AutismKB 2.0

Annotation Detail for SPNS1


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Basic Information Top
Gene Symbol:SPNS1 ( FLJ38358,HSpin1,LAT,PP2030,SPIN1,SPINL,nrs )
Gene Full Name: spinster homolog 1 (Drosophila)
Band: 16p11.2
Quick LinksEntrez ID:83985; OMIM: 612583; Uniprot ID:SPNS1_HUMAN; ENSEMBL ID: ENSG00000169682; HGNC ID: 30621
Relate to Another Database: SFARIGene; denovo-db
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of SPNS1 mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 5.2610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8610977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6919164858 11743745 16485898 17906064 15619225 12153990 17522070 12540782 12392966 16781746 12594235 12705907 10774834 19416960 11421492 15968718 19420014 19085960 2444490 11739529 17562736 18713872 10663392 18071297 19923254 16177239 19370779 16081117 16393943 14725611 14986274 10915739 14550746 19739265 11529661 11287661 11461765 16109766 11834606 12958197 16227642
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.5119426721
MESH:D005756 Gastritis Acetaminophen 5.0916983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1516870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4712587719 15629191
MESH:D008107 Liver Diseases Acetaminophen 1.7216611625 19014921 19784758 11587558 16610002 12587719 12969438 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.8116871587 17185352
MESH:D008546 Melanoma, Experimental Acetaminophen 4.4719513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3618514411
MESH:D010146 Pain Acetaminophen 2.8716870215
MESH:D014581 Urticaria Acetaminophen 3.6710982225
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018