AutismKB 2.0

Annotation Detail for PLA2G6


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Basic Information Top
Gene Symbol:PLA2G6 ( CaI-PLA2,GVI,INAD1,IPLA2-VIA,NBIA2A,NBIA2B,PARK14,PLA2,PNPLA9,iPLA2 )
Gene Full Name: phospholipase A2, group VI (cytosolic, calcium-independent)
Band: 22q13.1
Quick LinksEntrez ID:8398; OMIM: 603604; Uniprot ID:PA2G6_HUMAN; ENSEMBL ID: ENSG00000184381; HGNC ID: 9039
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
LIPASYN-PWYphospholipases
Pathway IDPathway Name
hsa00565Ether lipid metabolism
hsa00564Glycerophospholipid metabolism
hsa04270Vascular smooth muscle contraction
hsa04912GnRH signaling pathway
hsa04010MAPK signaling pathway
hsa00590Arachidonic acid metabolism
hsa05145Toxoplasmosis
hsa04730Long-term depression
hsa04972Pancreatic secretion
hsa00592alpha-Linolenic acid metabolism
hsa01100Metabolic pathways
hsa00591Linoleic acid metabolism
hsa04370VEGF signaling pathway
hsa04664Fc epsilon RI signaling pathway
hsa04666Fc gamma R-mediated phagocytosis
No data
No data
No data
No data
Related Diseases/Disorders Top
Desease IDDesease Name
Nervous system diseases
Neurodegenerative diseases
H00057Parkinson's disease
No data
Desease Name
Cutaneous nevi
Desease Name
Cutaneous nevi
Desease Name
Neurodegeneration with brain iron accumulation 2B
Karak syndrome
Infantile neuroaxonal dystrophy 1
Dystonia-parkinsonism, adult-onset
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C447028 2,2',4,6-tetrachlorobiphenyl PLA2G6 protein promotes the reaction [2,2',4,6-tetrachlorobiphenyl results in increased secretion of Arachidonic Acid]increases reaction|increases secretion 16120751
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of PLA2G6 mRNAaffects expression 21346803
C068314 6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one 6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one results in decreased activity of PLA2G6 proteindecreases activity 16436530
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PLA2G6 mRNAaffects expression 16483693
D016718 Arachidonic Acid PLA2G6 protein promotes the reaction [2,2',4,6-tetrachlorobiphenyl results in increased secretion of Arachidonic Acid]increases reaction|increases secretion 16120751
D001241 Aspirin Aspirin results in increased expression of PLA2G6 mRNAincreases expression 11906190
D001554 Benzene Benzene results in decreased expression of PLA2G6 mRNAdecreases expression 17905399
D002118 Calcium Calcium deficiency results in increased activity of PLA2G6 proteinincreases activity 17885217
D004041 Dietary Fats Dietary Fats results in decreased expression of PLA2G6 mRNAdecreases expression 18042831
C057416 KT 5720 KT 5720 inhibits the reaction [UCN protein results in decreased expression of PLA2G6 protein]decreases expression|decreases reaction 17885217
C041786 palm oil palm oil results in decreased expression of PLA2G6 mRNAdecreases expression 18042831
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased expression of PLA2G6 mRNAincreases expression 17681415
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of PLA2G6 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of PLA2G6 mRNAincreases expression 19482888
D010656 Phenylephrine PLA2G6 protein affects the susceptibility to Phenylephrineaffects response to substance 17885217
C006253 pirinixic acid pirinixic acid results in increased expression of PLA2G6 mRNAincreases expression 20059764
17426115
18301758
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of PLA2G6 mRNA]increases expression|increases reaction 20059764
C059514 resveratrol resveratrol results in increased expression of PLA2G6 mRNAincreases expression 15767336
D014284 Triiodothyronine Triiodothyronine results in increased expression of PLA2G6 mRNAincreases expression 15953391
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of PLA2G6 mRNAdecreases expression 19465110
D019284 Thapsigargin PLA2G6 protein affects the susceptibility to Thapsigarginaffects response to substance 17885217
D019284 Thapsigargin Thapsigargin results in increased activity of PLA2G6 proteinincreases activity 17885217
D019284 Thapsigargin UCN protein inhibits the reaction [Thapsigargin results in increased activity of PLA2G6 protein]decreases reaction|increases activity 17885217
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 8.096195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.0911752688 14514962 15322242
MESH:D000138 Acidosis Ammonium Chloride 3.5018287403
MESH:D058186 Acute Kidney Injury resveratrol 3.7916538975
MESH:D055371 Acute Lung Injury pirinixic acid 3.0518653653
MESH:D000236 Adenoma resveratrol 3.2815688382
MESH:D018248 Adenoma, Liver Cell Phenobarbital 16.9417620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.9416434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.9416835633
MESH:D000544 Alzheimer Disease resveratrol 2.5516162502 16183991
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8911748828
MESH:D000741 Anemia, Aplastic Benzene 4.3214761424 11369114 17661222
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 4.0517460149
MESH:D001161 Arteriosclerosis Dietary Fats 3.8215238619
MESH:D001169 Arthritis, Experimental resveratrol 3.4617115116
MESH:D055963 Asthma, Aspirin-Induced Aspirin 4.6412372130 20485159
MESH:D050197 Atherosclerosis resveratrol 3.2316873680 17967414
MESH:D001321 Autistic Disorder Arachidonic Acid 3.0318582451
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.5619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.5612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7215746008
MESH:D001855 Bone Marrow Diseases Benzene 5.1716183116
MESH:D001919 Bradycardia Phenylephrine 4.4815306635
MESH:D002545 Brain Ischemia resveratrol 4.2217600658
MESH:D001932 Brain Neoplasms Aspirin 4.3515481559
MESH:D001943 Breast Neoplasms Aspirin 2.3415161893
MESH:D001943 Breast Neoplasms Benzene 2.3417162533 11921183
MESH:D001943 Breast Neoplasms Dietary Fats 2.3420435547
MESH:D001943 Breast Neoplasms resveratrol 2.3417534123 16393696 17651959
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.3420435547
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7416835633
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 4.6016705839
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 4.601701930 20007298 17173139 6705139 20935162
MESH:D006528 Carcinoma, Hepatocellular resveratrol 4.6016227395 19321006
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.5316675471
MESH:D002294 Carcinoma, Squamous Cell resveratrol 2.7016227395
MESH:D006332 Cardiomegaly Phenylephrine 6.7615728586 17287366 17124262 11754973 11179087 16170337
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.7616120746 18670907 18850075
MESH:D002318 Cardiovascular Diseases resveratrol 3.4315458977
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 2.726135515
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.194080065
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1016835633
MESH:D002779 Cholestasis pirinixic acid 2.7719176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0815668235 15340226 12621046 8697196 16354765
MESH:D003092 Colitis resveratrol 4.0616474422
MESH:D003110 Colonic Neoplasms Aspirin 4.1512411196
MESH:D003110 Colonic Neoplasms resveratrol 4.1516338953
MESH:D015179 Colorectal Neoplasms Aspirin 2.9417047198
MESH:D015179 Colorectal Neoplasms resveratrol 2.9416550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0017141729 14669216
MESH:D003327 Coronary Disease resveratrol 3.7116507316
MESH:D019465 Craniofacial Abnormalities Benzene 2.6515643154
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.6520055451 15322242 10048152
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.9518551238
MESH:D003872 Dermatitis Benzene 4.7015902427
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3918249437
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.7116873680
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6517107852
MESH:D003928 Diabetic Nephropathies resveratrol 3.9016286809
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 3.6321346803 18551238
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.6320420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7111462148
MESH:D050171 Dyslipidemias Dietary Fats 3.4018367378
MESH:D004421 Dystonia Phenobarbital 3.941851702
MESH:D004487 Edema Arachidonic Acid 26.299831321 15177302 9599246 7990266 16716910 11698051
MESH:D004487 Edema Aspirin 26.2917259670
MESH:D004487 Edema perfluorooctanoic acid 26.2917259670 12083418
MESH:D004487 Edema pirinixic acid 26.2912083418
MESH:D004487 Edema resveratrol 26.298985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 26.2912711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8516714409 18230668 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 3.9617872969
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.969294722 10568697
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.7817923197
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.043659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.8211558140 3922381
MESH:D004827 Epilepsy Phenobarbital 2.8620417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.486401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.197750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.963659116
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9611564622
MESH:D005234 Fatty Liver Dietary Fats 7.5017967931 19551842 18296743 19004024
MESH:D005234 Fatty Liver pirinixic acid 7.5019236843 20131406
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3911858732
MESH:D005334 Fever Arachidonic Acid 4.6011852909
MESH:D005355 Fibrosis Dietary Fats 8.4118296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.4120067830
MESH:D005909 Glioblastoma Aspirin 3.9112870263
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5410696789
MESH:D006261 Headache Aspirin 4.9015240983
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3011294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.5020558911
MESH:D006402 Hematologic Diseases Benzene 4.5916183116
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2711000095
MESH:D006529 Hepatomegaly perfluorooctanoic acid 20.183609246
MESH:D006529 Hepatomegaly Phenobarbital 20.1816109766
MESH:D006529 Hepatomegaly pirinixic acid 20.1816221962 18467677 19772884 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 20.1815340226 16120746 12621046
MESH:D006561 Herpes Simplex resveratrol 4.1216876885
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.998697196 15340226 16959395 18606429 16354765
MESH:D012001 Hyperacusis Aspirin 5.7115240983
MESH:D006930 Hyperalgesia perfluorooctanoic acid 3.8012083418
MESH:D006937 Hypercholesterolemia Dietary Fats 9.0121332399
MESH:D006937 Hypercholesterolemia resveratrol 9.0117188708
MESH:D006943 Hyperglycemia pirinixic acid 3.1220558911
MESH:D006949 Hyperlipidemias Dietary Fats 9.0821332399
MESH:D006949 Hyperlipidemias resveratrol 9.0816873680
MESH:D006973 Hypertension Benzene 8.6017940673
MESH:D006973 Hypertension Phenylephrine 8.608949925 12717712
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.6018670907 18850075
MESH:D006984 Hypertrophy Phenylephrine 4.4918502941 12791704
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.2417488730
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.5817600658
MESH:D007249 Inflammation Arachidonic Acid 15.5417371808 15177302 9831321
MESH:D007249 Inflammation Dietary Fats 15.5420412841
MESH:D007249 Inflammation perfluorooctanoic acid 15.5412083418
MESH:D007249 Inflammation resveratrol 15.5416366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 15.5412878042 12200463
MESH:D007251 Influenza, Human resveratrol 4.4916624496
MESH:D007333 Insulin Resistance Dietary Fats 7.1018457598 11836018
MESH:D007333 Insulin Resistance pirinixic acid 7.1016306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2716580747
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 2.9216705839
MESH:D007683 Kidney Tubular Necrosis, Acute Calcium 4.9916316344
MESH:D007938 Leukemia Benzene 3.3615935818 14694614 18335105 17119257
MESH:D007951 Leukemia, Myeloid Benzene 4.2617506065
MESH:D015470 Leukemia, Myeloid, Acute Benzene 2.6919478238
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.5316087638
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 5.178812269
MESH:D008103 Liver Cirrhosis Dietary Fats 6.5418296743
MESH:D008103 Liver Cirrhosis Phenobarbital 6.5421047994
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.1115474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.1112878042
MESH:D008107 Liver Diseases Phenobarbital 2.1519363144
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 17.677678174
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 17.6718709148 14757943
MESH:D008113 Liver Neoplasms Phenobarbital 17.678742319 15975961 19073162 19482888 19812893 21047994
MESH:D008113 Liver Neoplasms pirinixic acid 17.6720007298 16377806 15890375
MESH:D008113 Liver Neoplasms resveratrol 17.6719812893 19073162 19321006 20405173
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.6716984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 13.802876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental Benzene 13.8012562636
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 13.802563599 18308698 1399818 17172636 6150874
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.8012151625
MESH:D017563 Lung Diseases, Interstitial Benzene 4.7514698565
MESH:D008175 Lung Neoplasms Benzene 2.4812562636
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.4819555203 11884234
MESH:D008223 Lymphoma Benzene 3.6917119257 17584886
MESH:D016393 Lymphoma, B-Cell resveratrol 4.2417088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.8114749477
MESH:D015674 Mammary Neoplasms, Animal Benzene 10.0512562636
MESH:D015674 Mammary Neoplasms, Animal resveratrol 10.0515688416
MESH:D008325 Mammary Neoplasms, Experimental Benzene 6.2811921183
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 6.288985016 11606380
MESH:D008545 Melanoma resveratrol 2.3617992120
MESH:D008659 Metabolic Diseases resveratrol 4.3117112576
MESH:D008881 Migraine Disorders Aspirin 4.0215240983
MESH:D009101 Multiple Myeloma Benzene 7.4717119195
MESH:D009101 Multiple Myeloma resveratrol 7.4714749477 16490592 16267019 17164350 17935668 17049120
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.8117962980
MESH:D009135 Muscular Diseases pirinixic acid 3.4416239165
MESH:D009203 Myocardial Infarction Aspirin 9.4312692751
MESH:D009203 Myocardial Infarction pirinixic acid 9.4319151258
MESH:D009203 Myocardial Infarction resveratrol 9.4316525036 17125593 17188708 17015251 16317513 16456233
MESH:D017202 Myocardial Ischemia resveratrol 8.8317125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.8312213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8916411023
MESH:D009205 Myocarditis resveratrol 4.7017322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.4117484760
MESH:D009325 Nausea Aspirin 5.1615240983
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.807678174 18551238
MESH:D009369 Neoplasms pirinixic acid 1.9217405874
MESH:D009374 Neoplasms, Experimental resveratrol 3.948985016
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.1514600291
MESH:D009436 Neural Tube Defects Benzene 3.6315643154
OMIM:256600 NEURODEGENERATION WITH BRAIN IRON ACCUMULATION 2A marker/mechanism
OMIM:610217 NEURODEGENERATION WITH BRAIN IRON ACCUMULATION 2B marker/mechanism
MESH:D019636 Neurodegenerative Diseases resveratrol 3.7517652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.3417929310
MESH:D009506 Nevus marker/mechanism 19578365
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.899802331
MESH:D009765 Obesity Dietary Fats 4.3816723640 21332399 18457598 11836018 20518802 17217161 19632207 20132043 18674790
MESH:D009765 Obesity pirinixic acid 4.3820558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.9616049721
MESH:D009784 Occupational Diseases Benzene 8.9616737584 17119257 15576619 15612468 17178637 15727169 15913788 15935809 17479406
MESH:D010003 Osteoarthritis Aspirin 4.027009135
MESH:D010018 Osteomalacia Phenobarbital 4.3017016548
MESH:D010024 Osteoporosis Calcium 3.7417882678
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.1917513867
MESH:D010051 Ovarian Neoplasms Benzene 2.9512562636
MESH:D010146 Pain Aspirin 3.806995502 6363464
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.4716965848
OMIM:612953 PARKINSON DISEASE 14, AUTOSOMAL RECESSIVE marker/mechanism
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1912520081
MESH:D010438 Peptic Ulcer Hemorrhage Aspirin 5.4811156591
MESH:D020795 Photophobia Aspirin 5.7115240983
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4918163543
MESH:D011230 Precancerous Conditions Phenobarbital 3.562563599
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 16.0017132714
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 16.0016679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 16.0011222880 11118676 11399792 11896295
MESH:D011471 Prostatic Neoplasms resveratrol 3.6617804756 17718901 16731767 17675339 17636462 15767336
MESH:D019310 Pseudolymphoma Phenobarbital 4.4412752131
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.5316325855
MESH:D015427 Reperfusion Injury pirinixic acid 6.4619058328
MESH:D015427 Reperfusion Injury resveratrol 6.4616317513 16314181 17520802 17058453 15827377
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7718990726
MESH:D012220 Rhinitis Aspirin 4.3112372130
MESH:D012640 Seizures 2,6-dinitrotoluene 5.7718551238
MESH:D012640 Seizures Phenobarbital 5.773137016 11442880 4039156 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.766407741
MESH:D012852 Sinusitis Phenylephrine 4.647327846
MESH:D012851 Sinus Thrombosis, Intracranial Aspirin 5.2012269725
MESH:D012878 Skin Neoplasms resveratrol 5.6115837718 8985016
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.6116192470
MESH:D013274 Stomach Neoplasms Benzene 2.4212562636
MESH:D020521 Stroke Aspirin 4.3216403987
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.4216321402
MESH:D013927 Thrombosis Aspirin 4.4617672075
MESH:D013953 Thymus Neoplasms Benzene 4.8910850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8512697716
MESH:D013964 Thyroid Neoplasms Phenobarbital 3.001399818
MESH:D014062 Tongue Neoplasms resveratrol 4.1516227395
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.2616049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.2610091137
MESH:D014581 Urticaria Aspirin 4.3810982225 20485159
MESH:D002583 Uterine Cervical Neoplasms resveratrol 4.0417473185
MESH:D014594 Uterine Neoplasms Benzene 9.6712562636
MESH:D014594 Uterine Neoplasms resveratrol 9.6717044934
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5412125929
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.2417488730
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1915886252
MESH:D015430 Weight Gain Dietary Fats 3.6816723640
Pathway ID Pathway Name
KEGG:00592 alpha-Linolenic acid metabolism
KEGG:00590 Arachidonic acid metabolism
KEGG:00565 Ether lipid metabolism
KEGG:04975 Fat digestion and absorption
KEGG:04664 Fc epsilon RI signaling pathway
KEGG:04666 Fc gamma R-mediated phagocytosis
KEGG:04724 Glutamatergic synapse
KEGG:00564 Glycerophospholipid metabolism
KEGG:04912 GnRH signaling pathway
KEGG:00591 Linoleic acid metabolism
KEGG:04730 Long-term depression
KEGG:04010 MAPK signaling pathway
KEGG:01100 Metabolic pathways
KEGG:04972 Pancreatic secretion
KEGG:05145 Toxoplasmosis
KEGG:04270 Vascular smooth muscle contraction
KEGG:04370 VEGF signaling pathway
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB01103 antagonist Quinacrine Antineoplastic Agents;Enzyme Inhibitors;Antiprotozoals;Antimalarials;Anticestodal Agents;Antinematodal Agents;Antihelmintics
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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