AutismKB 2.0

Annotation Detail for CDC7


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CDC7 ( CDC7L1,HsCDC7,Hsk1,MGC117361,MGC126237,MGC126238,huCDC7 )
Gene Full Name: cell division cycle 7 homolog (S. cerevisiae)
Band: 1p22.1
Quick LinksEntrez ID:8317; OMIM: 603311; Uniprot ID:CDC7_HUMAN; ENSEMBL ID: ENSG00000097046; HGNC ID: 1745
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04110Cell cycle
Pathway IDPathway Name
Cell Cycle, Mitotic
DNA Replication
Cell Cycle Checkpoints
No data
No data
Pathway IDPathway Name
500981Activation of the pre-replicative complex
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of CDC7 mRNAincreases expression 18648102
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of CDC7 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride results in decreased expression of CDC7 proteindecreases expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of CDC7 mRNAincreases expression 17530438
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of CDC7 mRNAincreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CDC7 mRNAdecreases expression 20382639
D016572 Cyclosporine Cyclosporine results in decreased expression of CDC7 mRNAdecreases expression 20106945
D004317 Doxorubicin CDC7 protein affects the susceptibility to Doxorubicinaffects response to substance 16217747
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of CDC7 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CDC7 mRNAaffects cotreatment|increases expression 17942748
C106014 gedunin gedunin results in decreased expression of CDC7 mRNAdecreases expression 17010675
D011794 Quercetin Quercetin results in decreased expression of CDC7 mRNAdecreases expression 14715546
D013974 Thyroxine Thyroxine results in increased expression of CDC7 mRNAincreases expression 17403546
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of CDC7 mRNAdecreases expression 20106945
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CDC7 mRNAaffects cotreatment|increases expression 17942748
C496197 trans-10,cis-12-conjugated linoleic acid trans-10,cis-12-conjugated linoleic acid results in decreased expression of CDC7 mRNAdecreases expression 17951470
C050414 tripterine tripterine results in decreased expression of CDC7 mRNAdecreases expression 17010675
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.9014514962 15322242 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.6118287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0017505938
MESH:D000230 Adenocarcinoma arsenic trioxide 10.2411798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 10.2420464547 20127859
MESH:D000230 Adenocarcinoma Doxorubicin 10.2417418594
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 10.2414692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 6.653712494
MESH:D000236 Adenoma Benzo(a)pyrene 6.656695378
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.4316835633
MESH:D000419 Albuminuria Doxorubicin 4.5821441931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9711748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.2717084956
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.1219183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6815885639
MESH:D001260 Ataxia Telangiectasia Quercetin 5.0315336622
MESH:D001327 Autoimmune Diseases Quercetin 4.4519761891
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.081440618 11289319
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 9.0616206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 9.0612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7815746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.7614601052
MESH:D001932 Brain Neoplasms Doxorubicin 3.8417150277
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9620146248 17474063
MESH:D001943 Breast Neoplasms Doxorubicin 1.9619526202 15692762 15939500 17983394 15136595 17369602 15634643 16115903 18695136 18234424 16264153 15993339 17426702 16096432 15994142 18628466 16935488 18382427 16322301 16826403 16595493 15668708 15567936 11325840
MESH:D001943 Breast Neoplasms Quercetin 1.9618628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9620435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.3611589617
MESH:D002105 Cadmium Poisoning Quercetin 5.6116962696
MESH:D002276 Carcinoid Tumor Doxorubicin 4.8716051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8216835633
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 8.943581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 8.9421507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 8.9411135700 14691202 15073043 15553829 16217749
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 8.9416234567 18059187 17876044 16023760
MESH:D006528 Carcinoma, Hepatocellular Quercetin 8.9419519916 12508355
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 5.0017234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.9419014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 6.597296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 6.5916201981 1485588
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.1412490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.7220419170
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 4.726189445
MESH:D006332 Cardiomegaly Quercetin 11.6419794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 11.6418670907 18850075 16120746
MESH:D006332 Cardiomegaly Thyroxine 11.6418093424
MESH:D009202 Cardiomyopathies Doxorubicin 3.5515792986 17308081 16731534 15476868 16109756 17519947 17351982 17007740 17329180 16612575 16269455 16455267 17131338 17924179 18627295 16242529 15505089 17382496 17928571 17974986 16651473 16278810 16952015 15811867 16364871
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.9516243910 17334414
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 11.257505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 11.2520889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 11.2512371664
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1916835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 13.5119486331 9022650
MESH:D002779 Cholestasis Cyclosporine 13.5119486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.5117333356 16105132 17110522 17681005 11677210 16919318 15861022
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.118697196 15668235 15340226 12621046 16354765
MESH:D003110 Colonic Neoplasms Quercetin 2.4219056647 17191121 11134977 16640504 15741050 17148506 19440933
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.5220501625
MESH:D015179 Colorectal Neoplasms Doxorubicin 3.5218259882 18802399
MESH:D015179 Colorectal Neoplasms Quercetin 3.5218852136 18095365
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0817141729 14669216
MESH:D023903 Coronary Restenosis arsenic trioxide 4.2212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.4810525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4815322242 20055451 10048152
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.1315213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.8418759878 8156756 14531868 12868966 2524372 11906362 8970840 11298694
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.523621924 2952479
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.7519496084
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6717107852
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 6.278291058 18692083 7440962 9653073 9328219 11289319 16192314 6482804 6679447 18648102 1440618 18289764 9022650
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 6.2717416283
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.2720420201
MESH:D004362 Drug Toxicity Doxorubicin 8.1818602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 8.1811462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.4112711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9616714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.2212538720
MESH:D016889 Endometrial Neoplasms Doxorubicin 3.4717359293
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.059294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.2218037988
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 10.443581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.4420426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 10.4412903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 10.4416530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0311564622
MESH:D005234 Fatty Liver arsenic trioxide 13.2415073043
MESH:D005234 Fatty Liver Cyclosporine 13.2419224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 13.2415345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5011858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.086705139
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.6419069698
MESH:D005355 Fibrosis Cyclosporine 15.0312639820 12168785
MESH:D005355 Fibrosis Quercetin 15.0319474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 15.0320067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.3016904648
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.278708960
MESH:D005909 Glioblastoma Doxorubicin 7.4417150277
MESH:D005909 Glioblastoma Quercetin 7.4419804834
MESH:D005910 Glioma Quercetin 3.0617643826
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.077505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6610696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 3.5515692506
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.4920471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.4911294989 10048152
MESH:D006331 Heart Diseases Doxorubicin 3.5016144979 16879835 16330681 16495754 18674790 14766674 16244371 16244372 16707910 18006777 17888722 17875725 12587719
MESH:D006333 Heart Failure Doxorubicin 3.3617481944
MESH:D006394 Hemangiosarcoma Doxorubicin 3.9315692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.4715720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3611000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.556705139
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.9316120746 15340226 12621046
MESH:D006689 Hodgkin Disease Doxorubicin 3.4318501091 15147373 17606976
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.1116959395 15340226 8697196 18606429 16354765
MESH:D006943 Hyperglycemia Quercetin 4.0618262572 11834736
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.9815034207
MESH:D006973 Hypertension Cyclosporine 8.6410903974
MESH:D006973 Hypertension Quercetin 8.6418356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.6418850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8516945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5017937319
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.8712878042 12200463
MESH:D007251 Influenza, Human Quercetin 4.5716624496
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.088074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3616580747
MESH:D007627 Keloid Quercetin 5.0017086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.5015604871
MESH:D007674 Kidney Diseases Cyclosporine 10.258314463 10903974 18776723
MESH:D007674 Kidney Diseases Doxorubicin 10.2516775033 15369732 15699352
MESH:D007674 Kidney Diseases Quercetin 10.2516962696
MESH:D007676 Kidney Failure, Chronic Doxorubicin 4.1816707910
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 7.356582329
MESH:D007680 Kidney Neoplasms Cyclosporine 7.3512371664
MESH:D007938 Leukemia arsenic trioxide 6.5315070760
MESH:D007938 Leukemia Quercetin 6.5317468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.2216085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.8217077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.3616972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.4514633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.7919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1416467208 17050201 20471514 16968895 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.2312679006 9834237 16330433 17712046 17217047 11468182 15622746 12018890 17869043 15336539 19035177 16331271 16823087 15748426 19642359 12712474 16891316 19225113 19075265 15213294 17107899 16112521 16966277 11161223 17649720
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.3916882451
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.2115034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 3.5716439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 3.5712741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.5712878042
MESH:D008113 Liver Neoplasms Aflatoxin B1 14.369163691 15890375 2125692 18177683
MESH:D008113 Liver Neoplasms arsenic trioxide 14.3614682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 14.3620195826 21137059
MESH:D008113 Liver Neoplasms Quercetin 14.3618980244
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 14.3616984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 23.62598648 6587162 1399818 3712494
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 23.628603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 23.6220377131
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 23.6217085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Quercetin 23.6219519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 23.6212151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3715213294
MESH:D008175 Lung Neoplasms Aflatoxin B1 8.6114755239
MESH:D008175 Lung Neoplasms arsenic trioxide 8.6111798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 8.6120464547 20869020 17053015 18569708 18520028 20064080 6695378 18816296 20135361
MESH:D008175 Lung Neoplasms Doxorubicin 8.6117418594 6189445
MESH:D008175 Lung Neoplasms Quercetin 8.6116280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.6119555203 11884234
MESH:D008223 Lymphoma Doxorubicin 3.4816098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.8117654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.6115621674
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 3.0515458769
MESH:D008545 Melanoma Doxorubicin 2.2916827129
MESH:D008654 Mesothelioma Doxorubicin 3.0717638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.8516801185
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.5315792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.2116381670
MESH:D052016 Mucositis Doxorubicin 4.8417415656
MESH:D009101 Multiple Myeloma arsenic trioxide 3.1211468182 19417148 15949261 14977855 19549372
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.7318349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.1616105982 16882451
MESH:D009203 Myocardial Infarction Doxorubicin 6.0615857846 19429709
MESH:D009203 Myocardial Infarction Quercetin 6.0619595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0412213967
MESH:D015428 Myocardial Reperfusion Injury Quercetin 3.8119207477
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.0016624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 5.883581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 5.8818259882
MESH:D009369 Neoplasms Benzo(a)pyrene 5.1811141357
MESH:D009369 Neoplasms Quercetin 5.1815185748
MESH:D009401 Nephrosis Doxorubicin 4.8116899518 16636307
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.5017954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 9.3818481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 9.3815640375 16889571
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.2514600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.316679447
MESH:D009436 Neural Tube Defects arsenic trioxide 7.3110525206
MESH:D009447 Neuroblastoma Doxorubicin 3.2715555623
MESH:D020078 Neurogenic Inflammation Quercetin 4.3917929310
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.454026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.083988306
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.2519495926
MESH:D012516 Osteosarcoma Doxorubicin 4.1315930896
MESH:D010051 Ovarian Neoplasms arsenic trioxide 5.0416624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Quercetin 5.0419005980
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 5.4615580305
MESH:D010190 Pancreatic Neoplasms Quercetin 5.4616965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7211578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.527296757
MESH:D010235 Paraganglioma arsenic trioxide 4.1919927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3112520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.536228378
MESH:D003557 Phyllodes Tumor Doxorubicin 5.2217983394
MESH:D010997 Pleural Neoplasms Doxorubicin 5.2217638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5918163543
MESH:D011230 Precancerous Conditions Cyclosporine 9.1912371664
MESH:D011230 Precancerous Conditions Quercetin 9.1919056647
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2411896295 11399792 11118676 11222880
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.0919131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.0917292933
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.0915897917 18437689 16868541 16729912 16888761 15749863
MESH:D011471 Prostatic Neoplasms Quercetin 2.0914715546 17292933
MESH:D011537 Pruritus Ethinyl Estradiol 3.3616919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.2416882103
MESH:D051437 Renal Insufficiency Doxorubicin 4.2617922066
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8718990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.393692021
MESH:D012509 Sarcoma Doxorubicin 4.0116767912 17203757 17710206 15625365 18313854 15675481
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 10.4016646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 10.4016326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.8417846226
MESH:D012554 Schistosomiasis japonica Quercetin 5.6116862918
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 9.5110029692 19755658
MESH:D012878 Skin Neoplasms Doxorubicin 9.5115692506
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.5116192470
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.6117203757 16767912 15625365
MESH:D013088 Spermatocele Ethinyl Estradiol 4.0016709447
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.3717007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.3720155912 2093021
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 12.5912697716
MESH:D013959 Thyroid Diseases Thyroxine 12.5919910387
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 12.143712494 6582329 6587162 7505956 1399818
MESH:D013964 Thyroid Neoplasms arsenic trioxide 12.1419014326
MESH:D013964 Thyroid Neoplasms Doxorubicin 12.1416010429 17909728
MESH:D016171 Torsades de Pointes arsenic trioxide 4.0115213294
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 15.938074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 15.9311780464 20435036 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 15.9317053015
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 15.9317653716
MESH:D001749 Urinary Bladder Neoplasms Quercetin 15.9316720314
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3314692618
MESH:D014605 Uveitis Cyclosporine 4.051336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6612125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5715869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.2617638931 17678736 17334414 16364871
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3115886252
MESH:D014985 Xerophthalmia Cyclosporine 4.5017120751
Pathway ID Pathway Name
KEGG:04110 Cell cycle
REACT:1538 Cell Cycle Checkpoints
REACT:152 Cell Cycle, Mitotic
REACT:383 DNA Replication
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved