AutismKB 2.0

Annotation Detail for MAD1L1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MAD1L1 ( MAD1,PIG9,TP53I9,TXBP181 )
Gene Full Name: MAD1 mitotic arrest deficient-like 1 (yeast)
Band: 7p22.3
Quick LinksEntrez ID:8379; OMIM: 602686; Uniprot ID:MD1L1_HUMAN; ENSEMBL ID: ENSG00000002822; HGNC ID: 6762
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04914Progesterone-mediated oocyte maturation
hsa04110Cell cycle
Pathway IDPathway Name
Cell Cycle, Mitotic
DNA Replication
Cell Cycle Checkpoints
Pathway IDPathway Name
200130C-MYB transcription factor network
No data
Pathway IDPathway Name
500325Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Related Diseases/Disorders Top
No data
No data
Desease Name
Carcinoma, Hepatocellular
CANCER
Neoplasm Recurrence, Local
Liver Neoplasms
No data
Desease Name
Lymphoma, somatic
Prostate cancer, somatic
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C014024 2,4,5,2',4',5'-hexachlorobiphenyl 2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of MAD1L1 mRNAincreases expression 20005886
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of MAD1L1 proteinaffects expression 20106945
D001374 Azacitidine Azacitidine results in decreased expression of MAD1L1 mRNAdecreases expression 19194470
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of MAD1L1 mRNAdecreases expression 20106945
20064835
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of MAD1L1 mRNAdecreases expression 20382639
19150397
C006780 bisphenol A bisphenol A results in increased expression of MAD1L1 mRNAincreases expression 16474171
D002330 Carmustine Carmustine results in decreased expression of MAD1L1 mRNAdecreases expression 15980968
D004958 Estradiol Estradiol results in increased expression of MAD1L1 mRNAincreases expression 16474171
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MAD1L1 mRNAaffects cotreatment|increases expression 17942748
D019833 Genistein Genistein results in increased expression of MAD1L1 mRNAincreases expression 16474171
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of MAD1L1 mRNAincreases expression 20713471
D015741 Metribolone Metribolone results in decreased expression of MAD1L1 proteindecreases expression 17152098
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of MAD1L1 mRNAaffects binding|decreases expression|increases activity 19710929
D011078 Polychlorinated Biphenyls Polychlorinated Biphenyls analog results in increased expression of MAD1L1 mRNAincreases expression 16474171
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MAD1L1 mRNAaffects cotreatment|increases expression 17942748
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased expression of MAD1L1 mRNAincreases expression 19031421
D014212 Tretinoin Tretinoin results in decreased expression of MAD1L1 mRNAdecreases expression 16140955
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.8411752688 15322242 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9417505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.1018653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 10.1220127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 10.1211473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 10.1214692618
MESH:D000230 Adenocarcinoma Genistein 10.1211473722
MESH:D000236 Adenoma Benzo(a)pyrene 6.836695378
MESH:D000236 Adenoma Methylcholanthrene 6.8310545420 6695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.8716434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.8716835633
MESH:D000505 Alopecia Tretinoin 3.6015955085
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9311748828
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.0619183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.1615885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.1616412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2616292516
MESH:D001249 Asthma Tretinoin 2.3416456186
MESH:D050197 Atherosclerosis Methylcholanthrene 3.4411922910
MESH:D001471 Barrett Esophagus Tretinoin 4.3916935849
MESH:D001778 Blood Coagulation Disorders pirinixic acid 15.1719483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 15.1712125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 15.1716197459 16206674
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7515746008
MESH:D001862 Bone Resorption bisphenol A 3.8411985600
MESH:D001932 Brain Neoplasms Carmustine 4.3716187019
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 3.7617474063 20146248
MESH:D001943 Breast Neoplasms bisphenol A 3.7617123778
MESH:D001943 Breast Neoplasms Estradiol 3.7617289903 18497071 12948864 19861407 14630087 17018787 16675129 17261762
MESH:D001943 Breast Neoplasms Genistein 3.7616873071 16541309 17200150
MESH:D001943 Breast Neoplasms Methylcholanthrene 3.7617474063
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.7620435547
MESH:D001943 Breast Neoplasms Tretinoin 3.7616443354 16166294 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.5816813970
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.4516111702
MESH:D002277 Carcinoma Methylcholanthrene 8.2810545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 8.2816835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.1616168501
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 6.5721507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Estradiol 6.5716924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 6.5716924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 6.571917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.9817123778
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 7.5620419170
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 7.5618922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 7.5616096774 16051514
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3516120746 18850075 18670907
MESH:D002318 Cardiovascular Diseases Genistein 3.2916332659
MESH:D002386 Cataract Tretinoin 3.0817460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 11.1820889678
MESH:D002471 Cell Transformation, Neoplastic Estradiol 11.1818566989
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 11.1816192471
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.5816129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1416835633
MESH:D002779 Cholestasis Ethinyl Estradiol 7.6916919318 17681005 17110522 16105132 15861022 11677210 17333356
MESH:D002779 Cholestasis pirinixic acid 7.6919176532
MESH:D002822 Choriocarcinoma Tretinoin 5.1616461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.748697196 12621046 15340226 15668235 16354765
MESH:D002972 Cleft Palate Tretinoin 5.749407595
MESH:D003092 Colitis Tretinoin 3.6917035595
MESH:D003110 Colonic Neoplasms Genistein 2.2817182828
MESH:D015179 Colorectal Neoplasms Azacitidine 3.1319934284
MESH:D015179 Colorectal Neoplasms Polychlorinated Biphenyls 3.1315531428
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0414669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4410048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.449211117 16925845 8800419 10589399 9125849 17551590 9142499 14991402 9224671 9664655
MESH:D003704 Dementia Polychlorinated Biphenyls 4.6816140633
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4118249437
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 4.3116647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.3117107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.3919279558
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 1.5320420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7411462148
MESH:D004487 Edema pirinixic acid 11.3612083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 11.3611000095 12711302
MESH:D004487 Edema Tetradecanoylphorbol Acetate 11.369599246 15177302 8273558 16716910 7812673 11698051 8113982
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.9515322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 11.9518230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.1712538720
MESH:D004714 Endometrial Hyperplasia Genistein 4.5816402032
MESH:D016889 Endometrial Neoplasms Estradiol 12.3911473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Genistein 12.3911473722
MESH:D016889 Endometrial Neoplasms Tretinoin 12.3916569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.0010568697 9294722
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.3320426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.3316530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.7811564622
MESH:D005124 Eye Abnormalities Tretinoin 8.789664655 16938888
MESH:D005234 Fatty Liver Ethinyl Estradiol 7.4815345470
MESH:D005234 Fatty Liver pirinixic acid 7.4819236843 20131406
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4411858732
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.9310962813 14633661
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.5720067830
MESH:D005355 Fibrosis Tretinoin 8.5717994277
MESH:D005909 Glioblastoma Carmustine 11.9316187019
MESH:D005909 Glioblastoma Genistein 11.9316598420
MESH:D005909 Glioblastoma Tretinoin 11.9317312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5910696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.1716096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.1616084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 11.0320471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 11.0311294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 11.0314991402 9664655
MESH:D006333 Heart Failure pirinixic acid 2.5220558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3211000095
MESH:D006529 Hepatomegaly pirinixic acid 8.2219176532 18467677 16221962 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.2215340226 16120746 12621046
MESH:D006558 Herpes Genitalis Estradiol 5.0315709030
MESH:D019584 Hot Flashes Estradiol 3.7517088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.058697196 16959395 16354765 15340226 18606429
MESH:D006930 Hyperalgesia Tretinoin 3.1916870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.5516778211
MESH:D006943 Hyperglycemia pirinixic acid 3.1620558911
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9018670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8016945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4412013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4717937319
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 5.1212200463 12878042
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 5.1211698051 7812673 7562506 8273558 15177302
MESH:D007333 Insulin Resistance bisphenol A 12.2416393666
MESH:D007333 Insulin Resistance Estradiol 12.2416393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 12.2416306350
MESH:D007410 Intestinal Diseases Tretinoin 3.7517994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.8716580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.8715992940 17551590
MESH:D007674 Kidney Diseases Estradiol 2.5715618244
MESH:D007680 Kidney Neoplasms Estradiol 2.9615610895
MESH:D007938 Leukemia Azacitidine 10.5619148494
MESH:D007938 Leukemia Genistein 10.5617468513 18980019
MESH:D007938 Leukemia Tretinoin 10.5617143497
MESH:D007951 Leukemia, Myeloid Azacitidine 9.7319077051
MESH:D007951 Leukemia, Myeloid Tretinoin 9.7316932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute Azacitidine 4.1818720364 17596541
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 4.1816294345 19850784 17596541
MESH:D054429 Leukemia, Myelomonocytic, Juvenile Azacitidine 5.1719299654
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.1416823087 19225113 17294898 17506722 17339181 16331271 19075265 16788101 19642359 17301526 17649720 16935935 17712046 17217047 9834237 16766008 17107899 17368321 16891316 12679006 19035177 15748426 17361223 19029980 16140955
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.299224671
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.7014716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 6.7017823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.7015474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.7012878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 6.7016248980 18397230
MESH:D008113 Liver Neoplasms 2,4,5,2',4',5'-hexachlorobiphenyl 14.1716835634 18644402
MESH:D008113 Liver Neoplasms Aflatoxin B1 14.179163691 18177683 2125692 15890375
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 14.1721137059 20195826
MESH:D008113 Liver Neoplasms pirinixic acid 14.1716377806 20007298 15890375
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 14.1716984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 14.098603461
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 14.091399818 598648
MESH:D008114 Liver Neoplasms, Experimental Polychlorinated Biphenyls 14.091423854
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 14.0912151625
MESH:D008175 Lung Neoplasms Aflatoxin B1 8.5414755239
MESH:D008175 Lung Neoplasms Azacitidine 8.5421224363
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 8.5420464547 17053015 18816296 18520028 18569708 20064080 20869020 6695378 20135361
MESH:D008175 Lung Neoplasms Methylcholanthrene 8.5415390079 10545420 7750092 21163286 20970405 17909032 9230183 20512841 1399818 16337739 16271038 6695378 11893704
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.5411884234 19555203
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 8.5411807781
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 10.0011807958 17203775 16891317 11408345
MESH:D008325 Mammary Neoplasms, Experimental Genistein 10.0014578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 10.008985016
MESH:D020149 Manganese Poisoning Estradiol 4.4819453300
MESH:D008527 Medulloblastoma Tretinoin 2.7817453147
MESH:D008545 Melanoma Carmustine 3.6412393984
MESH:D008545 Melanoma Tretinoin 3.6416752155
MESH:D008591 Meningomyelocele Tretinoin 4.4116940565
MESH:D009006 Monosomy Azacitidine 6.0819299654
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.1716381670
MESH:D009101 Multiple Myeloma Azacitidine 3.9518443271 19549372
MESH:D009135 Muscular Diseases pirinixic acid 3.4916239165
MESH:D009190 Myelodysplastic Syndromes Azacitidine 7.6718720364 17611569 19805378 17596541
MESH:D009190 Myelodysplastic Syndromes Tretinoin 7.6717596541
MESH:D009203 Myocardial Infarction Genistein 5.6517141266
MESH:D009203 Myocardial Infarction pirinixic acid 5.6519151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0012213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 14.0816810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 14.0817141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 14.0816411023
MESH:D009369 Neoplasms 2,4,5,2',4',5'-hexachlorobiphenyl 11.828820588
MESH:D009369 Neoplasms Benzo(a)pyrene 11.8211141357
MESH:D009369 Neoplasms pirinixic acid 11.8217405874
MESH:D009369 Neoplasms Tretinoin 11.8216946489 16594593
MESH:D009389 Neovascularization, Pathologic Estradiol 3.7217289903
MESH:D009421 Nervous System Malformations bisphenol A 30.6011399458 16427766
MESH:D009421 Nervous System Malformations Estradiol 30.6011399458 16427766
MESH:D009421 Nervous System Malformations Genistein 30.6016427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 30.6014600291
MESH:D009421 Nervous System Malformations Tretinoin 30.609125849
MESH:D009436 Neural Tube Defects Tretinoin 3.049142499
MESH:D009765 Obesity pirinixic acid 1.8120558911
MESH:D010024 Osteoporosis Genistein 3.2419401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 4.0716169203
MESH:D010049 Ovarian Diseases bisphenol A 4.9811985600
MESH:D010051 Ovarian Neoplasms Estradiol 7.8619401270
MESH:D010051 Ovarian Neoplasms Genistein 7.8619005980
MESH:D010051 Ovarian Neoplasms Tretinoin 7.8616936753
MESH:D010146 Pain Tretinoin 2.8816870215
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 5.4915976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 5.4915976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6711578682
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 4.288330346 12065085 18404319 18922899
MESH:D010300 Parkinson Disease Polychlorinated Biphenyls 3.3816702228
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2512520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5418163543
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 9.4810548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.4811118676 11222880 11896295 11399792
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 10.4920887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 10.4920887781
MESH:D011471 Prostatic Neoplasms marker/mechanism
MESH:D011471 Prostatic Neoplasms Azacitidine 1.9018324645
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.9017292933
MESH:D011471 Prostatic Neoplasms bisphenol A 1.9016740699
MESH:D011471 Prostatic Neoplasms Estradiol 1.9016740699
MESH:D011471 Prostatic Neoplasms Genistein 1.9016925846 15256057 15378649
MESH:D011471 Prostatic Neoplasms Polychlorinated Biphenyls 1.9015721890
MESH:D011507 Proteinuria Tretinoin 3.5916636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.3015861022 16919318
MESH:D011625 Pterygium Tretinoin 4.7816723453
MESH:D011629 Puberty, Precocious bisphenol A 4.7810548101
MESH:D015427 Reperfusion Injury pirinixic acid 2.3819058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8218990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.0816283617 16116481
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 13.5010029692 19755658
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 13.5016192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 13.5018404319 8985016 8330346 11807781 12065085
MESH:D012878 Skin Neoplasms Tretinoin 13.5016467112
MESH:D013088 Spermatocele Ethinyl Estradiol 3.9416709447
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.342093021 20155912
MESH:D013274 Stomach Neoplasms Tretinoin 2.3417261132
MESH:D019966 Substance-Related Disorders bisphenol A 3.9716045194 16684133
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1315669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9012697716
MESH:D013964 Thyroid Neoplasms Tretinoin 3.0116026305 17045167
MESH:D013978 Tibial Fractures Estradiol 4.6919048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.7716051514
MESH:D014376 Tuberculosis Tretinoin 3.2116040207
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.1717053015
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.6616129372
MESH:D014591 Uterine Diseases bisphenol A 5.0114652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2814692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.6116752155
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5912125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5214671159 15869587
MESH:D014820 Vitiligo Tretinoin 4.0416761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2515886252
MESH:D009396 Wilms Tumor Tretinoin 3.9516287080
Pathway ID Pathway Name
KEGG:04110 Cell cycle
REACT:1538 Cell Cycle Checkpoints
REACT:152 Cell Cycle, Mitotic
REACT:383 DNA Replication
KEGG:04914 Progesterone-mediated oocyte maturation
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA372
    • No data
    Releated disease ID Related disease Name
    PA443560Breast Neoplasms
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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