AutismKB 2.0

Annotation Detail for CAMK2G


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Basic Information Top
Gene Symbol:CAMK2G ( CAMK,CAMK-II,CAMKG,FLJ16043,MGC26678 )
Gene Full Name: calcium/calmodulin-dependent protein kinase II gamma
Band: 10q22.2
Quick LinksEntrez ID:818; OMIM: 602123; Uniprot ID:KCC2G_HUMAN; ENSEMBL ID: ENSG00000148660; HGNC ID: 1463
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04912GnRH signaling pathway
hsa04916Melanogenesis
hsa04012ErbB signaling pathway
hsa04720Long-term potentiation
hsa04020Calcium signaling pathway
hsa04310Wnt signaling pathway
hsa04722Neurotrophin signaling pathway
hsa04971Gastric acid secretion
hsa04114Oocyte meiosis
hsa05214Glioma
hsa04740Olfactory transduction
Pathway IDPathway Name
Synaptic Transmission
Pathway IDPathway Name
200005BCR signaling pathway
200180N-cadherin signaling events
Pathway IDPathway Name
P00037Ionotropic glutamate receptor pathway
P00031Inflammation mediated by chemokine and cytokine signaling pathway
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1904Diabetes mellitus
2051Leukemia
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of CAMK2G mRNAdecreases expression 19933214
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of CAMK2G mRNAdecreases expression 12958071
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of CAMK2G mRNAdecreases expression 18648102
C103303 alitretinoin alitretinoin results in increased expression of CAMK2G mRNAincreases expression 16648578
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CAMK2G mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of CAMK2G mRNAincreases expression 20458559
C095105 bexarotene bexarotene results in increased expression of CAMK2G mRNAincreases expression 16648578
D004958 Estradiol Estradiol affects the expression of CAMK2G mRNAaffects expression 14699072
D000431 Ethanol Ethanol results in decreased expression of CAMK2G mRNAdecreases expression 16098508
C063302 KN 62 KN 62 results in decreased phosphorylation of and results in decreased activity of CAMK2G proteindecreases activity|decreases phosphorylation 17431504
C008493 methylselenic acid methylselenic acid results in increased expression of CAMK2G mRNAincreases expression 18548127
C006253 pirinixic acid pirinixic acid results in decreased expression of CAMK2G mRNAdecreases expression 18445702
C009277 sodium arsenate sodium arsenate results in decreased expression of CAMK2G mRNAdecreases expression 12727804
C017947 sodium arsenite sodium arsenite results in decreased expression of CAMK2G mRNAdecreases expression 12727804
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of CAMK2G mRNAdecreases expression 19933214
D024505 Tocopherols Tocopherols results in increased expression of CAMK2G mRNAincreases expression 17654050
D014212 Tretinoin Tretinoin inhibits the reaction [CAMK2G protein binds to CEBPE promoter]affects binding|decreases reaction 17431504
D014635 Valproic Acid Valproic Acid results in increased expression of CAMK2G mRNAincreases expression 19101580
C025643 vinclozolin vinclozolin affects the expression of CAMK2G mRNAaffects expression 19015723
D014810 Vitamin E Vitamin E results in decreased expression of CAMK2G mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Ethanol 13.7718926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 13.7711752688 14514962 15322242
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 13.778875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.8419490988
MESH:D000138 Acidosis Ammonium Chloride 10.1818287403
MESH:D000138 Acidosis Ethanol 10.1811192467
MESH:D055371 Acute Lung Injury pirinixic acid 3.0318653653
MESH:D000230 Adenocarcinoma arsenic trioxide 4.3219825857 11798837
MESH:D000230 Adenocarcinoma Estradiol 4.3211473722
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.703712494
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.6216434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.6216835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.6215276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.8216712894 17306315
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 5.2415451040 15451039
MESH:D000505 Alopecia Tretinoin 3.5415955085
MESH:D000550 Amblyopia Valproic Acid 5.1517688650
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8711748828
MESH:D000853 Anophthalmos Ethanol 4.7315513904
MESH:D001008 Anxiety Disorders Ethanol 14.4411141031
MESH:D001008 Anxiety Disorders Valproic Acid 14.4417497229
MESH:D001008 Anxiety Disorders vinclozolin 14.4419015723
MESH:D001169 Arthritis, Experimental Tretinoin 3.0216412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2416292516
MESH:D001249 Asthma Tretinoin 2.3216456186
MESH:D001321 Autistic Disorder Valproic Acid 2.0117157402 16609825 17507914 18775368 17688650 18985861 18396377 15238991 18940202 18177632 19460635 20603192 19232924 18316065 18558336
MESH:D001471 Barrett Esophagus Tretinoin 4.3216935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.941440618 11289319
MESH:D001714 Bipolar Disorder Valproic Acid 3.0320046352 17594078
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 21.2716206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 21.2719483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 21.2712125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 21.2716206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 7.8315746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 7.838888407
MESH:D001943 Breast Neoplasms alitretinoin 2.3316344269
MESH:D001943 Breast Neoplasms bexarotene 2.3316818667 16344269
MESH:D001943 Breast Neoplasms Estradiol 2.3316675129 18497071 12948864 19861407 14630087 17261762 17289903 17018787
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.3320435547
MESH:D001943 Breast Neoplasms Tretinoin 2.3316873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.5016813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.2411589617
MESH:D002056 Burns Ethanol 4.5616374292
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.3816111702
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.8416050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7316835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.0816168501
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 11.227296757 3581430
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 11.2216217749 15073043 14691202 11135700 15553829
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.2216924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 11.2215289165 15763234 18788625
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 11.2217306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 11.221917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.2016247446
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.7919014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.637296757
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.0412490120
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 4.6018572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.6016051514 16096774
MESH:D006332 Cardiomegaly Ethanol 6.6819332462
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.6818670907 18850075 16120746
MESH:D002386 Cataract Tretinoin 3.0417460283
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 10.857505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 10.8518566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 10.8520056578 19524636
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.5016129372
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.6820734317
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0816835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 7.6219486331 9022650
MESH:D002779 Cholestasis pirinixic acid 7.6219176532
MESH:D002822 Choriocarcinoma Tretinoin 5.0816461808
MESH:D002971 Cleft Lip Ethanol 3.5415513904
MESH:D002972 Cleft Palate Ethanol 9.6315513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 9.6315340226 8697196 16354765 15668235 12621046
MESH:D002972 Cleft Palate Tretinoin 9.639407595
MESH:D003092 Colitis Tretinoin 3.6217035595
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9814669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 4.1012609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 11.6810525206
MESH:D019465 Craniofacial Abnormalities Ethanol 11.6810194807 15451039 11873399 11198716 15513904 19302082 15451040
MESH:D019465 Craniofacial Abnormalities sodium arsenate 11.6810525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 11.6810048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 11.689142499 8800419 9211117 10589399 9224671 9125849 16925845 14991402 9664655 17551590
MESH:D019465 Craniofacial Abnormalities Valproic Acid 11.6816575769 8888407 17688650
MESH:D019465 Craniofacial Abnormalities Vitamin E 11.6819769572
MESH:D003456 Cryptorchidism vinclozolin 4.2514966744
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.0115213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.7218759878 12868966 8970840 8156756 11298694 14531868 2524372 11906362
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3818249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.413621924 2952479
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6517107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.3319279558
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 11.7611289319 6679447 18648102 16192314 6482804 7440962 8291058 9328219 9653073 1440618 18289764 9022650 18692083
MESH:D056486 Drug-Induced Liver Injury Ethanol 11.7611566570
MESH:D056486 Drug-Induced Liver Injury sodium arsenate 11.7618186108
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.7620420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 11.7619641884 1733752
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6911462148
MESH:D004421 Dystonia Valproic Acid 3.961851702
MESH:C538011 Eales disease Vitamin E 4.629068938
MESH:D004487 Edema pirinixic acid 6.2712083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.2712711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.6718230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 11.6718230668
MESH:D016889 Endometrial Neoplasms Estradiol 7.2219148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Tretinoin 7.2216569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.949294722 10568697
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.073659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 3.8416628512 3922381
MESH:D004827 Epilepsy Valproic Acid 2.8920417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.516426943 7562514 6254150
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.217750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.983659116
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 7.183581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 7.1812903497
MESH:D004938 Esophageal Neoplasms Ethanol 7.1816704527
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.6111564622
MESH:D005124 Eye Abnormalities Tretinoin 8.619664655 16938888
MESH:D005234 Fatty Liver arsenic trioxide 18.1315073043
MESH:D005234 Fatty Liver Ethanol 18.1316409862 19236843 18620774
MESH:D005234 Fatty Liver pirinixic acid 18.1319236843 20131406
MESH:D005234 Fatty Liver Valproic Acid 18.1319224547 14986274
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.5817920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 5.2110194807 15451040 16946407 15513904
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3711858732
MESH:D005315 Fetal Diseases Valproic Acid 4.8116575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.0418558336 8888407
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.946705139
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.3320067830
MESH:D005355 Fibrosis Tretinoin 8.3317994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.1816904648
MESH:D005756 Gastritis Ethanol 4.6115046732
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.8516973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.2216417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.5916452187
MESH:D005909 Glioblastoma Tretinoin 2.9517312396
MESH:D018149 Glucose Intolerance sodium arsenate 5.0019446573
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.957505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5110696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.1216096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.0816084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.8711294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 10.8714991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin E 10.8716080930
MESH:D006333 Heart Failure pirinixic acid 2.4820558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2511000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.436705139
MESH:D006529 Hepatomegaly pirinixic acid 7.9718467677 16221962 19176532 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.9716120746 15340226 12621046
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6716490937 16863852
MESH:D006558 Herpes Genitalis Estradiol 4.9515709030
MESH:D006689 Hodgkin Disease sodium arsenite 3.0812676792
MESH:D019584 Hot Flashes Estradiol 9.7817088409
MESH:D019584 Hot Flashes Vitamin E 9.7814716179
MESH:D006849 Hydrocephalus Valproic Acid 4.7817688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9615340226 16959395 18606429 16354765 8697196
MESH:D006930 Hyperalgesia Ethanol 7.7618783367
MESH:D006930 Hyperalgesia Tretinoin 7.7616870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.4816778211
MESH:D006943 Hyperglycemia pirinixic acid 3.1020558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.8515034207
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8718850075 18670907
MESH:D007248 Infertility, Male sodium arsenite 6.6512646999 15346721
MESH:D007248 Infertility, Male vinclozolin 6.6516467254
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.8112200463 12878042
MESH:D007251 Influenza, Human Vitamin E 4.1316624496
MESH:D007333 Insulin Resistance Estradiol 7.0016627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 7.0016306350
MESH:D007410 Intestinal Diseases Tretinoin 3.6817994277
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.948074119 9022650
MESH:D007569 Jaw Abnormalities Ethanol 16.7115513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 16.7116580747
MESH:D007569 Jaw Abnormalities Tretinoin 16.7117551590 15992940
MESH:D017492 Keratosis, Seborrheic alitretinoin 5.5516144296
MESH:D007674 Kidney Diseases Estradiol 9.8215618244
MESH:D007674 Kidney Diseases sodium arsenite 9.8220008137
MESH:D007674 Kidney Diseases Vitamin E 9.8212488133
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 7.116582329
MESH:D007680 Kidney Neoplasms Estradiol 7.1115610895
MESH:D007859 Learning Disorders Ethanol 4.1215451040
MESH:D007938 Leukemia arsenic trioxide 6.2015070760
MESH:D007938 Leukemia Tretinoin 6.2017143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.7117077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.2216972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.2019077051
MESH:D007951 Leukemia, Myeloid Tretinoin 9.2016482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 6.0216467208 19850784 20471514 17050201 16968895
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 6.0216294345 17596541 19850784
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 6.0216294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.4417869043 16966277 15622746 19642359 12018890 16891316 12679006 11468182 16330433 19075265 15748426 15213294 12712474 16112521 17712046 11161223 9834237 16823087 15336539 19225113 16331271 19035177 17217047 17649720 17107899
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.4417107899 19075265 19035177 17649720 16766008 17294898 15748426 9834237 16331271 12679006 17339181 17712046 19642359 17506722 17217047 16788101 16935935 16823087 16140955 17361223 17368321 16891316 19225113 19029980 17301526
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.2716882451
MESH:D007984 Leydig Cell Tumor vinclozolin 4.6516417039
MESH:D017880 Limb Deformities, Congenital Ethanol 8.1017676605
MESH:D017880 Limb Deformities, Congenital Tretinoin 8.109224671
MESH:D008103 Liver Cirrhosis Ethanol 3.3215289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 5.0118295389
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.149327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 8.6014659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 8.6018166357
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 8.6015474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 8.6012878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 8.6018397230 16248980
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 8.6016169303
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.5617347304 17207112
MESH:D008113 Liver Neoplasms arsenic trioxide 10.4114682389
MESH:D008113 Liver Neoplasms pirinixic acid 10.4115890375 20007298 16377806
MESH:D008113 Liver Neoplasms sodium arsenite 10.4116712894 15276417
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 10.4116984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 9.48598648 3712494 6587162 1399818
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 9.4820377131
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.4812151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.2815213294
MESH:D008171 Lung Diseases sodium arsenite 7.2419095001
MESH:D008171 Lung Diseases Vitamin E 7.2416863852
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.1817228818
MESH:D008175 Lung Neoplasms alitretinoin 8.4316413115
MESH:D008175 Lung Neoplasms arsenic trioxide 8.4319825857 11798837
MESH:D008175 Lung Neoplasms bexarotene 8.4317849452
MESH:D008175 Lung Neoplasms sodium arsenite 8.4319931552 15276417 17077188 16712894 17306315
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.4319555203 11884234
MESH:D008175 Lung Neoplasms Vitamin E 8.4311062179
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 5.0611161223
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 9.9119196722 19196723 15591091
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 9.9111408345 11807958 17203775 16891317
MESH:D008325 Mammary Neoplasms, Experimental Tocopherols 9.9117927505
MESH:D020149 Manganese Poisoning Estradiol 4.4019453300
MESH:D008527 Medulloblastoma Tretinoin 2.7517453147
MESH:D008545 Melanoma sodium arsenite 3.2919082730 16487513
MESH:D008545 Melanoma Tretinoin 3.2916752155
MESH:D008569 Memory Disorders Ethanol 4.1015451040 18411066
MESH:D008591 Meningomyelocele Tretinoin 4.3416940565
MESH:D008654 Mesothelioma Tocopherols 4.0715878867
MESH:D008881 Migraine Disorders Valproic Acid 3.1318765137 18803445
MESH:D009101 Multiple Myeloma arsenic trioxide 3.0411468182 19417148 19549372 14977855 15949261
MESH:D009135 Muscular Diseases pirinixic acid 3.4216239165
MESH:D009139 Musculoskeletal Abnormalities sodium arsenate 10.4118186108
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 10.418888407
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.5918349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 12.0216882451 16105982
MESH:D009190 Myelodysplastic Syndromes Tretinoin 12.0217596541
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 12.0217596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.1119151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9512213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.0216810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.0216411023
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.8716624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.433581430
MESH:D009369 Neoplasms alitretinoin 11.5416946489
MESH:D009369 Neoplasms pirinixic acid 11.5417405874
MESH:D009369 Neoplasms sodium arsenite 11.5411559025
MESH:D009369 Neoplasms Tretinoin 11.5416594593 16946489
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.5820056578
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 4.7019196722
MESH:D009389 Neovascularization, Pathologic Estradiol 3.6517289903
MESH:D009421 Nervous System Malformations Estradiol 15.8311399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 15.8314600291
MESH:D009421 Nervous System Malformations Tretinoin 15.839125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 27.646679447
MESH:D009436 Neural Tube Defects arsenic trioxide 27.6410525206
MESH:D009436 Neural Tube Defects sodium arsenate 27.6410525206 19446573 18186108 11749123
MESH:D009436 Neural Tube Defects sodium arsenite 27.6412854658
MESH:D009436 Neural Tube Defects Tretinoin 27.649142499
MESH:D009436 Neural Tube Defects Valproic Acid 27.648888407 16359493
MESH:D009765 Obesity pirinixic acid 1.7920558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.346482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.943988306
MESH:D010051 Ovarian Neoplasms arsenic trioxide 11.0619769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms Estradiol 11.0619401270
MESH:D010051 Ovarian Neoplasms sodium arsenite 11.0615276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 11.0616936753
MESH:D010146 Pain Tretinoin 2.8316870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 8.5015580305
MESH:D010190 Pancreatic Neoplasms Ethanol 8.5012384795
MESH:D010190 Pancreatic Neoplasms Tretinoin 8.5015976015
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.407296757
MESH:D010235 Paraganglioma arsenic trioxide 4.0819927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1712520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.396228378
MESH:D017499 Porokeratosis alitretinoin 5.9216144296
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4718163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 15.7511896295 11118676 11399792 11222880
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 15.7520603192
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 15.7518220299 18042343 19015723
MESH:D011469 Prostatic Diseases vinclozolin 4.8518220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.8020887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.8919131511
MESH:D011471 Prostatic Neoplasms Estradiol 1.8916740699
MESH:D011471 Prostatic Neoplasms methylselenic acid 1.8916205645
MESH:D011471 Prostatic Neoplasms sodium arsenite 1.8916039940
MESH:D011471 Prostatic Neoplasms Tocopherols 1.8912504091
MESH:D011471 Prostatic Neoplasms Vitamin E 1.8915084515
MESH:D011472 Prostatitis vinclozolin 4.8518629315
MESH:D011507 Proteinuria Tretinoin 3.5216636307
MESH:D019310 Pseudolymphoma Valproic Acid 4.4612752131 11422049
MESH:D011625 Pterygium Tretinoin 4.7116723453
MESH:D015427 Reperfusion Injury pirinixic acid 2.3419058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7518990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.313692021
MESH:D012208 Rhabdomyosarcoma Tretinoin 10.5816116481 16283617
MESH:D012208 Rhabdomyosarcoma Valproic Acid 10.5819155313
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.8716646077
MESH:D012559 Schizophrenia Valproic Acid 2.0615737665 19110320
MESH:D012640 Seizures Ethanol 5.979754883
MESH:D012640 Seizures Valproic Acid 5.9716876388 11738929 14763951 15475178 1511512 11044598 17978042 3137016
MESH:D012871 Skin Diseases Vitamin E 2.4218709164
MESH:D012878 Skin Neoplasms sodium arsenite 9.1918572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.1916192470
MESH:D012878 Skin Neoplasms Tretinoin 9.1916467112
MESH:D016135 Spinal Dysraphism sodium arsenite 9.3112854658
MESH:D016135 Spinal Dysraphism Valproic Acid 9.3119490988
MESH:D013226 Status Epilepticus Valproic Acid 4.4612833885
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.3917007042
MESH:D013274 Stomach Neoplasms Ethanol 3.3918456281
MESH:D013274 Stomach Neoplasms Tretinoin 3.3917261132
MESH:D013276 Stomach Ulcer Ethanol 3.4511906479 9562338 17918041 17189318 16755016 9211565
MESH:D020521 Stroke Vitamin E 3.4516517955
MESH:D013375 Substance Withdrawal Syndrome Ethanol 4.179754883
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8212697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 11.576587162 3712494 7505956 6582329 1399818
MESH:D013964 Thyroid Neoplasms arsenic trioxide 11.5719014326
MESH:D013964 Thyroid Neoplasms Tretinoin 11.5717045167 16026305
MESH:D013978 Tibial Fractures Estradiol 4.6019048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.7116051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.8815213294
MESH:D014178 Translocation, Genetic Valproic Acid 5.1517262798
MESH:D014376 Tuberculosis Tretinoin 3.1716040207
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.443119515
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 8.138074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.1311780464 20435036 12845720 12973940
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 8.1316712894 16452187 11723127 17306315
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.568888407
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 9.1511813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 9.1516129372
MESH:D014604 Uveal Neoplasms Tretinoin 4.5316752155
MESH:D014652 Vascular Diseases sodium arsenite 4.3417056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5112125929
MESH:D014820 Vitiligo Tretinoin 3.9716761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1715886252
MESH:D009396 Wilms Tumor Tretinoin 3.8916287080
Pathway ID Pathway Name
KEGG:04020 Calcium signaling pathway
KEGG:04012 ErbB signaling pathway
KEGG:04971 Gastric acid secretion
KEGG:05214 Glioma
KEGG:04912 GnRH signaling pathway
KEGG:04720 Long-term potentiation
KEGG:04916 Melanogenesis
KEGG:04722 Neurotrophin signaling pathway
KEGG:04740 Olfactory transduction
KEGG:04114 Oocyte meiosis
REACT:6900 Signaling in Immune system
REACT:13685 Synaptic Transmission
KEGG:05152 Tuberculosis
KEGG:04310 Wnt signaling pathway
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB08699 - 1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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