AutismKB 2.0

Annotation Detail for PLVAP


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Basic Information Top
Gene Symbol:PLVAP ( FELS,PV-1,PV1,gp68 )
Gene Full Name: plasmalemma vesicle associated protein
Band: 19p13.11
Quick LinksEntrez ID:83483; OMIM: 607647; Uniprot ID:PLVAP_HUMAN; ENSEMBL ID: ENSG00000130300; HGNC ID: 13635
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of PLVAP mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PLVAP mRNAaffects expression 16483693
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of PLVAP mRNA]affects reaction|decreases expression 19482888
D010634 Phenobarbital Phenobarbital results in decreased expression of PLVAP mRNAdecreases expression 19482888
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PLVAP mRNAaffects binding|increases activity|increases expression 19710929
D012643 Selenium Selenium results in increased expression of PLVAP mRNAincreases expression 19244175
C024746 tobacco tar tobacco tar results in decreased expression of PLVAP mRNAdecreases expression 19559774
C025643 vinclozolin vinclozolin affects the expression of PLVAP mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 3.836195326
MESH:D000138 Acidosis Ammonium Chloride 3.9518287403
MESH:D055371 Acute Lung Injury pirinixic acid 3.4218653653
MESH:D018248 Adenoma, Liver Cell Phenobarbital 11.4817620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 11.4816434500
MESH:D000799 Angioedema Acetaminophen 4.2910982225
MESH:D001008 Anxiety Disorders vinclozolin 3.8619015723
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.4319483382
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.983084413
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 2.9820007298 17173139 20935162 6705139 1701930
MESH:D002386 Cataract Acetaminophen 2.7310977129
MESH:D002471 Cell Transformation, Neoplastic tobacco tar 4.1319559774
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.614080065
MESH:D002779 Cholestasis pirinixic acid 3.0319176532
MESH:D003092 Colitis Selenium 4.1417936198
MESH:D003456 Cryptorchidism vinclozolin 4.6714966744
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5318249437
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.012444490 19416960 19420014 10915739 16393943 11421492 16485898 16781746 17562736 17522070 16177239 14725611 14986274 10663392 12392966 11529661 16081117 15968718 11834606 12705907 19085960 12958197 19370779 19739265 19923254 14550746 16109766 11287661 18713872 12540782 12594235 17906064 19164858 11461765 15619225 18071297 10774834 16227642 11743745 12153990 11739529
MESH:D056486 Drug-Induced Liver Injury Selenium 4.0115131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.5419426721
MESH:D004421 Dystonia Phenobarbital 4.311851702
MESH:D004487 Edema pirinixic acid 2.7612083418
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.473659116
MESH:D004828 Epilepsies, Partial Phenobarbital 4.313922381 11558140
MESH:D004827 Epilepsy Phenobarbital 3.0120417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.796401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.617750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.413659116
MESH:D005234 Fatty Liver pirinixic acid 3.0419236843 20131406
MESH:D005756 Gastritis Acetaminophen 4.1216983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.3316973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.7416417039
MESH:D006333 Heart Failure pirinixic acid 7.4820558911
MESH:D006333 Heart Failure Selenium 7.4817162251
MESH:D006529 Hepatomegaly Phenobarbital 9.7016109766
MESH:D006529 Hepatomegaly pirinixic acid 9.7018467677 16221962 19772884 19176532
MESH:D006930 Hyperalgesia Acetaminophen 2.9216870215
MESH:D006943 Hyperglycemia pirinixic acid 3.4520558911
MESH:D007248 Infertility, Male vinclozolin 3.2116467254
MESH:D007251 Influenza, Human Selenium 4.6416624496
MESH:D007333 Insulin Resistance pirinixic acid 2.8016306350
MESH:D007674 Kidney Diseases Acetaminophen 2.3412587719 15629191
MESH:D007676 Kidney Failure, Chronic Selenium 4.1716518626
MESH:D007984 Leydig Cell Tumor vinclozolin 5.1316417039
MESH:D008103 Liver Cirrhosis Phenobarbital 3.0321047994
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008107 Liver Diseases Acetaminophen 4.1312969438 19460945 16611625 19784758 12587719 19014921 16610002 11587558
MESH:D008107 Liver Diseases Phenobarbital 4.1319363144
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5017185352 16871587
MESH:D008113 Liver Neoplasms Phenobarbital 4.7621047994 19812893 19482888 19073162 15975961 8742319
MESH:D008113 Liver Neoplasms pirinixic acid 4.7616377806 20007298 15890375
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 2.861399818 6150874 17172636 2563599 18308698
MESH:D008325 Mammary Neoplasms, Experimental Selenium 2.9215318939
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9319513568
MESH:D008654 Mesothelioma Selenium 2.8815107826
MESH:D009135 Muscular Diseases pirinixic acid 3.8616239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2419151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1616411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.8717484760
MESH:D009369 Neoplasms pirinixic acid 2.0617405874
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1018514411
MESH:D009765 Obesity pirinixic acid 1.8620558911
MESH:D010018 Osteomalacia Phenobarbital 4.7617016548
MESH:D010146 Pain Acetaminophen 2.6216870215
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.5716965848
MESH:D010954 Plasmacytoma Selenium 5.3315087411
MESH:D011230 Precancerous Conditions Phenobarbital 3.872563599
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 4.2919015723 18220299 18042343
MESH:D011469 Prostatic Diseases vinclozolin 5.3318220299
MESH:D011472 Prostatitis vinclozolin 5.3318629315
MESH:D019310 Pseudolymphoma Phenobarbital 4.9412752131
MESH:D015427 Reperfusion Injury pirinixic acid 2.5019058328
MESH:D012640 Seizures Phenobarbital 2.8711442880 4039156 3137016 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 5.226407741
MESH:D013964 Thyroid Neoplasms Phenobarbital 3.261399818
MESH:D014581 Urticaria Acetaminophen 3.2810982225
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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