AutismKB 2.0

Annotation Detail for ARID1A


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Basic Information Top
Gene Symbol:ARID1A ( B120,BAF250,BAF250a,BM029,C1orf4,P270,SMARCF1 )
Gene Full Name: AT rich interactive domain 1A (SWI-like)
Band: 1p36.11
Quick LinksEntrez ID:8289; OMIM: 603024; Uniprot ID:ARI1A_HUMAN; ENSEMBL ID: ENSG00000117713; HGNC ID: 11110
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
P00057Wnt signaling pathway
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of ARID1A mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of ARID1A mRNAaffects expression 21346803
D017638 Asbestos, Crocidolite Asbestos, Crocidolite affects the expression of ARID1A mRNAaffects expression 17331233
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ARID1A mRNAdecreases expression 20382639
19150397
20018196
D007213 Indomethacin Indomethacin results in decreased expression of ARID1A mRNAdecreases expression 16984733
D007657 Ketone Bodies Ketone Bodies results in decreased expression of ARID1A mRNAdecreases expression 16807920
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Indomethacin 2.8416537180
MESH:D000236 Adenoma Indomethacin 3.6111497255
MESH:D016301 Alveolar Bone Loss Indomethacin 5.8917225004
MESH:D000544 Alzheimer Disease Indomethacin 2.7615579461 17627676
MESH:D001014 Aortic Aneurysm Indomethacin 5.2310231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 5.2910388637
MESH:D018771 Arthralgia Indomethacin 5.692160914
MESH:D001172 Arthritis, Rheumatoid Indomethacin 2.8811248219
MESH:D001477 Bartter Syndrome Indomethacin 5.4010684365
MESH:D001929 Brain Edema Indomethacin 5.5511481608
MESH:D002545 Brain Ischemia Indomethacin 4.8812524144
MESH:D001943 Breast Neoplasms Indomethacin 2.8017401462
MESH:D002056 Burns Indomethacin 5.1210459503
MESH:D002100 Cachexia Indomethacin 5.4716537180 15141370 11239499 15625704
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 4.8816705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 4.8816705839
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 4.8816391822
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 5.1911053908
MESH:D018276 Carcinoma, Medullary Indomethacin 5.8111352223 18791128 14736730
MESH:D002292 Carcinoma, Renal Cell Indomethacin 3.5017341418
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 2.9215482327 12636206
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 7.356135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.3520889678
MESH:D002764 Cholecystitis Indomethacin 5.6911181007
MESH:D003110 Colonic Neoplasms Indomethacin 2.6315786552 11260862 15963497 15625704 15936596 15637740
MESH:D015179 Colorectal Neoplasms Indomethacin 2.3617054584 12606626 11197048 18059344
MESH:D018352 Coronavirus Infections Indomethacin 6.2417302372
MESH:D003490 Cyanosis 2,4-dinitrotoluene 12.3218551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 12.3218551238
MESH:D003967 Diarrhea Indomethacin 4.177237001 7907874
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 4.1118551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 4.1118551238 21346803
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 5.6117190690 18446180 12774134 18043480 16133044 16326151
MESH:D004381 Duodenal Ulcer Indomethacin 4.5211595431 17351913 17202747 11991626 17045617 10671773 11595415 11535926 16699067 17329845 17151854
MESH:D004487 Edema Indomethacin 3.828985016 19703484 8273558 16100529 7990266 7907874 10653021
MESH:D004715 Endometriosis Indomethacin 4.4515652904
MESH:D019446 Endotoxemia Indomethacin 4.9618509659
MESH:D004751 Enteritis Indomethacin 5.2710567023 16328016 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 5.4017980183
MESH:D004802 Eosinophilia Indomethacin 4.4711298111
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.8620426865
MESH:D004938 Esophageal Neoplasms Indomethacin 4.8611005569
MESH:D005334 Fever Indomethacin 4.4217627676 10431976 11852909
MESH:D005354 Fibrosarcoma Indomethacin 5.3610962813
MESH:D005355 Fibrosis Indomethacin 4.4917994277
MESH:D005499 Folliculitis Indomethacin 5.6911298111
MESH:D005756 Gastritis Indomethacin 5.2715046732
MESH:D005909 Glioblastoma Indomethacin 3.7512870263
MESH:D005910 Glioma Indomethacin 3.3318371953 16487511
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 4.5411849393
MESH:D006073 Gout Indomethacin 5.8111248219
MESH:D006258 Head and Neck Neoplasms Indomethacin 3.9415482327
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.9015633222
MESH:D019698 Hepatitis C, Chronic Indomethacin 5.0615135802
MESH:D006930 Hyperalgesia Indomethacin 4.0212727271
MESH:D034321 Hyperamylasemia Indomethacin 6.2417883296
MESH:D006940 Hyperemia Indomethacin 5.4712524144
MESH:D006949 Hyperlipidemias Indomethacin 4.5117546600
MESH:D007077 Ileal Diseases Indomethacin 5.5518306037 10574470
MESH:D007079 Ileitis Indomethacin 5.8110651667 16133968 10647630
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.8916133044
MESH:D007249 Inflammation Indomethacin 3.123291741 12568917 7812673
MESH:D007410 Intestinal Diseases Indomethacin 4.7415610444 17329856 18236018 15831440 17994277 11713966 10210152 11686837 11855677
MESH:D019586 Intracranial Hypertension Indomethacin 5.8915241188
MESH:D007579 Jejunal Diseases Indomethacin 5.5518306037 16133968 10574470
MESH:D007674 Kidney Diseases Indomethacin 3.4317190690
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 8.2716705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 8.2716705839
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 4.1712228301 10320625 11703811
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 4.1516572323 15631656 10785260
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 2.6718360721
MESH:D007964 Leukocytosis Indomethacin 5.8916537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 6.2417980183
MESH:D008101 Liver Abscess, Amebic Indomethacin 6.2411479899
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 2.3718194892
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.247678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.722876784 2876786 6135515
MESH:D055370 Lung Injury Asbestos, Crocidolite 4.4417365036
MESH:D008175 Lung Neoplasms Indomethacin 2.3616537180 11497255 11053908
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.2816966607 16166281 18303189
MESH:D008881 Migraine Disorders Indomethacin 3.8911903285
MESH:D009062 Mouth Neoplasms Indomethacin 4.2312636206
MESH:D009336 Necrosis 2,4-dinitrotoluene 11.9418551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 11.9418551238 7678174
MESH:D009362 Neoplasm Metastasis Indomethacin 3.2711239499 11053908 16537180
MESH:D009374 Neoplasms, Experimental Indomethacin 4.5515625704 10663608
MESH:D019636 Neurodegenerative Diseases Indomethacin 4.2112349958
MESH:D007752 Obstetric Labor, Premature Indomethacin 5.696374098
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 9.9212819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 9.9216049721
MESH:D010003 Osteoarthritis Indomethacin 3.847009135
MESH:D010146 Pain Indomethacin 3.7217440234 13679232 17627676 3291741
MESH:D010149 Pain, Postoperative Indomethacin 5.2012538197 18702446
MESH:D010195 Pancreatitis Indomethacin 4.2717883296 15028970
MESH:D010257 Paraneoplastic Syndromes Indomethacin 6.2416537180
MESH:D020734 Parkinsonian Disorders Indomethacin 4.4212349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 6.2411903285
MESH:D010437 Peptic Ulcer Indomethacin 5.6111148446
MESH:D010518 Periodontitis Indomethacin 5.4317225004
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 5.3110923243
MESH:D047928 Premature Birth Indomethacin 5.5517000239
MESH:D011507 Proteinuria Indomethacin 4.5111849393
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 3.1317365031 17322281 15814490 17975199
MESH:D012640 Seizures 2,4-dinitrotoluene 6.5618551238
MESH:D012640 Seizures 2,6-dinitrotoluene 6.5618551238
MESH:D013272 Stomach Diseases Indomethacin 4.8817160473 16280098 10486359 15038085 10215738 16184426 17207306 15472012 18209964 18545984 10192188 17638125 16113693
MESH:D013274 Stomach Neoplasms Indomethacin 2.3615609394
MESH:D013276 Stomach Ulcer Indomethacin 3.9018543354 12467913 15138204 16934674 15255614 18237397 16252198 11145282 17627676 18181030 15104355 14567935 12077510 18299717 11595415 11729361 17135157 18087811 12500499 12498302 18431645 18209962 16755016 11523592 16397915 11595431 10878458 18726076 18193104 11906479 17977527 12787963 16150113 16169175 10750652 1323529 17895592 17918041 17657623 10423059 17654042 16631530
MESH:D013964 Thyroid Neoplasms Indomethacin 3.8214736730 18791128 11352223
MESH:D014456 Ulcer Indomethacin 5.3617380554 10574470
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 5.3616049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.3616049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 13.5810091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 13.5810091137
MESH:D014839 Vomiting Indomethacin 5.2711897121
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA35960
    • Releated gene ID Related gene Name
    PA164722334MIR101-1
    PA164722335MIR101-2
    No data
    Releated drug ID Related drug Name
    PA448547beclomethasone
    PA164754818betamethasone
    PA448681budesonide
    PA164781399ciclesonide
    PA164776996desonide
    PA449247dexamethasone
    PA449661flunisolide
    PA449686fluticasone propionate
    PA452347glucocorticoids
    PA449905hydrocortisone
    PA450466methylprednisolone
    PA450541mometasone
    PA164777035paramethasone
    PA451096prednisolone
    PA451100prednisone
    PA164752251rimexolone
    PA451749triamcinolone
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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