Annotation Detail for KATNAL2
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D004041 |
Dietary Fats |
Dietary Fats results in decreased expression of KATNAL2 mRNA | decreases expression | 18042831
|
| C041786 |
palm oil |
palm oil results in decreased expression of KATNAL2 mRNA | decreases expression | 18042831
|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of KATNAL2 mRNA | affects binding|decreases expression|increases activity | 19710929
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.64 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.22 | 16434500 |
| MESH:D001161 |
Arteriosclerosis |
|
Dietary Fats |
4.54 | 15238619 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.63 | 19483382 |
| MESH:D001943 |
Breast Neoplasms |
|
Dietary Fats |
2.24 | 20435547 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.15 | 19176532 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.59 | 18249437 |
| MESH:D050171 |
Dyslipidemias |
|
Dietary Fats |
3.76 | 18367378 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.96 | 12083418 |
| MESH:D005234 |
Fatty Liver |
|
Dietary Fats |
9.35 | 17967931 18296743 19004024 19551842 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
9.35 | 19236843 20131406 |
| MESH:D005355 |
Fibrosis |
|
Dietary Fats |
4.17 | 18296743 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.78 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.64 | 18467677 16221962 19772884 19176532 |
| MESH:D006937 |
Hypercholesterolemia |
|
Dietary Fats |
4.08 | 21332399 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.63 | 20558911 |
| MESH:D006949 |
Hyperlipidemias |
|
Dietary Fats |
4.14 | 21332399 |
| MESH:D007249 |
Inflammation |
|
Dietary Fats |
2.62 | 20412841 |
| MESH:D007333 |
Insulin Resistance |
|
Dietary Fats |
8.15 | 11836018 18457598 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
8.15 | 16306350 |
| MESH:D008103 |
Liver Cirrhosis |
|
Dietary Fats |
3.09 | 18296743 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.94 | 20007298 15890375 16377806 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.16 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.29 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.29 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.12 | 17405874 |
| MESH:D009765 |
Obesity |
|
Dietary Fats |
4.71 | 17217161 11836018 21332399 20518802 18674790 16723640 18457598 19632207 20132043 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
4.71 | 20558911 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.56 | 19058328 |
| MESH:D015430 |
Weight Gain |
|
Dietary Fats |
4.15 | 16723640 |
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