Annotation Detail for PRSS27
Basic Information Top
| Gene Symbol: | PRSS27 ( CAPH2,MPN ) |
|---|---|
| Gene Full Name: | protease, serine 27 |
| Band: | 16p13.3 |
| Quick Links | Entrez ID:83886; OMIM: 608018; Uniprot ID:PRS27_HUMAN; ENSEMBL ID: ENSG00000172382; HGNC ID: 15475 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of PRSS27 mRNA | affects expression | 17562736 |
| C014707 | nitrosobenzylmethylamine | nitrosobenzylmethylamine results in increased expression of PRSS27 mRNA | increases expression | 17616710 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 4.91 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.83 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 19164858 11421492 19085960 17522070 12153990 19739265 12594235 16109766 16485898 14725611 19420014 12705907 12958197 18713872 16227642 11739529 11529661 15968718 15619225 11743745 19923254 11461765 16177239 19416960 14986274 11287661 12540782 10915739 16393943 16081117 2444490 16781746 10663392 18071297 19370779 17906064 17562736 10774834 12392966 14550746 11834606 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 5.17 | 19426721 | |
| MESH:D004938 | Esophageal Neoplasms | nitrosobenzylmethylamine | 2.86 | 15264214 15547721 15878914 16805852 15547733 15150132 16510608 16704527 15623463 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.74 | 16983495 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.11 | 16870215 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.44 | 12587719 15629191 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 19460945 16611625 12587719 12969438 19014921 16610002 11587558 19784758 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.74 | 16871587 17185352 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.33 | 19513568 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.31 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.82 | 16870215 | |
| MESH:D013274 | Stomach Neoplasms | nitrosobenzylmethylamine | 2.33 | 17575124 12958204 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.58 | 10982225 |
| No data |