Annotation Detail for HMCN1
Basic Information
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| Desease Name |
|---|
| Macular degeneration, age-related, 1 |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D001151 |
Arsenic |
Arsenic results in decreased expression of HMCN1 mRNA | decreases expression | 19654921
|
| D002117 |
Calcitriol |
Calcitriol results in increased expression of HMCN1 mRNA | increases expression | 16002434
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D018246 |
Adrenocortical Adenoma |
|
Arsenic |
6.28 | 17306315 |
| MESH:D020261 |
Arsenic Poisoning |
|
Arsenic |
2.97 | 16835338 12569548 18414634 16251483 |
| MESH:D050197 |
Atherosclerosis |
|
Arsenic |
3.51 | 12928151 19371607 |
| MESH:D001943 |
Breast Neoplasms |
|
Calcitriol |
2.56 | 11237771 |
| MESH:D002280 |
Carcinoma, Basal Cell |
|
Arsenic |
3.83 | 15504454 17687452 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Arsenic |
2.32 | 16507464 17306315 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Arsenic |
5.29 | 17687452 15504454 18922899 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Calcitriol |
5.29 | 11237771 |
| MESH:D002295 |
Carcinoma, Transitional Cell |
|
Arsenic |
4.58 | 18640142 |
| MESH:D002318 |
Cardiovascular Diseases |
|
Arsenic |
3.77 | 15738583 17938729 19152805 |
| MESH:D002340 |
Carotid Artery Diseases |
|
Arsenic |
4.78 | 18022660 16973168 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Calcitriol |
4.61 | 15138306 |
| MESH:D005534 |
Foot Diseases |
|
Arsenic |
6.63 | 6392382 |
| MESH:D017488 |
Hyperkeratosis, Epidermolytic |
|
Arsenic |
4.96 | 17050553 |
| MESH:D006973 |
Hypertension |
|
Arsenic |
3.01 | 16076760 9931084 11953799 |
| MESH:D006987 |
Hypesthesia |
|
Arsenic |
6.63 | 16093927 |
| MESH:D007642 |
Keratosis |
|
Arsenic |
5.88 | 16930632 12749816 |
| MESH:D015473 |
Leukemia, Promyelocytic, Acute |
|
Arsenic |
3.85 | 17339181 |
| MESH:D008107 |
Liver Diseases |
|
Arsenic |
2.63 | 11134558 |
| MESH:D008113 |
Liver Neoplasms |
|
Arsenic |
2.82 | 16368122 |
| MESH:D008175 |
Lung Neoplasms |
|
Arsenic |
2.21 | 19168569 17306315 17976673 |
| MESH:D008268 |
Macular Degeneration |
marker/mechanism |
|
| |
| MESH:D017202 |
Myocardial Ischemia |
|
Arsenic |
4.39 | 15371236 |
| MESH:D009436 |
Neural Tube Defects |
|
Arsenic |
3.75 | 16620997 |
| MESH:D020078 |
Neurogenic Inflammation |
|
Arsenic |
4.98 | 17056641 |
| MESH:D010051 |
Ovarian Neoplasms |
|
Arsenic |
2.86 | 17306315 |
| MESH:D010523 |
Peripheral Nervous System Diseases |
|
Arsenic |
4.85 | 16093927 |
| MESH:D016491 |
Peripheral Vascular Diseases |
|
Arsenic |
5.88 | 15371236 6392382 16905509 |
| MESH:D011470 |
Prostatic Hyperplasia |
|
Calcitriol |
5.67 | 15572423 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Arsenic |
3.42 | 16140617 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Calcitriol |
3.42 | 16289102 18247401 16644109 15754350 12479363 |
| MESH:D011507 |
Proteinuria |
|
Arsenic |
4.61 | 21343184 |
| MESH:D012871 |
Skin Diseases |
|
Arsenic |
2.84 | 17548696 19834688 17453740 16759981 6392382 17938729 16353154 18709164 17050553 15952646 16702368 |
| MESH:D012878 |
Skin Neoplasms |
|
Arsenic |
3.19 | 17029826 17050553 17976673 16251483 19538983 15504454 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
Arsenic |
2.96 | 11144890 18640142 19322015 15987713 17976673 19429237 17306315 |
| MESH:D014652 |
Vascular Diseases |
|
Arsenic |
5.62 | 17056641 |
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