AutismKB 2.0

Annotation Detail for VOPP1


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Basic Information Top
Gene Symbol:VOPP1 ( DKFZp564K0822,ECOP,FLJ20532,GASP )
Gene Full Name: vesicular, overexpressed in cancer, prosurvival protein 1
Band: 7p11.2
Quick LinksEntrez ID:81552; OMIM: 611915; Uniprot ID:VOPP1_HUMAN; ENSEMBL ID: ENSG00000154978; HGNC ID: 34518
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of VOPP1 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of VOPP1 mRNAincreases expression 19482888
C010327 salinomycin salinomycin results in decreased expression of VOPP1 mRNAdecreases expression 19682730
D014635 Valproic Acid Valproic Acid results in increased expression of VOPP1 mRNAincreases expression 19101580
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 11.146195326
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 11.148875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.4119490988
MESH:D018248 Adenoma, Liver Cell Phenobarbital 4.7117620307
MESH:D000550 Amblyopia Valproic Acid 6.1017688650
MESH:D001008 Anxiety Disorders Valproic Acid 3.9417497229
MESH:D001321 Autistic Disorder Valproic Acid 1.9816609825 17157402 19232924 18316065 17507914 18177632 15238991 17688650 18940202 20603192 18775368 18558336 18985861 19460635 18396377
MESH:D001714 Bipolar Disorder Valproic Acid 3.2617594078 20046352
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.668888407
MESH:D001943 Breast Neoplasms salinomycin 3.3119682730
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 1.956705139 1701930 20935162 17173139 20007298
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.904080065
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.8320734317
MESH:D019465 Craniofacial Abnormalities Valproic Acid 1.9117688650 8888407 16575769
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 2.261733752 19641884
MESH:D004421 Dystonia Phenobarbital 12.251851702
MESH:D004421 Dystonia Valproic Acid 12.251851702
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 13.063659116
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 13.063659116 17275665
MESH:D004828 Epilepsies, Partial Phenobarbital 13.083922381 11558140
MESH:D004828 Epilepsies, Partial Valproic Acid 13.083922381 16628512
MESH:D004827 Epilepsy Phenobarbital 7.3120417680
MESH:D004827 Epilepsy Valproic Acid 7.3118234410 20417680
MESH:D004832 Epilepsy, Absence Phenobarbital 10.286401628
MESH:D004832 Epilepsy, Absence Valproic Acid 10.286254150 7562514 6426943
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 13.577750514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 13.577750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 13.093659116
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 13.093659116
MESH:D005234 Fatty Liver Valproic Acid 3.7819224547 14986274
MESH:D005315 Fetal Diseases Valproic Acid 5.7516575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.7118558336 8888407
MESH:D006529 Hepatomegaly Phenobarbital 4.1316109766
MESH:D006849 Hydrocephalus Valproic Acid 5.6117688650
MESH:D015470 Leukemia, Myeloid, Acute marker/mechanism 18206229
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.2016294345 17596541
MESH:D008103 Liver Cirrhosis Phenobarbital 3.1021047994
MESH:D008107 Liver Diseases Phenobarbital 2.2519363144
MESH:D008113 Liver Neoplasms Phenobarbital 2.4319812893 21047994 8742319 19073162 15975961 19482888
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 2.952563599 17172636 1399818 18308698 6150874
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 5.1317228818
MESH:D008325 Mammary Neoplasms, Experimental salinomycin 4.0319682730
MESH:D008881 Migraine Disorders Valproic Acid 3.5018803445 18765137
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.518888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3717596541
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 5.2217484760
MESH:D009436 Neural Tube Defects Valproic Acid 3.3916359493 8888407
MESH:D010018 Osteomalacia Phenobarbital 5.1117016548
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.6116965848
MESH:D011230 Precancerous Conditions Phenobarbital 4.042563599
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 4.5720603192
MESH:D019310 Pseudolymphoma Phenobarbital 15.3012752131
MESH:D019310 Pseudolymphoma Valproic Acid 15.3012752131 11422049
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.7019155313
MESH:D012559 Schizophrenia Valproic Acid 2.1115737665 19110320
MESH:D012640 Seizures Phenobarbital 6.9816876388 3137016 11442880 4039156
MESH:D012640 Seizures Valproic Acid 6.9816876388 3137016 11044598 14763951 17978042 15475178 1511512 11738929
MESH:D003294 Seizures, Febrile Phenobarbital 5.566407741
MESH:D016135 Spinal Dysraphism Valproic Acid 4.1319490988
MESH:D013226 Status Epilepticus Valproic Acid 5.4112833885
MESH:D013964 Thyroid Neoplasms Phenobarbital 3.391399818
MESH:D014178 Translocation, Genetic Valproic Acid 6.1017262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 5.263119515
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.308888407
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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