AutismKB 2.0

Annotation Detail for TAF15


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Basic Information Top
Gene Symbol:TAF15 ( Npl3,RBP56,TAF2N,TAFII68,hTAFII68 )
Gene Full Name: TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
Band: 17q12
Quick LinksEntrez ID:8148; OMIM: 601574; Uniprot ID:RBP56_HUMAN; ENSEMBL ID: ENSG00000172660; HGNC ID: 11547
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Desease IDDesease Name
Cancers
Cancers of soft tissues and bone
H00053Extraskeletal myxoid chondrosarcoma
No data
No data
No data
Desease Name
Chondrosarcoma, extraskeletal myxoid
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of TAF15 mRNAaffects expression 17562736
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TAF15 mRNAdecreases expression 20018196
C011890 kojic acid kojic acid results in decreased expression of TAF15 mRNAdecreases expression 16595896
D013755 Tetradecanoylphorbol Acetate [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TAF15 mRNAaffects cotreatment|affects expression 16979875
D015032 Zinc [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TAF15 mRNAaffects cotreatment|affects expression 16979875
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000169 Acrodermatitis Zinc 5.9417190629 16889938 17202136
MESH:D000544 Alzheimer Disease Zinc 2.8117119284 16325427 16410023 16580781
MESH:D000755 Anemia, Sickle Cell Zinc 5.3416916123
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D001249 Asthma Zinc 3.0417085522
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001930 Brain Injuries Zinc 5.1717109824
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.403084413
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 5.4018922899
MESH:D002294 Carcinoma, Squamous Cell Zinc 5.4016543248
MESH:D002318 Cardiovascular Diseases Zinc 3.8916936243
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.9620889678
OMIM:612237 CHONDROSARCOMA, EXTRASKELETAL MYXOID marker/mechanism
MESH:D019465 Craniofacial Abnormalities Zinc 2.4419302082
MESH:D003920 Diabetes Mellitus Zinc 4.5316479319
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6619370779 19739265 19164858 19416960 10774834 11421492 12594235 16781746 2444490 12540782 15968718 11529661 17562736 17522070 15619225 14725611 11739529 11743745 19923254 12958197 12392966 14986274 19420014 19085960 16393943 11287661 16485898 12153990 16081117 17906064 10663392 14550746 16227642 18713872 11834606 16177239 12705907 10915739 16109766 11461765 18071297
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D004487 Edema Tetradecanoylphorbol Acetate 3.989599246 16716910 8273558 7812673 11698051 8113982 15177302
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.9020426865
MESH:D004938 Esophageal Neoplasms Zinc 4.9016543248
MESH:D005756 Gastritis Acetaminophen 13.3016983495
MESH:D005756 Gastritis Zinc 13.3017241300
MESH:D006130 Growth Disorders Zinc 4.1717217573
MESH:D006333 Heart Failure Zinc 3.8117162251
MESH:D006335 Heart Injuries Zinc 6.3817074742
MESH:D016481 Helicobacter Infections Zinc 4.9417241300
MESH:D006527 Hepatolenticular Degeneration Zinc 5.1717276780
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 3.2415177302 11698051 7812673 7562506 8273558
MESH:D007511 Ischemia Zinc 5.1116584753
MESH:D007674 Kidney Diseases Acetaminophen 6.7712587719 15629191
MESH:D007674 Kidney Diseases Zinc 6.7716960431
MESH:D007676 Kidney Failure, Chronic Zinc 4.7916518626
MESH:D008107 Liver Diseases Acetaminophen 1.6912969438 16611625 11587558 19460945 19784758 12587719 19014921 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5816871587 17185352
MESH:D008114 Liver Neoplasms, Experimental kojic acid 3.5318544905
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 2.4811807781
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 7.238985016
MESH:D008325 Mammary Neoplasms, Experimental Zinc 7.2312773700
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 3.2315976015
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 4.7818922899 12065085 18404319 8330346
MESH:D011225 Pre-Eclampsia Zinc 4.4517114810
MESH:D011471 Prostatic Neoplasms Zinc 3.7616700911 12429649 16517595 16606632
MESH:D012162 Retinal Degeneration Zinc 4.3916584753
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 3.4211807781 18404319 12065085 8330346 8985016
MESH:D014062 Tongue Neoplasms Zinc 4.7516543248
MESH:D014581 Urticaria Acetaminophen 3.3810982225
Pathway ID Pathway Name
KEGG:03022 Basal transcription factors
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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