AutismKB 2.0

Annotation Detail for NETO2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NETO2 ( FLJ10430,FLJ14724,FLJ90456,NEOT2 )
Gene Full Name: neuropilin (NRP) and tolloid (TLL)-like 2
Band: 16q12.1
Quick LinksEntrez ID:81831; OMIM: 607974; Uniprot ID:NETO2_HUMAN; ENSEMBL ID: ENSG00000171208; HGNC ID: 14644
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of NETO2 mRNAdecreases expression 19933214
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in increased expression of NETO2 mRNAincreases expression 20406850
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of NETO2 mRNAdecreases expression 20382639
19150397
D004041 Dietary Fats Dietary Fats results in increased expression of NETO2 mRNAincreases expression 18042831
D005472 Fluorouracil NETO2 protein affects the susceptibility to Fluorouracilaffects response to substance 16217747
C041786 palm oil palm oil results in increased expression of NETO2 mRNAincreases expression 18042831
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of NETO2 mRNAdecreases expression 19933214
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of NETO2 mRNAincreases expression 19465110
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.2411752688 15322242 14514962
MESH:D000230 Adenocarcinoma Fluorouracil 2.4817638652
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.7716835633
MESH:D000740 Anemia Fluorouracil 9.5817963324 15504547 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 9.5811748828
MESH:D001161 Arteriosclerosis Dietary Fats 4.2515238619
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.3312125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.2315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.9315746008
MESH:D001943 Breast Neoplasms Dietary Fats 1.8620435547
MESH:D001943 Breast Neoplasms Fluorouracil 1.8616110121 15136595 18357371 19217205 16557594 16595493 18608205
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.8620435547
MESH:D002276 Carcinoid Tumor Fluorouracil 5.1116051944
MESH:D002277 Carcinoma Fluorouracil 8.9417121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 8.9416835633
MESH:D003528 Carcinoma, Adenoid Cystic marker/mechanism 16762588
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 3.1916705839
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 3.1917088986 16332177 17971768 16799960 18930000 17045692
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 3.1318695887
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 2.5518986760 16757204 16280240 17066447
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.5018850075 18670907 16120746
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 7.266135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.2620889678
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.4116835633
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.208697196 12621046 16354765 15668235 15340226
MESH:D003110 Colonic Neoplasms Fluorouracil 2.2717172411 17725105 17169374 16510598 17287894 15001691 18772588 16340194 17016597 17018589
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.0018288408 15148649 18949393 16303861 17255274 16331619 16391804 14970324 18448328 17401013 17594712 20501625 17016601 17454858 17094418 17695437 16282729 16524972 15289873 18802399 18383874 18509181
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.3114669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2610048152 20055451 15322242
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.3818551238
MESH:D007644 Darier Disease Fluorouracil 5.1916733453
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7217107852
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 3.9218551238 21346803
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.9220420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.9611462148
MESH:D050171 Dyslipidemias Dietary Fats 3.6518367378
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.6511000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.3518230668 16714409 15322242
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.299294722 10568697
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.7120426865
MESH:D004938 Esophageal Neoplasms Fluorouracil 4.7115173087 16337965 17638652 16481741 16785472
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.2111564622
MESH:D005234 Fatty Liver Dietary Fats 3.5219551842 17967931 18296743 19004024
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.8111858732
MESH:D005355 Fibrosis Dietary Fats 9.8418296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 9.8420067830
MESH:D005910 Glioma Fluorouracil 2.9616145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.0410696789
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.5618337622 15102660 15162350
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.4610048152 11294989
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.6211000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.2515340226 16120746 12621046
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.4915340226 8697196 16959395 16354765 18606429
MESH:D006937 Hypercholesterolemia Dietary Fats 3.8721332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.9221332399
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9918850075 18670907
MESH:D007249 Inflammation Dietary Fats 5.3420412841
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 5.3412878042 12200463
MESH:D007333 Insulin Resistance Dietary Fats 3.2718457598 11836018
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.6216580747
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 8.2716705839
MESH:D007680 Kidney Neoplasms Fluorouracil 8.2716985049
MESH:D008103 Liver Cirrhosis Dietary Fats 3.0118296743
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 1.2412878042
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 7.947678174
MESH:D008113 Liver Neoplasms Fluorouracil 7.9418383874 15113037 16603448 17045692
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 7.9416984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 6.272876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 6.2712151625
MESH:D008175 Lung Neoplasms Fluorouracil 2.4115246190
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.4111884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 5.1915086387
MESH:D009062 Mouth Neoplasms Fluorouracil 3.8416757204 18986760
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.2412213967
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.267678174 18551238
MESH:D009369 Neoplasms Fluorouracil 2.7216928823 18600527 18239605
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.5414600291
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.6116436463
MESH:D009765 Obesity Dietary Fats 2.3418674790 20132043 21332399 16723640 20518802 18457598 17217161 19632207 11836018
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.7016049721
MESH:D010190 Pancreatic Neoplasms Fluorouracil 2.7416929163 19003803 15113037 16500647
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.6912520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.8918163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.5911222880 11118676 11399792 11896295
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.3719082440 18626508
MESH:D012004 Rectal Neoplasms Fluorouracil 4.2616160472 18722050 18286688 15538739
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.1718990726
MESH:D012468 Salivary Gland Neoplasms marker/mechanism 16762588
MESH:D012640 Seizures 2,6-dinitrotoluene 2.7118551238
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.1516192470
MESH:D013274 Stomach Neoplasms Fluorouracil 2.0016424979 18567086 17522103 19015929 17498489 18396642 17172411 15786421 16951190 19084572
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.3512697716
MESH:D014062 Tongue Neoplasms Fluorouracil 4.2516280240
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.3816049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.7110091137
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 4.1416803524
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.0412125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.6915886252
MESH:D015430 Weight Gain Dietary Fats 3.9916723640
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved