradiol results in increased expression of SLC7A5 mRNAincreases expression 14664709
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of SLC7A5 mRNAaffects expression 20170705
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of SLC7A5 mRNAaffects expression 20170705
D005047 Etoposide SLC7A5 protein affects the susceptibility to Etoposideaffects response to substance 16217747
D015025 Zearalenone Zearalenone results in increased expression of SLC7A5 mRNAincreases expression 19371625
D005419 Flavonoids Flavonoids results in decreased expression of SLC7A5 mRNAdecreases expression 18035473
D019833 Genistein Genistein results in increased expression of SLC7A5 mRNAincreases expression 15757668
D017313 Fenretinide Fenretinide results in increased expression of SLC7A5 mRNAincreases expression 15958647
D006861 Hydrogen Peroxide Hydrogen Peroxide results in decreased expression of SLC7A5 mRNAdecreases expression 12419474
D007213 Indomethacin Indomethacin results in increased expression of SLC7A5 mRNAincreases expression 16184411
D008942 Mitoxantrone SLC7A5 protein affects the susceptibility to Mitoxantroneaffects response to substance 16217747
C029938 nickel sulfate nickel sulfate results in increased expression of SLC7A5 mRNAincreases expression 16780908
C030110 oxaliplatin oxaliplatin results in decreased expression of SLC7A5 mRNAdecreases expression 17762391
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of SLC7A5 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of SLC7A5 mRNAincreases expression 19482888
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of SLC7A5 mRNAaffects binding|increases activity|increases expression 19710929
D011374 Progesterone Progesterone results in decreased expression of SLC7A5 mRNAdecreases expression 18037150
C064116 S-(1,1,2,2-tetrafluoroethyl)cysteine S-(1,1,2,2-tetrafluoroethyl)cysteine results in increased expression of SLC7A5 mRNAincreases expression 16678137
D012643 Selenium Selenium results in increased expression of SLC7A5 mRNAincreases expression 19244175
C017947 sodium arsenite sodium arsenite results in increased expression of SLC7A5 mRNAincreases expression 12760830
D013629 Tamoxifen Tamoxifen results in decreased expression of SLC7A5 mRNAdecreases expression 19155303
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SLC7A5 mRNAaffects cotreatment|increases expression 19684285
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SLC7A5 mRNAincreases expression 19684285
20106945
17555868
11489354
19901195
16697128
D014212 Tretinoin Tretinoin results in decreased expression of SLC7A5 mRNAdecreases expression 16054129
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.1714745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 7.086195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.0811752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.1918287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5717505938
MESH:D055371 Acute Lung Injury nickel sulfate 8.0216100012 12718980 19131640 11954676
MESH:D055371 Acute Lung Injury pirinixic acid 8.0218653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 19.2820127859 20464547
MESH:D000230 Adenocarcinoma daidzein 19.2811473722
MESH:D000230 Adenocarcinoma Estradiol 19.2811473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 19.2814692618
MESH:D000230 Adenocarcinoma Fenretinide 19.2810697514
MESH:D000230 Adenocarcinoma Genistein 19.2811473722
MESH:D000230 Adenocarcinoma Indomethacin 19.2816537180
MESH:D000236 Adenoma Benzo(a)pyrene 10.036695378
MESH:D000236 Adenoma beta-Naphthoflavone 10.0319389873
MESH:D000236 Adenoma Indomethacin 10.0311497255
MESH:D018248 Adenoma, Liver Cell Phenobarbital 15.1517620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 15.1516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 15.1516835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.3215276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.5317306315 16712894
MESH:D000505 Alopecia Tretinoin 3.3315955085
MESH:D016301 Alveolar Bone Loss Indomethacin 5.0017225004
MESH:D000544 Alzheimer Disease Indomethacin 2.6217627676 15579461
MESH:D000686 Amyloidosis Diethylstilbestrol 4.1315469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.6311748828
MESH:D000799 Angioedema Acetaminophen 3.4710982225
MESH:D001014 Aortic Aneurysm Indomethacin 4.5010231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 10.5119183758
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 10.5110388637
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.1111256880
MESH:D018771 Arthralgia Indomethacin 4.792160914
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.4415885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.4416412693
MESH:D001172 Arthritis, Rheumatoid Indomethacin 4.4411248219
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.4416292516
MESH:D001249 Asthma Tretinoin 2.2316456186
MESH:D001321 Autistic Disorder Acetaminophen 1.4618445737
MESH:D001471 Barrett Esophagus Tretinoin 4.0516935849
MESH:D001477 Bartter Syndrome Indomethacin 4.6210684365
MESH:D001778 Blood Coagulation Disorders pirinixic acid 13.3719483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.3712125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 13.3716206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5315746008
MESH:D019046 Bone Marrow Neoplasms Etoposide 4.7914601052
MESH:D001862 Bone Resorption bisphenol A 3.5411985600
MESH:D001929 Brain Edema Indomethacin 4.6511481608
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.9617868700
MESH:D001930 Brain Injuries Progesterone 3.9015845082 15665606 15380490
MESH:D002545 Brain Ischemia Indomethacin 4.0512524144
MESH:D001932 Brain Neoplasms Fenretinide 4.0416187019
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 10.5520146248 17474063
MESH:D001943 Breast Neoplasms bexarotene 10.5516818667 16344269
MESH:D001943 Breast Neoplasms bisphenol A 10.5517123778
MESH:D001943 Breast Neoplasms Diethylstilbestrol 10.5515324884 17129689
MESH:D001943 Breast Neoplasms Estradiol 10.5517261762 12948864 18497071 17018787 16675129 17289903 19861407 14630087
MESH:D001943 Breast Neoplasms Etoposide 10.5516322251
MESH:D001943 Breast Neoplasms Fenretinide 10.5516601279
MESH:D001943 Breast Neoplasms Genistein 10.5516541309 16873071 17200150
MESH:D001943 Breast Neoplasms Indomethacin 10.5517401462
MESH:D001943 Breast Neoplasms Progesterone 10.5515562024 17614352 16175315
MESH:D001943 Breast Neoplasms Tamoxifen 10.5517893378 18425577 19487384 11161223 18629630 19142967 15565566 20065188 19155303 16273361 17049068 21138602 19189210 19103187 19011961 20859285 20390343 19200415 19410462 18984771 15668708 21152245 19189212 20135344 18815881 20005174 19288272 17242785 19115204 16873071 19221464 19289846 20544844 19066611 19084267 17440819 17261762 18351453 16202921 19244106 16818667 18855134 19059307 18997820 18821012
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 10.5520435547
MESH:D001943 Breast Neoplasms Tretinoin 10.5516166294 16443354 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.2216813970
MESH:D002056 Burns Indomethacin 4.3510459503
MESH:D002100 Cachexia Indomethacin 4.6415141370 16537180 11239499 15625704
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0916111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.5116835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.1519066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.7816168501
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 24.5316705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 24.533084413
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 24.5316924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Estradiol 24.5316924424
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 24.5317159502 16270382
MESH:D006528 Carcinoma, Hepatocellular Genistein 24.5316924424
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 24.5316391822
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 24.531701930 20935162 6705139 17173139 20007298
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 24.5317306315 16507464 15276417
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 24.5316924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 24.531917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.6217123778
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 4.3611053908
MESH:D018276 Carcinoma, Medullary Indomethacin 4.9814736730 18791128 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.1016247446
MESH:D002292 Carcinoma, Renal Cell Indomethacin 3.2017341418
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 13.0920419170
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 13.0916274795
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 13.0912636206 15482327
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 13.0918572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 13.0916051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.3017572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.1618850075 16120746 18670907
MESH:D002318 Cardiovascular Diseases daidzein 10.8916332659
MESH:D002318 Cardiovascular Diseases Genistein 10.8916332659
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 10.8916936243
MESH:D002386 Cataract Acetaminophen 6.5010977129
MESH:D002386 Cataract Tretinoin 6.5017460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 18.396135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 18.3920889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 18.3912371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 18.3918566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 18.3920056578 19524636
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.894080065
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 11.7516154183
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 11.7516129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.8516835633
MESH:D002764 Cholecystitis Indomethacin 4.7911181007
MESH:D002779 Cholestasis Cyclosporine 11.7719486331
MESH:D002779 Cholestasis Ethinyl Estradiol 11.7711677210 17110522 16919318 17333356 17681005 15861022 16105132
MESH:D002779 Cholestasis pirinixic acid 11.7719176532
MESH:D002822 Choriocarcinoma Tretinoin 4.7816461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.2312621046 8697196 16354765 15668235 15340226
MESH:D002972 Cleft Palate Tretinoin 5.239407595
MESH:D003092 Colitis Selenium 8.3017936198
MESH:D003092 Colitis Tretinoin 8.3017035595
MESH:D003110 Colonic Neoplasms Genistein 5.5817182828
MESH:D003110 Colonic Neoplasms Indomethacin 5.5815963497 15936596 15637740 11260862 15625704 15786552
MESH:D003110 Colonic Neoplasms oxaliplatin 5.5816004971 16510598 16024531
MESH:D015179 Colorectal Neoplasms Fenretinide 3.5317273769
MESH:D015179 Colorectal Neoplasms Indomethacin 3.5317054584 12606626 18059344 11197048
MESH:D015179 Colorectal Neoplasms oxaliplatin 3.5317401013 17594712 17255274 17695437 18509181 18448328
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7514669216 17141729
MESH:D018352 Coronavirus Infections Indomethacin 5.3417302372
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.3220055451 15322242 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.3217551590 9664655 9142499 9125849 16925845 14991402 9224671 8800419 9211117 10589399
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.2116002989 12952375
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.6618551238
MESH:D003711 Demyelinating Diseases Tamoxifen 4.0019031437
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 3.3311298694 16780908 16823706
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2518249437
MESH:D003924 Diabetes Mellitus, Type 2 daidzein 6.6816647724
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 6.6816647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.6817107852
MESH:D003928 Diabetic Nephropathies Estradiol 7.8219279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 7.8219279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.1317187935
MESH:D003967 Diarrhea Indomethacin 3.457237001 7907874
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 7.9521346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 7.9512153990 14986274 18713872 11739529 19164858 12540782 12958197 10915739 17562736 14550746 16109766 12705907 10663392 14725611 15619225 18071297 15968718 16781746 19923254 19416960 16485898 19739265 16081117 11287661 11421492 11743745 16393943 16227642 17522070 11529661 19370779 17906064 16177239 11834606 19420014 11461765 2444490 19085960 10774834 12594235 12392966
MESH:D056486 Drug-Induced Liver Injury Selenium 7.9515131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 7.9520420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.7219426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.4911462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.7817190690 16326151 18043480 16133044 18446180 12774134
MESH:D004381 Duodenal Ulcer Indomethacin 3.7910671773 11535926 17329845 17045617 11595415 17151854 16699067 17202747 11991626 11595431 17351913
MESH:D004421 Dystonia Phenobarbital 3.671851702
MESH:D004487 Edema Indomethacin 9.578985016 19703484 8273558 10653021 16100529 7990266 7907874
MESH:D004487 Edema pirinixic acid 9.5712083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 9.5711000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.6918230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 10.6918230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 13.3012538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 13.3017692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 13.3019031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 10.6716402032
MESH:D004714 Endometrial Hyperplasia Genistein 10.6716402032
MESH:D016889 Endometrial Neoplasms 4-hydroxytamoxifen 31.3519148513
MESH:D016889 Endometrial Neoplasms daidzein 31.3511473722
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 31.3516804899 15700306
MESH:D016889 Endometrial Neoplasms Estradiol 31.3519148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Genistein 31.3511473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 31.3520544844 17893378 19155303 16202921
MESH:D016889 Endometrial Neoplasms Tretinoin 31.3516569247
MESH:D004715 Endometriosis Indomethacin 13.4615652904
MESH:D004715 Endometriosis Progesterone 13.4616134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 13.4610568697 9294722
MESH:D019446 Endotoxemia Indomethacin 4.1318509659
MESH:D004751 Enteritis Indomethacin 4.3710567023 17763956 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.6217980183
MESH:D004802 Eosinophilia Indomethacin 3.7011298111
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.753659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.503922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.7020417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.246401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.897750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.653659116
MESH:D007172 Erectile Dysfunction daidzein 4.6714972507
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.6620426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 6.6616530937
MESH:D004938 Esophageal Neoplasms Indomethacin 6.6611005569
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.9311564622
MESH:D005124 Eye Abnormalities Tretinoin 7.9316938888 9664655
MESH:D005234 Fatty Liver Cyclosporine 16.0419224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 16.0415345470
MESH:D005234 Fatty Liver pirinixic acid 16.0420131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 16.0414986274 19224547
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 7.4616534752 15751030 16611131 16002989 16513791
MESH:D052776 Female Urogenital Diseases Tamoxifen 7.4616709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1011858732
MESH:D005334 Fever Indomethacin 3.8011852909 10431976 17627676
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.1614745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.8119069698
MESH:D005354 Fibrosarcoma Indomethacin 4.5310962813
MESH:D005355 Fibrosis Cyclosporine 18.2112639820 12168785
MESH:D005355 Fibrosis Indomethacin 18.2117994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 18.2120067830
MESH:D005355 Fibrosis Tretinoin 18.2117994277
MESH:D005499 Folliculitis Indomethacin 4.7911298111
MESH:D005756 Gastritis Acetaminophen 9.9016983495
MESH:D005756 Gastritis Indomethacin 9.9015046732
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 11.5916452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 11.5916452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.858708960
MESH:D005909 Glioblastoma Fenretinide 15.0216187019
MESH:D005909 Glioblastoma Genistein 15.0216598420
MESH:D005909 Glioblastoma Indomethacin 15.0212870263
MESH:D005909 Glioblastoma Tretinoin 15.0217312396
MESH:D005910 Glioma Indomethacin 3.0818371953 16487511
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.9911849393
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2210696789
MESH:D006073 Gout Indomethacin 4.9811248219
MESH:D006258 Head and Neck Neoplasms Indomethacin 7.1015482327
MESH:D006258 Head and Neck Neoplasms Tretinoin 7.1016096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.7816084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 9.9420471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 9.9410048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 9.949664655 14991402
MESH:D006331 Heart Diseases Mitoxantrone 3.9016019553
MESH:D006333 Heart Failure pirinixic acid 6.1920558911
MESH:D006333 Heart Failure Selenium 6.1917162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.0515720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0111000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.2415633222
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.3315135802
MESH:D006529 Hepatomegaly Phenobarbital 12.3016109766
MESH:D006529 Hepatomegaly pirinixic acid 12.3019176532 19772884 18467677 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 12.3012621046 16120746 15340226
MESH:D006558 Herpes Genitalis Estradiol 4.6615709030
MESH:D006561 Herpes Simplex Etoposide 4.2010809021
MESH:D006689 Hodgkin Disease Etoposide 6.6415147373 18180244 16135485 16200630 17606976
MESH:D006689 Hodgkin Disease sodium arsenite 6.6412676792
MESH:D019584 Hot Flashes Estradiol 3.3817088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.6715340226 8697196 18606429 16354765 16959395
MESH:D006930 Hyperalgesia Acetaminophen 16.3516870215
MESH:D006930 Hyperalgesia Indomethacin 16.3512727271
MESH:D006930 Hyperalgesia oxaliplatin 16.3517418472
MESH:D006930 Hyperalgesia Tretinoin 16.3516870215
MESH:D034321 Hyperamylasemia Indomethacin 5.3417883296
MESH:D006940 Hyperemia Indomethacin 4.6412524144
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.2116778211
MESH:D006943 Hyperglycemia pirinixic acid 2.8720558911
MESH:D006949 Hyperlipidemias Indomethacin 3.8317546600
MESH:D006965 Hyperplasia Diethylstilbestrol 4.0812960047 14722030
MESH:D006973 Hypertension Cyclosporine 7.8210903974
MESH:D006973 Hypertension daidzein 7.8217169123
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.8218670907 18850075
MESH:D007021 Hypospadias Diethylstilbestrol 10.0516002989
MESH:D007021 Hypospadias Ethinyl Estradiol 10.0516569931 16945680
MESH:D007077 Ileal Diseases Indomethacin 4.6518306037 10574470
MESH:D007079 Ileitis Indomethacin 4.9810651667 16133968 10647630
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.0016133044
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.0415869954
MESH:D007246 Infertility Diethylstilbestrol 4.0115036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.1212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 5.8217937319
MESH:D007248 Infertility, Male sodium arsenite 5.8215346721 12646999
MESH:D007249 Inflammation Flavonoids 13.7717296493
MESH:D007249 Inflammation Indomethacin 13.777812673 3291741 12568917
MESH:D007249 Inflammation Progesterone 13.7715869954
MESH:D007249 Inflammation Tamoxifen 13.7719457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 13.7712200463 12878042
MESH:D007251 Influenza, Human Selenium 3.8216624496
MESH:D007333 Insulin Resistance bisphenol A 10.9116393666
MESH:D007333 Insulin Resistance Estradiol 10.9116393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 10.9116306350
MESH:D007410 Intestinal Diseases Indomethacin 8.6917329856 10210152 11713966 11686837 18236018 17994277 15831440 11855677 15610444
MESH:D007410 Intestinal Diseases Tretinoin 8.6917994277
MESH:D019586 Intracranial Hypertension Indomethacin 5.0015241188
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.8416580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.8417551590 15992940
MESH:D007579 Jejunal Diseases Indomethacin 4.6510574470 18306037 16133968
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0715604871
MESH:D007674 Kidney Diseases Acetaminophen 16.7612587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 16.768314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 16.7615618244
MESH:D007674 Kidney Diseases Indomethacin 16.7617190690
MESH:D007674 Kidney Diseases sodium arsenite 16.7620008137
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 8.9416518626
MESH:D007676 Kidney Failure, Chronic Selenium 8.9416518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 20.1916705839
MESH:D007680 Kidney Neoplasms Cyclosporine 20.1912371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 20.1914681315 15003126 16762066
MESH:D007680 Kidney Neoplasms Estradiol 20.1915610895
MESH:D007680 Kidney Neoplasms Tamoxifen 20.1918625569
MESH:D007859 Learning Disorders Diethylstilbestrol 3.7017184923
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.6112228301 10320625 11703811
MESH:D007938 Leukemia Genistein 5.7818980019 17468513
MESH:D007938 Leukemia Tretinoin 5.7817143497
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Mitoxantrone 3.6318172266
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.6510785260 16572323 15631656
MESH:D007951 Leukemia, Myeloid Tretinoin 3.3716932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 3.8118360721
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.8116294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 2.9116140955 16788101 19642359 19029980 17107899 16891316 17368321 17294898 17217047 19225113 17712046 17649720 9834237 17506722 17339181 12679006 16935935 16823087 17301526 17361223 15748426 19075265 16331271 16766008 19035177
MESH:D007964 Leukocytosis Indomethacin 5.0016537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.3417980183
MESH:D007972 Leukoplakia, Oral Fenretinide 5.6716707609
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.059224671
MESH:D008064 Lipidoses Tamoxifen 2.8917567588 15342952
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.3411479899
MESH:D008103 Liver Cirrhosis Phenobarbital 2.6921047994
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 10.1014659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 10.1017823541
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 10.1018194892
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 10.1015474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 10.1018564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 10.1012878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 10.1018397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 3.5919460945 16610002 19014921 16611625 19784758 12587719 12969438 11587558
MESH:D008107 Liver Diseases Phenobarbital 3.5919363144
MESH:D017114 Liver Failure, Acute Acetaminophen 2.9216871587 17185352
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 27.207678174
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 27.2020195826 21137059
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 27.2019389873 21295105
MESH:D008113 Liver Neoplasms Diethylstilbestrol 27.2015890375 16712894
MESH:D008113 Liver Neoplasms Phenobarbital 27.208742319 21047994 19073162 19812893 15975961 19482888
MESH:D008113 Liver Neoplasms pirinixic acid 27.2015890375 16377806 20007298
MESH:D008113 Liver Neoplasms sodium arsenite 27.2016712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 27.2016684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 27.2016984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 12.222876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 12.2218164116
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 12.221399818 18308698 6150874 2563599 17172636
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 12.2212151625
MESH:D008171 Lung Diseases sodium arsenite 2.9319095001
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 7.8718569708 20064080 18816296 17053015 20464547 6695378 20135361 18520028 20869020
MESH:D008175 Lung Neoplasms bexarotene 7.8717849452
MESH:D008175 Lung Neoplasms Indomethacin 7.8716537180 11497255 11053908
MESH:D008175 Lung Neoplasms sodium arsenite 7.8717077188 15276417 17306315 19931552 16712894
MESH:D008175 Lung Neoplasms Tamoxifen 7.8718625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 7.8719555203 11884234
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.7815166399
MESH:D008223 Lymphoma Diethylstilbestrol 7.0415700306
MESH:D008223 Lymphoma Etoposide 7.0412854902 12556972
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.7911161223
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.1416002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.3919428831
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 24.8519196723 15591091 19196722
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 24.8511408345 11807958 17203775 16891317
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 24.8510697514
MESH:D008325 Mammary Neoplasms, Experimental Genistein 24.8514578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 24.8511408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Selenium 24.8515318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 24.8519196722 11731420 19196723 14580682 16827153
MESH:D020149 Manganese Poisoning Estradiol 11.4019453300
MESH:D020149 Manganese Poisoning Tamoxifen 11.4019453300
MESH:D008527 Medulloblastoma Tretinoin 2.6317453147
MESH:D008545 Melanoma Fenretinide 6.7116270382
MESH:D008545 Melanoma sodium arsenite 6.7119082730 16487513
MESH:D008545 Melanoma Tamoxifen 6.7119393235 12393984
MESH:D008545 Melanoma Tretinoin 6.7116752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.8115990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.2119513568
MESH:D008591 Meningomyelocele Tretinoin 4.0616940565
MESH:D008654 Mesothelioma Selenium 2.6415107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.4116801185
MESH:D008881 Migraine Disorders Indomethacin 3.4111903285
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 12.8916381670
MESH:D009062 Mouth Neoplasms Fenretinide 12.8916274795
MESH:D009062 Mouth Neoplasms Indomethacin 12.8912636206
MESH:D009135 Muscular Diseases pirinixic acid 3.1516239165
MESH:D009190 Myelodysplastic Syndromes Tretinoin 2.8717596541
MESH:D009203 Myocardial Infarction Genistein 5.1417141266
MESH:D009203 Myocardial Infarction pirinixic acid 5.1419151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.7312213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 12.5516810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 12.5517141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 12.5516411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.1117484760
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.497678174 18551238
MESH:D009362 Neoplasm Metastasis Indomethacin 5.4311239499 11053908 16537180
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.4319393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3919410462
MESH:D009369 Neoplasms Benzo(a)pyrene 21.1511141357
MESH:D009369 Neoplasms Diethylstilbestrol 21.1515313581
MESH:D009369 Neoplasms Fenretinide 21.1515958647 17353921
MESH:D009369 Neoplasms Mitoxantrone 21.1516640825
MESH:D009369 Neoplasms pirinixic acid 21.1517405874
MESH:D009369 Neoplasms sodium arsenite 21.1511559025
MESH:D009369 Neoplasms Tretinoin 21.1516594593 16946489
MESH:D009374 Neoplasms, Experimental Indomethacin 8.0910663608 15625704
MESH:D009374 Neoplasms, Experimental sodium arsenite 8.0920056578
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 9.6919196722
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 9.6919189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.3717289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.9818481113 19348381
MESH:D009421 Nervous System Malformations bisphenol A 33.7216427766 11399458
MESH:D009421 Nervous System Malformations Diethylstilbestrol 33.7211399458
MESH:D009421 Nervous System Malformations Estradiol 33.7216427766 11399458
MESH:D009421 Nervous System Malformations Genistein 33.7216427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 33.7214600291
MESH:D009421 Nervous System Malformations Tretinoin 33.729125849
MESH:D009436 Neural Tube Defects sodium arsenite 6.5112854658
MESH:D009436 Neural Tube Defects Tretinoin 6.519142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.4118514411
MESH:D019636 Neurodegenerative Diseases Indomethacin 7.4112349958
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 5.3116303764
MESH:D009765 Obesity pirinixic acid 1.7220558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.796374098
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.1216049721
MESH:D010003 Osteoarthritis Indomethacin 3.447009135
MESH:D010018 Osteomalacia Phenobarbital 4.0017016548
MESH:D010024 Osteoporosis Genistein 3.0319401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.7516169203
MESH:D010049 Ovarian Diseases bisphenol A 4.6211985600
MESH:D010051 Ovarian Neoplasms Estradiol 17.2319401270
MESH:D010051 Ovarian Neoplasms Fenretinide 17.2316133793
MESH:D010051 Ovarian Neoplasms Genistein 17.2319005980
MESH:D010051 Ovarian Neoplasms Progesterone 17.2317393432 16525653
MESH:D010051 Ovarian Neoplasms sodium arsenite 17.2317306315 15276417
MESH:D010051 Ovarian Neoplasms Tretinoin 17.2316936753
MESH:D010146 Pain Acetaminophen 13.7516870215
MESH:D010146 Pain AM 251 13.7518987195
MESH:D010146 Pain Indomethacin 13.7517627676 13679232 17440234 3291741
MESH:D010146 Pain Tretinoin 13.7516870215
MESH:D010149 Pain, Postoperative Indomethacin 4.3118702446 12538197
MESH:D010190 Pancreatic Neoplasms AM 251 14.8616500647
MESH:D010190 Pancreatic Neoplasms Etoposide 14.8619003803
MESH:D010190 Pancreatic Neoplasms Fenretinide 14.8615580305
MESH:D010190 Pancreatic Neoplasms Phenobarbital 14.8616965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 14.8615976015
MESH:D010195 Pancreatitis Indomethacin 3.5917883296 15028970
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3511578682
MESH:D010212 Papilloma Hydrogen Peroxide 3.7312065085
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.3416537180
MESH:D020734 Parkinsonian Disorders Indomethacin 3.8012349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.3411903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8712520081
MESH:D010437 Peptic Ulcer Indomethacin 4.7811148446
MESH:D010518 Periodontitis Indomethacin 4.5417225004
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.7914722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.3116977796 15687265
MESH:D010954 Plasmacytoma Selenium 4.5115087411
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2118163543
MESH:D011230 Precancerous Conditions Cyclosporine 7.9512371664
MESH:D011230 Precancerous Conditions Phenobarbital 7.952563599
MESH:D047928 Premature Birth Indomethacin 4.7717000239
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 14.1510548101
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 14.1517184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 14.1511222880 11896295 11399792 11118676
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 9.4620887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.4620887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.8117292933
MESH:D011471 Prostatic Neoplasms bisphenol A 2.8116740699
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.8117136230 15846301 15046698
MESH:D011471 Prostatic Neoplasms Estradiol 2.8116740699
MESH:D011471 Prostatic Neoplasms Etoposide 2.8117172428
MESH:D011471 Prostatic Neoplasms Fenretinide 2.8117024972
MESH:D011471 Prostatic Neoplasms Genistein 2.8115256057 16925846 15378649
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.8116039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.8115067354
MESH:D011507 Proteinuria Indomethacin 8.2111849393
MESH:D011507 Proteinuria Tretinoin 8.2116636307
MESH:D011537 Pruritus Ethinyl Estradiol 2.9515861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 4.1212752131
MESH:D011565 Psoriasis Cyclosporine 2.1016882103
MESH:D011625 Pterygium Tretinoin 4.4216723453
MESH:D011629 Puberty, Precocious bisphenol A 4.4210548101
MESH:D015427 Reperfusion Injury pirinixic acid 2.2019058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4918990726
MESH:D012162 Retinal Degeneration Fenretinide 4.1316303925
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.7616116481 16283617
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7218045962
MESH:D012512 Sarcoma, Ewing's Etoposide 4.3614601052
MESH:D012640 Seizures 2,6-dinitrotoluene 5.1018551238
MESH:D012640 Seizures Phenobarbital 5.103137016 4039156 11442880 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.456407741
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 24.4519755658 10029692
MESH:D012878 Skin Neoplasms Fenretinide 24.4516467112
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 24.4512065085
MESH:D012878 Skin Neoplasms sodium arsenite 24.4518572023 19524636
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 24.458532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 24.4516192470
MESH:D012878 Skin Neoplasms Tretinoin 24.4516467112
MESH:D013088 Spermatocele Diethylstilbestrol 17.9616002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 17.9616709447
MESH:D013088 Spermatocele Tamoxifen 17.9616709447
MESH:D013119 Spinal Cord Injuries Progesterone 9.6516503802 15862959
MESH:D013119 Spinal Cord Injuries Tamoxifen 9.6519457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.5112854658
MESH:D013272 Stomach Diseases Indomethacin 4.0517638125 17207306 16184426 10215738 16113693 10486359 15038085 17160473 10192188 15472012 16280098 18209964 18545984
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.1820155912 2093021
MESH:D013274 Stomach Neoplasms Indomethacin 3.1815609394
MESH:D013274 Stomach Neoplasms Tretinoin 3.1817261132
MESH:D013276 Stomach Ulcer Indomethacin 3.2710878458 17977527 15138204 16169175 15255614 14567935 16755016 10423059 12077510 12787963 17918041 18726076 18087811 12467913 18543354 11595431 15104355 12498302 11595415 16631530 17135157 18209962 11729361 18193104 17627676 18181030 16397915 17654042 18299717 17657623 1323529 16934674 11906479 17895592 11523592 11145282 18431645 18237397 10750652 12500499 16252198 16150113
MESH:D019966 Substance-Related Disorders bisphenol A 3.6216045194 16684133
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8515669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5312697716
MESH:D013964 Thyroid Neoplasms Indomethacin 10.4514736730 11352223 18791128
MESH:D013964 Thyroid Neoplasms Phenobarbital 10.451399818
MESH:D013964 Thyroid Neoplasms Tretinoin 10.4516026305 17045167
MESH:D013978 Tibial Fractures Estradiol 4.3119048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.4716051514
MESH:D014376 Tuberculosis Tretinoin 3.0016040207
MESH:D014456 Ulcer Indomethacin 4.5310574470 17380554
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 17.8916049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 17.8917053015
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 17.8916712894 17306315 16452187
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 17.8916720286
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 17.8916712894 17306315 16452187 11723127
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 17.898653321 17572228 16712894
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 3.9510091137
MESH:D014581 Urticaria Acetaminophen 2.6410982225
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 20.0516175088
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 20.0516154183
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 20.0511813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 20.0516129372
MESH:D014591 Uterine Diseases bisphenol A 12.5714652134
MESH:D014591 Uterine Diseases Diethylstilbestrol 12.5714652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 8.3115809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 8.3114692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.2416752155
MESH:D014605 Uveitis Cyclosporine 3.611336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.0816513791 16002989
MESH:D014652 Vascular Diseases sodium arsenite 4.0617056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2212125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2115869587 14671159
MESH:D014820 Vitiligo Tretinoin 3.7116761959
MESH:D014839 Vomiting Indomethacin 4.3711897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8715886252
MESH:D009396 Wilms Tumor Tretinoin 3.6616287080
MESH:D014985 Xerophthalmia Cyclosporine 4.0717120751
Pathway ID Pathway Name
REACT:19419 Amino acid and oligopeptide SLC transporters
REACT:604 Hemostasis
REACT:13 Metabolism of amino acids and derivatives
REACT:15518 Transmembrane transport of small molecules
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA35923
    • Releated gene ID Related gene Name
    PA35923SLC7A5
    No data
    Releated drug ID Related drug Name
    PA448055l-alanine
    PA448478l-arginine
    PA450197l-leucine
    PA450280l-lysine
    PA451330l-serine
    PA451822l-tyrosine
    PA451843l-valine
    PA451590taurine
    PA10323l-tryptophan
    PA449789glycine
    PA449173l-cysteine
    PA451125l-proline
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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