AutismKB 2.0

Annotation Detail for RASSF4


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Basic Information Top
Gene Symbol:RASSF4 ( AD037,MGC44914 )
Gene Full Name: Ras association (RalGDS/AF-6) domain family member 4
Band: 10q11.21
Quick LinksEntrez ID:83937; OMIM: 610559; Uniprot ID:RASF4_HUMAN; ENSEMBL ID: ENSG00000107551; HGNC ID: 20793
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016572 Cyclosporine Cyclosporine results in decreased expression of RASSF4 mRNAdecreases expression 20106945
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of RASSF4 mRNAincreases expression 17005392
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000686 Amyloidosis Diethylstilbestrol 5.1615469931
MESH:D001943 Breast Neoplasms Diethylstilbestrol 2.5815324884 17129689
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 2.2815948411 16924424
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.8512371664
MESH:D002779 Cholestasis Cyclosporine 3.2819486331
MESH:D003456 Cryptorchidism Diethylstilbestrol 5.2312952375 16002989
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 5.5816402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 3.7616804899 15700306
MESH:D005234 Fatty Liver Cyclosporine 3.4019224547
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.9216534752 16513791 16611131 16002989 15751030
MESH:D005355 Fibrosis Cyclosporine 3.9012639820 12168785
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 5.8316452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 5.118708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.3115720958
MESH:D006965 Hyperplasia Diethylstilbestrol 5.2014722030 12960047
MESH:D006973 Hypertension Cyclosporine 2.2410903974
MESH:D007021 Hypospadias Diethylstilbestrol 5.3416002989
MESH:D007246 Infertility Diethylstilbestrol 5.0315036965
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.5115604871
MESH:D007674 Kidney Diseases Cyclosporine 2.588314463 10903974 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 8.9312371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 8.9315003126 16762066 14681315
MESH:D007859 Learning Disorders Diethylstilbestrol 4.8217184923
MESH:D008113 Liver Neoplasms Diethylstilbestrol 2.7716712894 15890375
MESH:D008181 Lupus Nephritis Diethylstilbestrol 6.0415166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.8115700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 6.5916002989
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.8616801185
MESH:D009369 Neoplasms Diethylstilbestrol 2.9615313581
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.5117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.7519348381 18481113
MESH:D009421 Nervous System Malformations Diethylstilbestrol 4.8111399458
MESH:D010900 Pituitary Diseases Diethylstilbestrol 6.2414722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 5.4316977796 15687265
MESH:D011230 Precancerous Conditions Cyclosporine 3.6912371664
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 5.0017184923
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 3.4915046698 17136230 15846301
MESH:D011565 Psoriasis Cyclosporine 2.3516882103
MESH:D013088 Spermatocele Diethylstilbestrol 5.7816002989 16709447
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 2.9216452187 16712894 17306315
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 4.5416175088
MESH:D014591 Uterine Diseases Diethylstilbestrol 6.2414652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 4.7415809267 16690809
MESH:D014605 Uveitis Cyclosporine 5.051336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 5.2016513791 16002989
MESH:D014985 Xerophthalmia Cyclosporine 5.5117120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018