AutismKB 2.0

Annotation Detail for CASP7


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Basic Information Top
Gene Symbol:CASP7 ( CMH-1,ICE-LAP3,MCH3 )
Gene Full Name: caspase 7, apoptosis-related cysteine peptidase
Band: 10q25.3
Quick LinksEntrez ID:840; OMIM: 601761; Uniprot ID:CASP7_HUMAN; ENSEMBL ID: ENSG00000165806; HGNC ID: 1508
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05010Alzheimer's disease
hsa04210Apoptosis
Pathway IDPathway Name
Apoptosis
Pathway IDPathway Name
200027E2F transcription factor network
200133HIV-1 Nef: Negative effector of Fas and TNF-alpha
200148Caspase cascade in apoptosis
Pathway IDPathway Name
P00020FAS signaling pathway
P00006Apoptosis signaling pathway
Pathway IDPathway Name
500267Activation of caspases through apoptosome-mediated cleavage
500270Apoptotic cleavage of cellular proteins
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1770Melanoma
1803Periodontitis
1841Stomach cancer
2239Lymphoma
Desease Name
diabetes, type 1
CHEMDEPENDENCY
IMMUNE
smoking cessation
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Acrolein results in increased activity of CASP7 protein]decreases reaction|increases activity 17196791
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased activity of CASP7 proteinincreases activity 16487511
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of CASP7 mRNAaffects expression 21346803
C526437 2-methoxy-3-O-sulfamoyl-17-cyanomethylestra-1,3,5(10)-triene 2-methoxy-3-O-sulfamoyl-17-cyanomethylestra-1,3,5(10)-triene results in increased activity of CASP7 proteinincreases activity 19846905
C526438 2-methoxyestradiol-3,17-O,O-bis(sulfamate) 2-methoxyestradiol-3,17-O,O-bis(sulfamate) results in increased activity of CASP7 proteinincreases activity 19846905
D000082 Acetaminophen Acetaminophen affects the expression of CASP7 mRNAaffects expression 17562736
C099158 acetyl-aspartyl-glutamyl-valyl-aspartal acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Mustard Gas results in increased cleavage of CASP7 protein]decreases reaction|increases cleavage 12482751
D000171 Acrolein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Acrolein results in increased activity of CASP7 protein]decreases reaction|increases activity 17196791
D000171 Acrolein Acrolein results in increased activity of CASP7 proteinincreases activity 17196791
17320762
15843039
D000171 Acrolein Acrolein results in increased cleavage of CASP7 proteinincreases cleavage 15843039
D000171 Acrolein anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Acrolein results in increased activity of CASP7 protein]decreases reaction|increases activity 17196791
D000171 Acrolein PD 98059 inhibits the reaction [Acrolein results in increased activity of CASP7 protein]decreases reaction|increases activity 17196791
D000171 Acrolein SB 203580 inhibits the reaction [Acrolein results in increased activity of CASP7 protein]decreases reaction|increases activity 17196791
D000171 Acrolein U 0126 inhibits the reaction [Acrolein results in increased activity of CASP7 protein]decreases reaction|increases activity 17196791
D000171 Acrolein wortmannin inhibits the reaction [Acrolein results in increased activity of CASP7 protein]decreases reaction|increases activity 17196791
D000171 Acrolein Acrolein results in increased activity of CASP7 proteinincreases activity 19596284
C430898 AGN 194204 [AGN 194204 co-treated with IGFBP3 protein] results in increased activity of CASP7 proteinaffects cotreatment|increases activity 16000583
C430898 AGN 194204 AGN 194204 results in increased activity of CASP7 proteinincreases activity 16000583
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CASP7 mRNAaffects expression 16483693
D000643 Ammonium Chloride Ammonium Chloride results in increased expression of CASP7 proteinincreases expression 16483693
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Acrolein results in increased activity of CASP7 protein]decreases reaction|increases activity 17196791
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Copper results in increased activity of CASP7 protein]decreases reaction|increases activity 16672322
D047310 Apigenin Apigenin results in increased cleavage of CASP7 proteinincreases cleavage 15486995
C006632 arsenic trioxide arsenic trioxide results in increased cleavage of CASP7 proteinincreases cleavage 19695276
C006632 arsenic trioxide arsenic trioxide results in increased cleavage of and results in increased activity of CASP7 proteinincreases activity|increases cleavage 15688020
C006632 arsenic trioxide Tretinoin promotes the reaction [arsenic trioxide results in increased cleavage of CASP7 protein]increases cleavage|increases reaction 15688020
C015001 arsenite arsenite results in increased activity of CASP7 proteinincreases activity 18316066
C517975 AZD 6244 AZD 6244 results in increased cleavage of CASP7 proteinincreases cleavage 17876044
C517975 AZD 6244 Doxorubicin promotes the reaction [AZD 6244 results in increased cleavage of CASP7 protein]increases cleavage|increases reaction 17876044
C001758 bendamustine bendamustine results in increased activity of CASP7 proteinincreases activity 12948851
C001758 bendamustine Cladribine promotes the reaction [bendamustine results in increased activity of CASP7 protein]increases activity|increases reaction 12948851
C403754 benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Etoposide results in increased activity of CASP7 protein]decreases reaction|increases activity 18056177
C400082 bortezomib bortezomib results in increased cleavage of and results in increased activity of CASP7 proteinincreases activity|increases cleavage 16024631
D002087 Butyrates Butyrates results in increased activity of CASP7 proteinincreases activity 15213223
D002087 Butyrates GSN protein inhibits the reaction [Butyrates results in increased activity of CASP7 protein]decreases reaction|increases activity 15213223
D002104 Cadmium Cadmium results in increased activity of CASP7 proteinincreases activity 16478757
D019256 Cadmium Chloride Cadmium Chloride results in increased activity of CASP7 proteinincreases activity 16478757
C111238 carboxycinnamic acid bishydroxamide carboxycinnamic acid bishydroxamide results in increased cleavage of CASP7 proteinincreases cleavage 15897598
D017338 Cladribine Cladribine promotes the reaction [bendamustine results in increased activity of CASP7 protein]increases activity|increases reaction 12948851
D017338 Cladribine Cladribine results in increased activity of CASP7 proteinincreases activity 12948851
D003300 Copper anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Copper results in increased activity of CASP7 protein]decreases reaction|increases activity 16672322
D003300 Copper Copper results in increased activity of CASP7 proteinincreases activity 16672322
D003300 Copper quinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [Copper results in increased activity of CASP7 protein]decreases reaction|increases activity 16672322
D003300 Copper SB 203580 inhibits the reaction [Copper results in increased activity of CASP7 protein]decreases reaction|increases activity 16672322
D003300 Copper U 0126 inhibits the reaction [Copper results in increased activity of CASP7 protein]decreases reaction|increases activity 16672322
D003474 Curcumin Curcumin results in decreased expression of CASP7 mRNAdecreases expression 16101141
D003474 Curcumin Curcumin results in increased cleavage of and results in increased activity of CASP7 proteinincreases activity|increases cleavage 16023083
D003513 Cycloheximide Cycloheximide inhibits the reaction [Tretinoin results in increased expression of CASP7 mRNA]decreases reaction|increases expression 16166294
D016572 Cyclosporine Cyclosporine results in increased expression of CASP7 mRNAincreases expression 20106945
D003609 Dactinomycin Dactinomycin results in decreased expression of CASP7 mRNAdecreases expression 16001973
D003634 DDT DDT results in increased activity of CASP7 proteinincreases activity 15603917
D003634 DDT SB 203580 inhibits the reaction [DDT results in increased activity of CASP7 protein]decreases reaction|increases activity 15603917
C014347 decitabine [decitabine affects the methylation of CASP7 gene] which affects the expression of CASP7 proteinaffects expression|affects methylation 18649362
C014347 decitabine [decitabine co-treated with vorinostat] affects the expression of CASP7 mRNAaffects cotreatment|affects expression 17330099
C107676 deguelin deguelin metabolite results in increased expression of CASP7 protein modified formincreases expression 19139008
C107676 deguelin deguelin results in increased expression of CASP7 protein modified formincreases expression 19139008
D004052 Diethylnitrosamine CLOCK protein promotes the reaction [Diethylnitrosamine results in increased activity of CASP7 protein]increases activity|increases reaction 21167249
D004052 Diethylnitrosamine Diethylnitrosamine results in increased activity of CASP7 proteinincreases activity 21167249
D004221 Disulfiram Disulfiram results in increased activity of CASP7 proteinincreases activity 17026967
D004317 Doxorubicin Doxorubicin affects the activity of CASP7 proteinaffects activity 15870702
D004317 Doxorubicin [Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased activity of CASP7 proteinaffects cotreatment|increases activity 16168113
D004317 Doxorubicin Doxorubicin inhibits the reaction [Thapsigargin results in increased activity of and results in increased cleavage of CASP7 protein]decreases reaction|increases activity|increases cleavage 16298333
D004317 Doxorubicin Doxorubicin results in increased activity of and results in increased cleavage of CASP7 proteinincreases activity|increases cleavage 16298333
D004317 Doxorubicin Doxorubicin results in increased activity of CASP7 proteinincreases activity 19106633
D004317 Doxorubicin Doxorubicin results in increased cleavage of and results in increased activity of CASP7 proteinincreases activity|increases cleavage 16024631
D004317 Doxorubicin Doxorubicin results in increased cleavage of CASP7 proteinincreases cleavage 17653088
D004317 Doxorubicin Doxorubicin results in increased expression of CASP7 mRNAincreases expression 16705698
16001973
D004317 Doxorubicin TNFSF10 protein promotes the reaction [Doxorubicin results in increased activity of CASP7 protein]increases activity|increases reaction 19106633
D004317 Doxorubicin Doxorubicin promotes the reaction [AZD 6244 results in increased cleavage of CASP7 protein]increases cleavage|increases reaction 17876044
D004317 Doxorubicin PARP1 gene mutant form promotes the reaction [Doxorubicin results in increased activity of CASP7 protein]increases activity|increases reaction 15861398
D004317 Doxorubicin [Verapamil results in decreased expression of ABCB1] promotes the reaction [Doxorubicin results in increased activity of CASP7 protein]decreases expression|increases activity|increases reaction 15861398
D004958 Estradiol Estradiol affects the expression of CASP7 mRNAaffects expression 14699072
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CASP7 mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of CASP7 mRNAincreases expression 17557909
D017308 Etodolac Etodolac results in increased activity of CASP7 proteinincreases activity 16046235
D005047 Etoposide benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Etoposide results in increased activity of CASP7 protein]decreases reaction|increases activity 18056177
D005047 Etoposide Etoposide results in increased activity of CASP7 proteinincreases activity 20299546
18056177
D005047 Etoposide [STAT1 protein results in increased activity of CASP7 protein] which results in increased susceptibility to Etoposideincreases activity|increases response to substance 18649362
D005047 Etoposide Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased activity of CASP7 protein]decreases reaction|increases activity 20299546
D005445 Flunitrazepam CYP3A4 protein affects the reaction [Flunitrazepam results in increased activity of CASP7 protein]affects reaction|increases activity 19005028
D005472 Fluorouracil [Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased activity of CASP7 proteinaffects cotreatment|increases activity 16168113
C071834 glycidamide glycidamide results in decreased expression of CASP7 mRNAdecreases expression 17822822
D006072 Gossypol Gossypol results in increased activity of CASP7 proteinincreases activity 19825521
D006072 Gossypol [zoledronic acid co-treated with Gossypol] results in increased activity of CASP7 proteinaffects cotreatment|increases activity 19825521
D007530 Isoflurane Isoflurane results in increased expression of CASP7 mRNAincreases expression 16978161
C510621 KCC 009 KCC 009 results in increased cleavage of CASP7 proteinincreases cleavage 16170020
C097284 manganese(III)-tetrakis(4-benzoic acid)porphyrin manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[XCT790 results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP7 protein]decreases reaction|increases abundance|increases activity 19464277
C008493 methylselenic acid HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]decreases reaction|increases cleavage 16204082
C008493 methylselenic acid methylselenic acid inhibits the reaction [CASP7 protein binds to HSPA5 protein]affects binding|decreases reaction 16204082
C008493 methylselenic acid methylselenic acid results in increased cleavage of CASP7 proteinincreases cleavage 16204082
D008942 Mitoxantrone Mitoxantrone results in increased activity of CASP7 proteinincreases activity 12948851
D009151 Mustard Gas acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Mustard Gas results in increased cleavage of CASP7 protein]decreases reaction|increases cleavage 12482751
D009151 Mustard Gas CALM1 protein promotes the reaction [Mustard Gas results in increased cleavage of and results in increased activity of CASP7 protein]increases activity|increases cleavage|increases reaction 16935404
D009151 Mustard Gas FADD protein affects the reaction [Mustard Gas results in increased cleavage of CASP7 protein]affects reaction|increases cleavage 12482751
D009151 Mustard Gas Mustard Gas promotes the reaction [CASP3 protein results in increased cleavage of CASP7 protein]increases cleavage|increases reaction 12482751
D009151 Mustard Gas Mustard Gas results in increased activity of CASP7 proteinincreases activity 12482751
D009151 Mustard Gas Mustard Gas results in increased cleavage of and results in increased activity of CASP7 proteinincreases activity|increases cleavage 16935404
D009151 Mustard Gas Mustard Gas results in increased expression of CASP7 mRNAincreases expression 15674843
C002714 nimetazepam CYP3A4 protein affects the reaction [nimetazepam results in increased activity of CASP7 protein]affects reaction|increases activity 19005028
D009567 Nitrazepam CYP3A4 protein affects the reaction [Nitrazepam results in increased activity of CASP7 protein]affects reaction|increases activity 19005028
D009599 Nitroprusside Nitroprusside results in increased expression of CASP7 mRNAincreases expression 15708893
D017239 Paclitaxel [Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased activity of CASP7 proteinaffects cotreatment|increases activity 16168113
D017239 Paclitaxel [resveratrol co-treated with Paclitaxel] results in increased cleavage of and results in increased activity of CASP7 proteinaffects cotreatment|increases activity|increases cleavage 14749477
D010269 Paraquat Paraquat results in increased activity of CASP7 proteinincreases activity 17324951
C093973 PD 98059 PD 98059 inhibits the reaction [Acrolein results in increased activity of CASP7 protein]decreases reaction|increases activity 17196791
D010424 Pentobarbital Pentobarbital results in increased expression of CASP7 mRNAincreases expression 16978161
D028321 Plant Preparations Plant Preparations affects the expression of CASP7 mRNAaffects expression 16046712
C031280 pyrazole pyrazole results in decreased expression of CASP7 mRNAdecreases expression 17945193
D011794 Quercetin Quercetin results in increased cleavage of CASP7 proteinincreases cleavage 18787224
D011794 Quercetin Quercetin results in increased expression of CASP7 proteinincreases expression 14767529
C468548 quinoline-val-asp(OMe)-CH2-OPH quinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [Copper results in increased activity of CASP7 protein]decreases reaction|increases activity 16672322
D020849 Raloxifene Raloxifene affects the expression of CASP7 mRNAaffects expression 14699072
D020849 Raloxifene [Raloxifene co-treated with ESR2 protein] results in decreased expression of CASP7 mRNAaffects cotreatment|decreases expression 19059307
D017382 Reactive Oxygen Species manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[XCT790 results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP7 protein]decreases reaction|increases abundance|increases activity 19464277
D017382 Reactive Oxygen Species [XCT790 results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP7 proteinincreases abundance|increases activity 19464277
C059514 resveratrol [resveratrol co-treated with Paclitaxel] results in increased cleavage of and results in increased activity of CASP7 proteinaffects cotreatment|increases activity|increases cleavage 14749477
C059514 resveratrol resveratrol promotes the reaction [TNFSF10 protein results in increased cleavage of CASP7 protein]increases cleavage|increases reaction 17823925
D012402 Rotenone MT1B protein inhibits the reaction [Rotenone results in increased activity of CASP7 protein]decreases reaction|increases activity 16402917
D012402 Rotenone MT2A protein inhibits the reaction [Rotenone results in increased activity of CASP7 protein]decreases reaction|increases activity 16402917
D012402 Rotenone Rotenone results in increased activity of CASP7 proteinincreases activity 16402917
C093642 SB 203580 SB 203580 inhibits the reaction [Acrolein results in increased activity of CASP7 protein]decreases reaction|increases activity 17196791
C093642 SB 203580 SB 203580 inhibits the reaction [DDT results in increased activity of CASP7 protein]decreases reaction|increases activity 15603917
C093642 SB 203580 SB 203580 inhibits the reaction [Copper results in increased activity of CASP7 protein]decreases reaction|increases activity 16672322
C115461 SC 560 SC 560 results in increased activity of CASP7 proteinincreases activity 16391822
D022641 Shiga Toxin 2 Shiga Toxin 2 results in increased activity of CASP7 proteinincreases activity 12826277
D022641 Shiga Toxin 2 Terbutaline inhibits the reaction [Shiga Toxin 2 results in increased activity of CASP7 protein]decreases reaction|increases activity 12826277
D022641 Shiga Toxin 2 [Terbutaline results in increased activity of ADRB2 protein] inhibits the reaction [Shiga Toxin 2 results in increased activity of CASP7 protein]decreases reaction|increases activity 12826277
C017947 sodium arsenite sodium arsenite results in decreased expression of CASP7 mRNAdecreases expression 12760830
D018038 Sodium Selenite Sodium Selenite affects the expression of CASP7 mRNAaffects expression 16705456
D019311 Staurosporine Staurosporine results in increased activity of CASP7 proteinincreases activity 16402917
D013311 Streptozocin Streptozocin results in increased expression of CASP7 proteinincreases expression 15976052
C016766 sulforafan sulforafan results in increased activity of CASP7 proteinincreases activity 17942926
D013629 Tamoxifen Tamoxifen affects the expression of CASP7 mRNAaffects expression 14699072
D013629 Tamoxifen [Tamoxifen co-treated with ESR2 protein] results in decreased expression of CASP7 mRNAaffects cotreatment|decreases expression 19059307
C508490 TDP 521252 TDP 521252 results in increased activity of CASP7 proteinincreases activity 16432175
D013726 Terbutaline Terbutaline inhibits the reaction [Shiga Toxin 2 results in increased activity of CASP7 protein]decreases reaction|increases activity 12826277
D013726 Terbutaline [Terbutaline results in increased activity of ADRB2 protein] inhibits the reaction [Shiga Toxin 2 results in increased activity of CASP7 protein]decreases reaction|increases activity 12826277
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased activity of CASP7 protein]decreases reaction|increases activity 20299546
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CASP7 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CASP7 mRNAincreases expression 12167310
D019284 Thapsigargin Doxorubicin inhibits the reaction [Thapsigargin results in increased activity of and results in increased cleavage of CASP7 protein]decreases reaction|increases activity|increases cleavage 16298333
D019284 Thapsigargin Thapsigargin results in increased activity of and results in increased cleavage of CASP7 proteinincreases activity|increases cleavage 16298333
D014028 Tobacco Smoke Pollution Tobacco Smoke Pollution results in decreased expression of CASP7 mRNAdecreases expression 15289447
D014028 Tobacco Smoke Pollution Tobacco Smoke Pollution results in increased expression of CASP7 mRNAincreases expression 16137721
D014108 Tosylphenylalanyl Chloromethyl Ketone Tosylphenylalanyl Chloromethyl Ketone results in increased cleavage of and results in increased activity of CASP7 proteinincreases activity|increases cleavage 12821135
D014108 Tosylphenylalanyl Chloromethyl Ketone TP53 protein promotes the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased activity of CASP7 protein]increases activity|increases reaction 12821135
D014212 Tretinoin CRABP2 protein promotes the reaction [Tretinoin results in increased cleavage of and results in increased activity of CASP7 protein]increases activity|increases cleavage|increases reaction 16166294
D014212 Tretinoin Cycloheximide inhibits the reaction [Tretinoin results in increased expression of CASP7 mRNA]decreases reaction|increases expression 16166294
D014212 Tretinoin [Tretinoin co-treated with zoledronic acid] results in increased activity of CASP7 proteinaffects cotreatment|increases activity 20349282
D014212 Tretinoin Tretinoin results in increased cleavage of and results in increased activity of CASP7 proteinincreases activity|increases cleavage 16166294
D014212 Tretinoin Tretinoin results in increased expression of CASP7 mRNAincreases expression 16166294
D014212 Tretinoin Tretinoin promotes the reaction [arsenic trioxide results in increased cleavage of CASP7 protein]increases cleavage|increases reaction 15688020
C113580 U 0126 U 0126 inhibits the reaction [Acrolein results in increased activity of CASP7 protein]decreases reaction|increases activity 17196791
C113580 U 0126 U 0126 inhibits the reaction [Copper results in increased activity of CASP7 protein]decreases reaction|increases activity 16672322
D014700 Verapamil [Verapamil results in decreased expression of ABCB1] promotes the reaction [Doxorubicin results in increased activity of CASP7 protein]decreases expression|increases activity|increases reaction 15861398
C111237 vorinostat [decitabine co-treated with vorinostat] affects the expression of CASP7 mRNAaffects cotreatment|affects expression 17330099
C111237 vorinostat vorinostat results in increased cleavage of CASP7 proteinincreases cleavage 15897598
C009687 wortmannin wortmannin inhibits the reaction [Acrolein results in increased activity of CASP7 protein]decreases reaction|increases activity 17196791
C104536 xanthohumol xanthohumol results in increased cleavage of and results in increased activity of CASP7 proteinincreases activity|increases cleavage 15995977
C488234 XCT790 manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[XCT790 results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP7 protein]decreases reaction|increases abundance|increases activity 19464277
C488234 XCT790 [XCT790 results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP7 proteinincreases abundance|increases activity 19464277
C088658 zoledronic acid [Tretinoin co-treated with zoledronic acid] results in increased activity of CASP7 proteinaffects cotreatment|increases activity 20349282
C088658 zoledronic acid [zoledronic acid co-treated with Gossypol] results in increased activity of CASP7 proteinaffects cotreatment|increases activity 19825521
C088658 zoledronic acid zoledronic acid results in increased activity of CASP7 proteinincreases activity 19825521
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.7414745880
MESH:D000014 Abnormalities, Drug-Induced Disulfiram 10.0817676605
MESH:D000014 Abnormalities, Drug-Induced Terbutaline 10.0814610225
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 10.0815322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 2.7818287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.1417505938
MESH:D000163 Acquired Immunodeficiency Syndrome Disulfiram 4.789207937
MESH:D000168 Acrocephalosyndactylia U 0126 4.7117694057
MESH:D058186 Acute Kidney Injury resveratrol 6.7216538975
MESH:D058186 Acute Kidney Injury zoledronic acid 6.7219715164
MESH:D055371 Acute Lung Injury Acrolein 3.9820525806 21297076
MESH:D000210 Acute-Phase Reaction zoledronic acid 4.6920200999
MESH:D000230 Adenocarcinoma arsenic trioxide 10.4711798837 19825857
MESH:D000230 Adenocarcinoma Doxorubicin 10.4717418594
MESH:D000230 Adenocarcinoma Estradiol 10.4711473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 10.4714692618
MESH:D000230 Adenocarcinoma Fluorouracil 10.4717638652
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Tobacco Smoke Pollution 4.7315814487
MESH:D000236 Adenoma Diethylnitrosamine 5.156695378 10737359
MESH:D000236 Adenoma resveratrol 5.1515688382
MESH:D018248 Adenoma, Liver Cell DDT 12.9812597452
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 12.9819061943 18056438 16434500 17162532 19052882 17620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 12.9816835633
MESH:D011125 Adenomatous Polyposis Coli sulforafan 4.5717942926
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.9015276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.1017306315 16712894
MESH:D000382 Agricultural Workers' Diseases DDT 6.5216487989 12584743
MESH:D000382 Agricultural Workers' Diseases Paraquat 6.5211874814
MESH:D000419 Albuminuria Doxorubicin 8.9621441931
MESH:D000419 Albuminuria Raloxifene 8.9617308373 17451421
MESH:D000437 Alcoholism Disulfiram 4.3417079463 10841824 18968458
MESH:D019973 Alcohol-Related Disorders Curcumin 4.2817887948
OMIM:607154 ALLERGIC RHINITIS Etodolac 5.0816979129
MESH:D000505 Alopecia Tretinoin 2.9715955085
MESH:D000544 Alzheimer Disease Acrolein 9.7314715435 17570602 15207723
MESH:D000544 Alzheimer Disease Copper 9.7316410023 16325427 17119284 16962711 16866297 16886094
MESH:D000544 Alzheimer Disease Curcumin 9.7315590663
MESH:D000544 Alzheimer Disease Raloxifene 9.7315800139
MESH:D000544 Alzheimer Disease resveratrol 9.7316183991 16162502
MESH:D000686 Amyloidosis Terbutaline 4.877986221
MESH:D000690 Amyotrophic Lateral Sclerosis Copper 3.7610694572
MESH:D000740 Anemia Fluorouracil 6.3715504547 17963324 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.3711748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.5217084956
MESH:D018798 Anemia, Iron-Deficiency Copper 4.1816614410
MESH:D000799 Angioedema Acetaminophen 3.0410982225
MESH:D001008 Anxiety Disorders Pentobarbital 4.0811141031 18313124
MESH:D001161 Arteriosclerosis Acrolein 7.7715014928
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 7.7711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 13.1515885639
MESH:D001169 Arthritis, Experimental resveratrol 13.1517115116
MESH:D001169 Arthritis, Experimental Tosylphenylalanyl Chloromethyl Ketone 13.1518706406
MESH:D001169 Arthritis, Experimental Tretinoin 13.1516412693
MESH:D001172 Arthritis, Rheumatoid Curcumin 5.9516807698
MESH:D001172 Arthritis, Rheumatoid Tobacco Smoke Pollution 5.9519898480
MESH:D001172 Arthritis, Rheumatoid Tretinoin 5.9516292516
MESH:D001249 Asthma Mustard Gas 3.9010378619
MESH:D001249 Asthma Tretinoin 3.9016456186
MESH:D001260 Ataxia Telangiectasia Quercetin 4.1915336622
MESH:D050197 Atherosclerosis Acrolein 11.4217363696 16126721 16037261
MESH:D050197 Atherosclerosis Cadmium 11.4215687053
MESH:D050197 Atherosclerosis Curcumin 11.4218704882
MESH:D050197 Atherosclerosis resveratrol 11.4216873680 17967414
MESH:D001321 Autistic Disorder Acetaminophen 2.4218445737
MESH:D001321 Autistic Disorder Terbutaline 2.4217400887 16417856
MESH:D001327 Autoimmune Diseases Curcumin 13.8119761891
MESH:D001327 Autoimmune Diseases Quercetin 13.8119761891
MESH:D001327 Autoimmune Diseases sulforafan 13.8119761891
MESH:D001471 Barrett Esophagus Tretinoin 3.6516935849
MESH:D001768 Blister Mustard Gas 4.3719167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 11.2216206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 11.2212125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 11.2216206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 2.9915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.2115746008
MESH:D019046 Bone Marrow Neoplasms Dactinomycin 15.8414601052
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 15.8414601052
MESH:D019046 Bone Marrow Neoplasms Etoposide 15.8414601052
MESH:D001859 Bone Neoplasms Paclitaxel 8.4015867366
MESH:D001859 Bone Neoplasms zoledronic acid 8.4015867366 19442620 11697798 17312309 16121404 16778634
MESH:D001862 Bone Resorption zoledronic acid 3.998053405 18496637 11869084 16769263 15845617 18404659
MESH:D001930 Brain Injuries Nitroprusside 8.9414637104
MESH:D001930 Brain Injuries Raloxifene 8.9416580743
MESH:D002545 Brain Ischemia Curcumin 7.7216770732
MESH:D002545 Brain Ischemia resveratrol 7.7217600658
MESH:D001932 Brain Neoplasms Copper 15.3117079463
MESH:D001932 Brain Neoplasms Curcumin 15.3117596214
MESH:D001932 Brain Neoplasms Doxorubicin 15.3117150277
MESH:D001932 Brain Neoplasms KCC 009 15.3116170020
MESH:D001943 Breast Neoplasms marker/mechanism 16583263
MESH:D001943 Breast Neoplasms 2-methoxy-3-O-sulfamoyl-17-cyanomethylestra-1,3,5(10)-triene 29.2018026194
MESH:D001943 Breast Neoplasms 2-methoxyestradiol-3,17-O,O-bis(sulfamate) 29.2018223236 18026194 18506995 18985042
MESH:D001943 Breast Neoplasms Apigenin 29.2016541309 17132221
MESH:D001943 Breast Neoplasms bendamustine 29.2017667603
MESH:D001943 Breast Neoplasms Copper 29.2015986119 17079463
MESH:D001943 Breast Neoplasms Curcumin 29.2016243823 18593918 18462866 19250217
MESH:D001943 Breast Neoplasms DDT 29.2012709520 16792888
MESH:D001943 Breast Neoplasms decitabine 29.2019208741 18320071
MESH:D001943 Breast Neoplasms deguelin 29.2017035597 18593368
MESH:D001943 Breast Neoplasms Diethylnitrosamine 29.2017474063
MESH:D001943 Breast Neoplasms Disulfiram 29.2017026967
MESH:D001943 Breast Neoplasms Doxorubicin 29.2015692762 18382427 17983394 16935488 16595493 15939500 18234424 18695136 16826403 17426702 15993339 15567936 15994142 15136595 16322301 16264153 15634643 17369602 11325840 16115903 16096432 18628466 19526202 15668708
MESH:D001943 Breast Neoplasms Estradiol 29.2016675129 12948864 17261762 17018787 19861407 17289903 14630087 18497071
MESH:D001943 Breast Neoplasms Etoposide 29.2016322251
MESH:D001943 Breast Neoplasms Fluorouracil 29.2015136595 19217205 18357371 16595493 18608205 16557594 16110121
MESH:D001943 Breast Neoplasms Paclitaxel 29.2015136595 16273361 18223236 16244791 18234424 18323546 11325840 16115903
MESH:D001943 Breast Neoplasms Plant Preparations 29.2017398067
MESH:D001943 Breast Neoplasms Quercetin 29.2018628248
MESH:D001943 Breast Neoplasms Raloxifene 29.2016837676 17893378 17595753 17952589 17049068 15775269 17242785 16912660 17440819 15758505 15572757 17261762
MESH:D001943 Breast Neoplasms resveratrol 29.2016393696 17651959 17534123
MESH:D001943 Breast Neoplasms Tamoxifen 29.2017893378 18425577 19066611 11161223 18815881 20135344 17049068 19289846 17242785 19103187 19244106 18984771 19011961 20005174 18821012 18351453 19059307 18629630 17261762 19155303 21138602 18855134 21152245 16202921 16273361 15565566 19189212 15668708 19221464 19189210 19487384 20544844 17440819 19142967 20065188 19115204 20859285 16818667 19288272 20390343 19084267 19410462 18997820 19200415 16873071
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 29.2020435547
MESH:D001943 Breast Neoplasms Tretinoin 29.2016166294 16443354 16873071
MESH:D001943 Breast Neoplasms vorinostat 29.2016144943
MESH:D001943 Breast Neoplasms zoledronic acid 29.2016096432 18695136
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.3715286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.1717687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.8016813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.5911589617
MESH:D002105 Cadmium Poisoning Quercetin 4.7416962696
MESH:D002177 Candidiasis Disulfiram 5.0715325261
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.6716111702
MESH:D019559 Capillary Leak Syndrome Terbutaline 5.069428835 11713377
MESH:D002276 Carcinoid Tumor Doxorubicin 16.6116051944
MESH:D002276 Carcinoid Tumor Fluorouracil 16.6116051944
MESH:D002276 Carcinoid Tumor Streptozocin 16.6116051944
MESH:D002277 Carcinoma Curcumin 14.7018593918
MESH:D002277 Carcinoma Disulfiram 14.7017026967
MESH:D002277 Carcinoma Fluorouracil 14.7017121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 14.7016835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.7319066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.3516168501
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 42.6016705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 42.603084413
MESH:D006528 Carcinoma, Hepatocellular anthra(1,9-cd)pyrazol-6(2H)-one 42.6019418558
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 42.6015553829 16217749 11135700 14691202 15073043
MESH:D006528 Carcinoma, Hepatocellular AZD 6244 42.6017876044
MESH:D006528 Carcinoma, Hepatocellular DDT 42.6012597452
MESH:D006528 Carcinoma, Hepatocellular deguelin 42.6018575727
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 42.6019394651 18978308 19107877 17173139 19383236 16502159 19822196 10672840 18665156 19919837 17428255 16830150 10737359 16540662 16807293 20214788 19418558 19171122 20512989 16328049 20935162 17055752 20084675 16935385 18785209 19539802 18971187 20727157 21159647 19208518 11831363 17978847 16779866 18788625 18494052 19701751 20432363 16698587 18056438 16878318 19519916 16288022 20524982 16569478 18691550 17138121 16681979 20514400 17162532 17761372 20101231 18506893 18210153 3084413 18393292 19052882 3581430 20007298 19335982
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 42.6016234567 18059187 16023760 17876044
MESH:D006528 Carcinoma, Hepatocellular Estradiol 42.6016924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 42.6017045692 16799960 16332177 17971768 17088986 18930000
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 42.6016313753
MESH:D006528 Carcinoma, Hepatocellular Quercetin 42.6019519916 12508355
MESH:D006528 Carcinoma, Hepatocellular resveratrol 42.6016227395 19321006
MESH:D006528 Carcinoma, Hepatocellular SC 560 42.6016391822
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 42.6017306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 42.6016924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 42.601917145
MESH:D018827 Carcinoma, Lewis Lung resveratrol 3.8116675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung bortezomib 13.0216052434
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 13.0218414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung Disulfiram 13.0217026967
MESH:D002289 Carcinoma, Non-Small-Cell Lung Tobacco Smoke Pollution 13.0211212258
MESH:D002289 Carcinoma, Non-Small-Cell Lung zoledronic acid 13.0219233551
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.1817234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.0719014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 8.3416201981 1485588
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 8.3418695887
MESH:D002292 Carcinoma, Renal Cell zoledronic acid 8.3418507039
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.4212490120
MESH:D002294 Carcinoma, Squamous Cell Curcumin 23.8918462866
MESH:D002294 Carcinoma, Squamous Cell decitabine 23.8919215824
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 23.896189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 23.8916280240 18986760 17066447 16757204
MESH:D002294 Carcinoma, Squamous Cell Plant Preparations 23.8917418620
MESH:D002294 Carcinoma, Squamous Cell resveratrol 23.8916227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 23.8918572023
MESH:D002294 Carcinoma, Squamous Cell Tobacco Smoke Pollution 23.8911212258
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 23.8916051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 7.1817572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 7.1817572228
MESH:D006332 Cardiomegaly Copper 8.6217327471
MESH:D006332 Cardiomegaly Quercetin 8.6219794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 8.6216120746 18850075 18670907
MESH:D009202 Cardiomyopathies Doxorubicin 2.9717382496 16612575 15792986 17007740 17974986 16242529 17924179 17519947 16278810 16455267 17928571 15505089 16952015 17308081 15811867 16109756 16731534 17329180 16651473 15476868 17131338 18627295 17351982 16364871 16269455
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.6117334414 16243910
MESH:D002318 Cardiovascular Diseases Plant Preparations 9.0016862667
MESH:D002318 Cardiovascular Diseases Raloxifene 9.0015775269
MESH:D002318 Cardiovascular Diseases resveratrol 9.0015458977
MESH:D016893 Carotid Stenosis Plant Preparations 5.3515158307
MESH:D002386 Cataract Acetaminophen 9.4510977129
MESH:D002386 Cataract Disulfiram 9.4515003327 17936468
MESH:D002386 Cataract Tretinoin 9.4517460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 18.826135515
MESH:D002471 Cell Transformation, Neoplastic Cadmium 18.8217332340
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 18.8212371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 18.822727394 7505956 17174075 21159647
MESH:D002471 Cell Transformation, Neoplastic Estradiol 18.8218566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 18.8219524636 20056578
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.8016129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 7.0619052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.0616835633
MESH:D002779 Cholestasis Cyclosporine 5.7319486331
MESH:D002779 Cholestasis Ethinyl Estradiol 5.7317333356 11677210 15861022 16105132 17110522 16919318 17681005
MESH:D002822 Choriocarcinoma Tretinoin 4.3516461808
MESH:D019457 Chromosome Breakage Sodium Selenite 3.9815894690
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 4.408697196 12621046 15668235 15340226 16354765
MESH:D002972 Cleft Palate Tretinoin 4.409407595
MESH:D019970 Cocaine-Related Disorders Disulfiram 4.9619462300
MESH:D003072 Cognition Disorders Raloxifene 3.8515800139
MESH:D003092 Colitis Curcumin 11.6716782535 18200517 16804969
MESH:D003092 Colitis resveratrol 11.6716474422
MESH:D003092 Colitis Tretinoin 11.6717035595
MESH:D003103 Coloboma Curcumin 3.8318809619
MESH:D003110 Colonic Neoplasms arsenite 16.5015037631
MESH:D003110 Colonic Neoplasms Butyrates 16.5015936596
MESH:D003110 Colonic Neoplasms Curcumin 16.5016340194 19359593
MESH:D003110 Colonic Neoplasms decitabine 16.5017616700
MESH:D003110 Colonic Neoplasms Etodolac 16.5016004971
MESH:D003110 Colonic Neoplasms Fluorouracil 16.5018772588 17287894 17725105 16340194 16510598 17172411 15001691 17169374 17018589 17016597
MESH:D003110 Colonic Neoplasms Quercetin 16.5015741050 19056647 11134977 19440933 17148506 17191121 16640504
MESH:D003110 Colonic Neoplasms resveratrol 16.5016338953
MESH:D015179 Colorectal Neoplasms Acrolein 12.4417597105
MESH:D015179 Colorectal Neoplasms arsenic trioxide 12.4420501625
MESH:D015179 Colorectal Neoplasms decitabine 12.4418981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 12.4418802399 18259882
MESH:D015179 Colorectal Neoplasms Etodolac 12.4411076880
MESH:D015179 Colorectal Neoplasms Fluorouracil 12.4418509181 17594712 18383874 17255274 15289873 18949393 14970324 18288408 16303861 17016601 17454858 17094418 17401013 18802399 16282729 20501625 16524972 17695437 16331619 15148649 18448328 16391804
MESH:D015179 Colorectal Neoplasms Paclitaxel 12.4418802399
MESH:D015179 Colorectal Neoplasms Quercetin 12.4418852136 18095365
MESH:D015179 Colorectal Neoplasms resveratrol 12.4416550006
MESH:D000013 Congenital Abnormalities DDT 7.2015095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 7.2017141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 4.1218497527
MESH:D003324 Coronary Artery Disease Plant Preparations 3.6415158307
MESH:D003327 Coronary Disease resveratrol 3.2016507316
MESH:D023903 Coronary Restenosis arsenic trioxide 3.4312609071
MESH:D003371 Cough Terbutaline 4.7719679606
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 4.3110525206
MESH:D019465 Craniofacial Abnormalities Reactive Oxygen Species 4.3115736158
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.3120055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 4.319125849 17551590 9664655 10589399 14991402 16925845 9224671 8800419 9211117 9142499
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.2518551238
MESH:D003556 Cystitis Acrolein 4.5912161096
MESH:D007644 Darier Disease Fluorouracil 4.0016733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.3615213294
MESH:D003711 Demyelinating Diseases Tamoxifen 3.5919031437
MESH:D003865 Depressive Disorder, Major Raloxifene 3.4817474826
MESH:D003920 Diabetes Mellitus Sodium Selenite 7.3216285004
MESH:D003920 Diabetes Mellitus Streptozocin 7.3216285004
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 10.2919496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 10.2916873680
MESH:D003921 Diabetes Mellitus, Experimental Streptozocin 10.292177838 15831366 16684804 16286809 12446591 18603373 19496084 19586609 7637645 12644472 1374869 8740154 12093613 11055810 17442507 15298345 19960420 18715473 17874149 6379147 19298542 15862027 11260395 12083368
MESH:D003922 Diabetes Mellitus, Type 1 Streptozocin 3.3318603373
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 7.9618403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 7.9620387270
MESH:D003924 Diabetes Mellitus, Type 2 Streptozocin 7.9619586609 19647726
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 7.9617107852
MESH:D058065 Diabetic Cardiomyopathies Streptozocin 4.9416025228
MESH:D003928 Diabetic Nephropathies Curcumin 26.2018204486
MESH:D003928 Diabetic Nephropathies Estradiol 26.2019279558
MESH:D003928 Diabetic Nephropathies Raloxifene 26.2017308373 17451421 15920148
MESH:D003928 Diabetic Nephropathies resveratrol 26.2016286809
MESH:D003928 Diabetic Nephropathies Streptozocin 26.2019960420 19682444
MESH:D003928 Diabetic Nephropathies Tamoxifen 26.2019279558
MESH:D003930 Diabetic Retinopathy Streptozocin 4.6717662242
MESH:D003967 Diarrhea vorinostat 3.7720479100
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 13.7021346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 13.7017906064 11834606 18713872 16227642 12540782 19416960 19923254 11461765 11743745 18071297 2444490 14986274 19420014 12705907 11287661 15968718 19739265 17522070 11739529 11421492 12594235 14725611 11529661 16781746 10663392 12958197 12153990 16485898 19164858 10774834 14550746 12392966 10915739 19085960 17562736 16177239 16393943 19370779 16081117 16109766 15619225
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 13.7019107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 13.7017416283
MESH:D056486 Drug-Induced Liver Injury pyrazole 13.7012499123
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 13.7015131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 13.7020420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.2919426721
MESH:D004362 Drug Toxicity Doxorubicin 10.3118602426
MESH:D004362 Drug Toxicity Plant Preparations 10.3111033412
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 10.3111462148
MESH:D004381 Duodenal Ulcer Curcumin 3.3117351913
MESH:D004417 Dyspnea DDT 4.3716487989
MESH:D004487 Edema Mustard Gas 14.2811402378 11428647 11428631 9260866
MESH:D004487 Edema Raloxifene 14.2815860553
MESH:D004487 Edema resveratrol 14.288985016
MESH:D004487 Edema Staurosporine 14.288273558
MESH:D004487 Edema Tetrachlorodibenzodioxin 14.2812711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 9.2815322242 16714409 18230668
MESH:D004489 Edema, Cardiac Tretinoin 9.2818230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 15.8312538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 15.8315845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 15.8317872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 15.8319031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.3119294695
MESH:D016889 Endometrial Neoplasms 2-methoxyestradiol-3,17-O,O-bis(sulfamate) 17.4218450955
MESH:D016889 Endometrial Neoplasms Doxorubicin 17.4217359293
MESH:D016889 Endometrial Neoplasms Estradiol 17.4219148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Tamoxifen 17.4217893378 20544844 16202921 19155303
MESH:D016889 Endometrial Neoplasms Tretinoin 17.4216569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.339294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.3518037988
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.0817923197
MESH:D004890 Erythema Mustard Gas 4.379357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.3116302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 8.1012903497
MESH:D004938 Esophageal Neoplasms Fluorouracil 8.1015173087 16785472 17638652 16337965 16481741
MESH:D004938 Esophageal Neoplasms Paclitaxel 8.1016481741
MESH:D004938 Esophageal Neoplasms Plant Preparations 8.1016510608
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 6.7711564622
MESH:D005124 Eye Abnormalities Tretinoin 6.779664655 16938888
MESH:D005221 Fatigue vorinostat 4.8120479100
MESH:D005234 Fatty Liver arsenic trioxide 30.9315073043
MESH:D005234 Fatty Liver arsenite 30.9318296743
MESH:D005234 Fatty Liver Curcumin 30.9319297423
MESH:D005234 Fatty Liver Cyclosporine 30.9319224547
MESH:D005234 Fatty Liver Diethylnitrosamine 30.9320387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 30.9315345470
MESH:D005234 Fatty Liver Raloxifene 30.9317473493
MESH:D005234 Fatty Liver Tamoxifen 30.9319224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.7016709447
MESH:D005264 Femoral Fractures zoledronic acid 5.0416234978
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.6911858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.7414745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 8.8319069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 8.8319069698
MESH:D005355 Fibrosis arsenite 29.8518296743
MESH:D005355 Fibrosis Curcumin 29.8518705752
MESH:D005355 Fibrosis Cyclosporine 29.8512168785 12639820
MESH:D005355 Fibrosis Quercetin 29.8519474275
MESH:D005355 Fibrosis Terbutaline 29.8515467267
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 29.8520067830
MESH:D005355 Fibrosis Tretinoin 29.8517994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.5116904648
MESH:D005756 Gastritis Acetaminophen 2.8816983495
MESH:D005770 Gastrointestinal Neoplasms Curcumin 3.9218462866
MESH:D005833 Genital Neoplasms, Female sodium arsenite 3.8916452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.438708960
MESH:D005909 Glioblastoma Curcumin 16.3517596214
MESH:D005909 Glioblastoma Doxorubicin 16.3517150277
MESH:D005909 Glioblastoma KCC 009 16.3516170020
MESH:D005909 Glioblastoma Quercetin 16.3519804834
MESH:D005909 Glioblastoma Tretinoin 16.3517312396
MESH:D005910 Glioma Fluorouracil 4.8716145905
MESH:D005910 Glioma Quercetin 4.8717643826
MESH:D005911 Gliosis Paraquat 4.3611124998
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.7910696789
MESH:D006258 Head and Neck Neoplasms Curcumin 18.1018829502 18462866
MESH:D006258 Head and Neck Neoplasms decitabine 18.1019215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 18.1015692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 18.1015162350 15102660 18337622
MESH:D006258 Head and Neck Neoplasms Tretinoin 18.1016096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.3516084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 4.9211294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 4.929664655 14991402
MESH:D006331 Heart Diseases Doxorubicin 13.3616495754 17888722 14766674 16244371 16879835 12587719 18006777 16144979 16330681 18674790 16244372 17875725 16707910
MESH:D006331 Heart Diseases Mitoxantrone 13.3616019553
MESH:D006331 Heart Diseases Raloxifene 13.3611110106
MESH:D006331 Heart Diseases Streptozocin 13.3612093613
MESH:D006333 Heart Failure Doxorubicin 2.8117481944
MESH:D006394 Hemangiosarcoma Doxorubicin 3.1915692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.6315720958
MESH:D006463 Hemolytic-Uremic Syndrome Shiga Toxin 2 5.5916366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.6211000095
MESH:D006505 Hepatitis DDT 4.1916487989
MESH:D006521 Hepatitis, Chronic Copper 4.4817338147
MESH:D006527 Hepatolenticular Degeneration Copper 4.4017109627 19888908 17276780 17182432 16607473
MESH:D006529 Hepatomegaly DDT 6.382387028
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 6.3816120746 12621046 15340226
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.2717701891
MESH:D006558 Herpes Genitalis Estradiol 4.2315709030
MESH:D006561 Herpes Simplex Etoposide 7.5010809021
MESH:D006561 Herpes Simplex resveratrol 7.5016876885
MESH:D006689 Hodgkin Disease Doxorubicin 8.5017606976 18501091 15147373
MESH:D006689 Hodgkin Disease Etoposide 8.5017606976 16135485 15147373 16200630 18180244
MESH:D006689 Hodgkin Disease sodium arsenite 8.5012676792
MESH:D019584 Hot Flashes Estradiol 2.9617088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.2416959395 18606429 8697196 16354765 15340226
MESH:D006930 Hyperalgesia Acetaminophen 9.4216870215
MESH:D006930 Hyperalgesia Tretinoin 9.4216870215
MESH:D006930 Hyperalgesia zoledronic acid 9.4216769263
MESH:D006934 Hypercalcemia bortezomib 9.0618089816
MESH:D006934 Hypercalcemia zoledronic acid 9.0618089816 19622757
MESH:D006937 Hypercholesterolemia Curcumin 7.0218704882
MESH:D006937 Hypercholesterolemia resveratrol 7.0217188708
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.8016778211
MESH:D006943 Hyperglycemia Quercetin 3.3418262572 11834736
MESH:D006949 Hyperlipidemias resveratrol 3.3016873680
MESH:D006973 Hypertension Cyclosporine 12.3210903974
MESH:D006973 Hypertension Quercetin 12.3218356687
MESH:D006973 Hypertension Raloxifene 12.3215787275 17577099
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 12.3218850075 18670907
MESH:D006973 Hypertension Verapamil 12.3217700361
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.6017488730
MESH:D006985 Hyperventilation Terbutaline 5.3010895896
MESH:D006996 Hypocalcemia zoledronic acid 5.3912669777
MESH:D007008 Hypokalemia Terbutaline 5.3017292646
MESH:D007021 Hypospadias Ethinyl Estradiol 3.0416945680 16569931
MESH:D007022 Hypotension Isoflurane 4.2212967683
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 3.8817600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.7312013081
MESH:D007248 Infertility, Male DDT 19.0117192596 17157474
MESH:D007248 Infertility, Male decitabine 19.0117581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 19.0117937319
MESH:D007248 Infertility, Male Gossypol 19.0111202417 9639145
MESH:D007248 Infertility, Male Paraquat 19.014850670
MESH:D007248 Infertility, Male sodium arsenite 19.0112646999 15346721
MESH:D007249 Inflammation Curcumin 16.9018403477 16956363 17151092
MESH:D007249 Inflammation Diethylnitrosamine 16.9018785209
MESH:D007249 Inflammation Mustard Gas 16.9011428631 8975870 9357497 11428620 11428647 9260866 16001271 17524151 11402378
MESH:D007249 Inflammation resveratrol 16.9016366677
MESH:D007249 Inflammation Tamoxifen 16.9019457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 16.9012200463 12878042
MESH:D007249 Inflammation Tobacco Smoke Pollution 16.9018590791
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.8218200517 18596194
MESH:D007251 Influenza, Human Quercetin 8.5416624496
MESH:D007251 Influenza, Human resveratrol 8.5416624496
MESH:D007333 Insulin Resistance Estradiol 5.5616627594 16393666
MESH:D007333 Insulin Resistance Sodium Selenite 5.5614714311
MESH:D007410 Intestinal Diseases Tretinoin 3.0017994277
MESH:D007414 Intestinal Neoplasms Curcumin 3.5210783313
MESH:D002532 Intracranial Aneurysm Reactive Oxygen Species 4.3019381132
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 7.5516580747
MESH:D007569 Jaw Abnormalities Tretinoin 7.5515992940 17551590
MESH:D007627 Keloid Quercetin 4.1817086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.6415604871
MESH:D007674 Kidney Diseases Acetaminophen 33.2012587719 15629191
MESH:D007674 Kidney Diseases Acrolein 33.2012488133
MESH:D007674 Kidney Diseases Cadmium 33.2016226777 16962696 16322080
MESH:D007674 Kidney Diseases Cadmium Chloride 33.2016962696
MESH:D007674 Kidney Diseases Cyclosporine 33.208314463 10903974 18776723
MESH:D007674 Kidney Diseases Doxorubicin 33.2015699352 16775033 15369732
MESH:D007674 Kidney Diseases Estradiol 33.2015618244
MESH:D007674 Kidney Diseases Quercetin 33.2016962696
MESH:D007674 Kidney Diseases sodium arsenite 33.2020008137
MESH:D007674 Kidney Diseases Streptozocin 33.2012093613
MESH:D007676 Kidney Failure, Chronic Copper 7.9816518626
MESH:D007676 Kidney Failure, Chronic Doxorubicin 7.9816707910
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 16.4016705839
MESH:D007680 Kidney Neoplasms Cyclosporine 16.4012371664
MESH:D007680 Kidney Neoplasms Estradiol 16.4015610895
MESH:D007680 Kidney Neoplasms Fluorouracil 16.4016985049
MESH:D007680 Kidney Neoplasms Tamoxifen 16.4018625569
MESH:D007859 Learning Disorders Copper 7.8017134702
MESH:D007859 Learning Disorders DDT 7.807589230
MESH:D007889 Leiomyoma Curcumin 8.7218555241
MESH:D007889 Leiomyoma Raloxifene 8.7216973256
MESH:D053609 Lethargy Terbutaline 5.5110895896
MESH:D007938 Leukemia 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 18.6012970779
MESH:D007938 Leukemia arsenic trioxide 18.6015070760
MESH:D007938 Leukemia Curcumin 18.6018462866
MESH:D007938 Leukemia decitabine 18.6019235587 18980019
MESH:D007938 Leukemia Quercetin 18.6017468513
MESH:D007938 Leukemia Tretinoin 18.6017143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.3516085563
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell bendamustine 8.6818980985
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Disulfiram 8.6817026967
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Mitoxantrone 8.6818172266
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 17.4012560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell bortezomib 17.4018089816
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 17.4016106398
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell zoledronic acid 17.4018089816
MESH:D007948 Leukemia, Monocytic, Acute anthra(1,9-cd)pyrazol-6(2H)-one 21.6716972261
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 21.6716972261
MESH:D007948 Leukemia, Monocytic, Acute PD 98059 21.6716972261
MESH:D007948 Leukemia, Monocytic, Acute U 0126 21.6716972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 2.8114633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 11.8819077051
MESH:D007951 Leukemia, Myeloid decitabine 11.8818454857 17236224 19117987
MESH:D007951 Leukemia, Myeloid Tretinoin 11.8819285840 16932348 16482212
MESH:D015470 Leukemia, Myeloid, Acute marker/mechanism 17330099
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 6.9619850784 16467208 17050201 16968895 20471514
MESH:D015470 Leukemia, Myeloid, Acute bortezomib 6.9620471514
MESH:D015470 Leukemia, Myeloid, Acute decitabine 6.9617679729 18206229 18460780 19387464 19010910 18704418
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 6.9619850784 16294345 17596541
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.6618055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 9.5019035177 12018890 19642359 17869043 17107899 11161223 17712046 15622746 12712474 16966277 19075265 17217047 9834237 17649720 11468182 16823087 16330433 12679006 15336539 16891316 15748426 15213294 16112521 19225113 16331271
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 9.5016087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 9.5017217047 17506722 16140955 19225113 19035177 15748426 9834237 17301526 17361223 19029980 17339181 16766008 17294898 17368321 16823087 16935935 19642359 12679006 17649720 19075265 16788101 16331271 17712046 16891316 17107899
MESH:D015458 Leukemia, T-Cell arsenic trioxide 9.2116882451
MESH:D015458 Leukemia, T-Cell Curcumin 9.2116106398
MESH:D017880 Limb Deformities, Congenital Disulfiram 6.6417676605
MESH:D017880 Limb Deformities, Congenital Tretinoin 6.649224671
MESH:D008064 Lipidoses Tamoxifen 2.5615342952 17567588
MESH:D008080 Liposarcoma Paclitaxel 4.0917353645
MESH:D008103 Liver Cirrhosis arsenite 5.1718296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 5.1720032147 18522880 18407596 19638242 18665156
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 10.3718006644 17355460 18705752
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 10.3716439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 10.3714716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Plant Preparations 10.3717724770
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 10.3712741479
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 10.3718564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 10.3712878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 10.3716248980 18397230
MESH:D008107 Liver Diseases Acetaminophen 7.0416610002 16611625 12587719 12969438 19784758 19014921 11587558 19460945
MESH:D008107 Liver Diseases Curcumin 7.0416956363
MESH:D008107 Liver Diseases DDT 7.0415729006
MESH:D008107 Liver Diseases Diethylnitrosamine 7.0417034775
MESH:D017114 Liver Failure, Acute Acetaminophen 2.5417185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 33.057678174
MESH:D008113 Liver Neoplasms arsenic trioxide 33.0514682389
MESH:D008113 Liver Neoplasms Copper 33.0520302851
MESH:D008113 Liver Neoplasms DDT 33.0515975961 11948501
MESH:D008113 Liver Neoplasms Diethylnitrosamine 33.0519638242 21167192 19294768 9163691 18648771 20434301 19499222 19256749 20101389 19850985 19690152 19551842 20137499 2422723 12771043 19090486 19642983 19073162 19254457 20492335 19255062 10737359 20583210 15885732 15175105 20501860 2862719 21071580 19996281 20118626 12112319 20405173 18977376 18978307 19833225 19426721 16942905 21047994 18644402 19427195 19812893 18754104 21278145 20452335
MESH:D008113 Liver Neoplasms Fluorouracil 33.0516603448 15113037 18383874 17045692
MESH:D008113 Liver Neoplasms Quercetin 33.0518980244
MESH:D008113 Liver Neoplasms resveratrol 33.0519321006 19073162 20405173 19812893
MESH:D008113 Liver Neoplasms sodium arsenite 33.0515276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 33.0516684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 33.0516984957
MESH:D008113 Liver Neoplasms XCT790 33.0519464277
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 16.346135515 2876784 2876786
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 16.3420377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 16.3417174075 19009564 21159647 16267830 17854601 9362446 17942915 18282651 2563599 19539802 18308698 16842330 18164116 19519916 18253720 18775883 19004024 3124819 18093689 19126423 18079962 18544905
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 16.3416842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Quercetin 16.3419519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 16.3412151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.7315213294
MESH:D008171 Lung Diseases Acrolein 9.1811504702
MESH:D008171 Lung Diseases Mustard Gas 9.1818702808 18161513
MESH:D008171 Lung Diseases sodium arsenite 9.1819095001
MESH:D008175 Lung Neoplasms arsenic trioxide 21.3211798837 19825857
MESH:D008175 Lung Neoplasms arsenite 21.3216809336
MESH:D008175 Lung Neoplasms Curcumin 21.3219359593 18462866 16243823
MESH:D008175 Lung Neoplasms deguelin 21.3219336726 16288123
MESH:D008175 Lung Neoplasms Diethylnitrosamine 21.326695378 20970405 20512841 21163286
MESH:D008175 Lung Neoplasms Doxorubicin 21.3217418594 6189445
MESH:D008175 Lung Neoplasms Fluorouracil 21.3215246190
MESH:D008175 Lung Neoplasms Mustard Gas 21.323148597 8781369
MESH:D008175 Lung Neoplasms Quercetin 21.3216280456
MESH:D008175 Lung Neoplasms sodium arsenite 21.3217306315 17077188 16712894 15276417 19931552
MESH:D008175 Lung Neoplasms Tamoxifen 21.3218625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 21.3219555203 11884234
MESH:D008175 Lung Neoplasms Tobacco Smoke Pollution 21.3211091918 16288123 12111688 3440675
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.0015086387
MESH:D008223 Lymphoma bortezomib 17.1516098063
MESH:D008223 Lymphoma Curcumin 17.1518462866
MESH:D008223 Lymphoma decitabine 17.1519470736
MESH:D008223 Lymphoma Doxorubicin 17.1516098063
MESH:D008223 Lymphoma Etoposide 17.1512854902 12556972
MESH:D016393 Lymphoma, B-Cell bortezomib 13.0716675587
MESH:D016393 Lymphoma, B-Cell resveratrol 13.0717088997
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 13.0714737004
MESH:D020522 Lymphoma, Mantle-Cell bendamustine 5.5118980985
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 10.8117654614
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 10.8114749477
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 10.8114749477
MESH:D016399 Lymphoma, T-Cell Curcumin 9.0116173963
MESH:D016399 Lymphoma, T-Cell Doxorubicin 9.0115621674
MESH:D016410 Lymphoma, T-Cell, Cutaneous vorinostat 4.9120479100
MESH:D015674 Mammary Neoplasms, Animal resveratrol 7.4015688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 7.4019428831
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 12.9815458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 12.9811807958 16891317 11408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 12.988985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 12.9814580682 19196722 11731420 19196723 16827153
MESH:D008325 Mammary Neoplasms, Experimental zoledronic acid 12.9817312309
MESH:D020149 Manganese Poisoning Estradiol 9.9819453300
MESH:D020149 Manganese Poisoning Tamoxifen 9.9819453300
MESH:D008527 Medulloblastoma bortezomib 5.5919213072
MESH:D008527 Medulloblastoma Tretinoin 5.5917453147
MESH:D008545 Melanoma Curcumin 19.9617885582 18462866
MESH:D008545 Melanoma decitabine 19.9617785578 16505122
MESH:D008545 Melanoma Disulfiram 19.9615367699
MESH:D008545 Melanoma Doxorubicin 19.9616827129
MESH:D008545 Melanoma Paclitaxel 19.9612025231 16342250 12040289
MESH:D008545 Melanoma Reactive Oxygen Species 19.9617992120
MESH:D008545 Melanoma resveratrol 19.9617992120
MESH:D008545 Melanoma sodium arsenite 19.9619082730 16487513
MESH:D008545 Melanoma Tamoxifen 19.9619393235 12393984
MESH:D008545 Melanoma Tretinoin 19.9616752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.4015990972
MESH:D008546 Melanoma, Experimental Acetaminophen 8.4319513568
MESH:D008546 Melanoma, Experimental Acrolein 8.4310803710
MESH:D008569 Memory Disorders Curcumin 3.4117263510
MESH:D008591 Meningomyelocele Tretinoin 3.6516940565
MESH:D007706 Menkes Kinky Hair Syndrome Copper 5.0917109627 17268249
MESH:D008654 Mesothelioma Doxorubicin 5.3217638057
MESH:D008654 Mesothelioma zoledronic acid 5.3216675582
MESH:D008659 Metabolic Diseases resveratrol 3.6617112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 3.9816801185
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.7815792986
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 4.7515863610
MESH:D009062 Mouth Neoplasms Fluorouracil 11.0218986760 16757204
MESH:D009062 Mouth Neoplasms Plant Preparations 11.0217418620
MESH:D009062 Mouth Neoplasms Tobacco Smoke Pollution 11.0215006635
MESH:D052016 Mucositis Doxorubicin 4.0017415656
MESH:D009101 Multiple Myeloma arsenic trioxide 29.4719417148 15949261 14977855 11468182 19549372
MESH:D009101 Multiple Myeloma bortezomib 29.4719112201 19372569 19112817
MESH:D009101 Multiple Myeloma Curcumin 29.4719372569
MESH:D009101 Multiple Myeloma decitabine 29.4718172295
MESH:D009101 Multiple Myeloma Paclitaxel 29.4714749477
MESH:D009101 Multiple Myeloma Raloxifene 29.4716497877
MESH:D009101 Multiple Myeloma resveratrol 29.4716267019 16490592 17164350 17049120 14749477 17935668
MESH:D009101 Multiple Myeloma zoledronic acid 29.4716996129 18089719 19621390
MESH:D009134 Muscular Atrophy, Spinal Curcumin 9.8017962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 9.8017962980
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.8718349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 9.3516105982 16882451
MESH:D009190 Myelodysplastic Syndromes decitabine 9.3518608210 16882708 19157545 19010910
MESH:D009190 Myelodysplastic Syndromes Tretinoin 9.3517596541
MESH:D009203 Myocardial Infarction Doxorubicin 7.2415857846 19429709
MESH:D009203 Myocardial Infarction Quercetin 7.2419595682
MESH:D009203 Myocardial Infarction resveratrol 7.2417125593 16317513 16456233 17188708 17015251 16525036
MESH:D017202 Myocardial Ischemia resveratrol 6.8517125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 6.8512213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 6.4616810080
MESH:D015428 Myocardial Reperfusion Injury Quercetin 6.4619207477
MESH:D009205 Myocarditis resveratrol 3.9717322642
MESH:D009232 Myxoma Raloxifene 4.7516343187
MESH:D009325 Nausea vorinostat 4.7220479100
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.087678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 13.0916624393
MESH:D009361 Neoplasm Invasiveness Curcumin 13.0918495463
MESH:D009361 Neoplasm Invasiveness Disulfiram 13.0918047805
MESH:D009362 Neoplasm Metastasis bendamustine 21.1017667603
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 21.103581430 9029167
MESH:D009362 Neoplasm Metastasis Disulfiram 21.1015367699
MESH:D009362 Neoplasm Metastasis Doxorubicin 21.1018259882
MESH:D009362 Neoplasm Metastasis Paclitaxel 21.1015867366
MESH:D009362 Neoplasm Metastasis Tamoxifen 21.1019393235
MESH:D009362 Neoplasm Metastasis zoledronic acid 21.1017312309 15867366 19139120
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.1919410462
MESH:D009369 Neoplasms 2-methoxyestradiol-3,17-O,O-bis(sulfamate) 34.7519156141 18630502 18841154
MESH:D009369 Neoplasms Acrolein 34.7517329238
MESH:D009369 Neoplasms DDT 34.758820588
MESH:D009369 Neoplasms decitabine 34.7517925555 19116145 19470736
MESH:D009369 Neoplasms deguelin 34.7517764071
MESH:D009369 Neoplasms Disulfiram 34.7517079463
MESH:D009369 Neoplasms Fluorouracil 34.7518600527 18239605 16928823
MESH:D009369 Neoplasms Mitoxantrone 34.7516640825
MESH:D009369 Neoplasms Quercetin 34.7515185748
MESH:D009369 Neoplasms sodium arsenite 34.7511559025
MESH:D009369 Neoplasms TDP 521252 34.7516432175
MESH:D009369 Neoplasms Tretinoin 34.7516594593 16946489
MESH:D009374 Neoplasms, Experimental resveratrol 6.698985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 6.6920056578
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 8.1912497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 8.1919200415 19189210 19196722
MESH:D009389 Neovascularization, Pathologic arsenite 17.9015738583
MESH:D009389 Neovascularization, Pathologic Copper 17.9017308104
MESH:D009389 Neovascularization, Pathologic Disulfiram 17.9015367699
MESH:D009389 Neovascularization, Pathologic Estradiol 17.9017289903
MESH:D009393 Nephritis Acrolein 5.4812653641
MESH:D009401 Nephrosis Doxorubicin 4.0016636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.6417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 7.0318481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 7.0315640375 16889571
MESH:D009410 Nerve Degeneration Paraquat 6.5416893418
MESH:D009410 Nerve Degeneration Rotenone 6.5417356569 15790535 18619942
MESH:D009421 Nervous System Malformations Estradiol 12.0011399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 12.0014600291
MESH:D009421 Nervous System Malformations Tretinoin 12.009125849
MESH:D009423 Nervous System Neoplasms Curcumin 4.8318462866
MESH:D009436 Neural Tube Defects arsenic trioxide 8.8910525206
MESH:D009436 Neural Tube Defects sodium arsenite 8.8912854658
MESH:D009436 Neural Tube Defects Tretinoin 8.899142499
MESH:D009447 Neuroblastoma Doxorubicin 2.8015555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 14.7218514411
MESH:D019636 Neurodegenerative Diseases Acrolein 14.7211342003
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 14.7220387270
MESH:D019636 Neurodegenerative Diseases resveratrol 14.7217652729
MESH:D020078 Neurogenic Inflammation Quercetin 8.2617929310
MESH:D020078 Neurogenic Inflammation resveratrol 8.2617929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.3120387270
MESH:D020258 Neurotoxicity Syndromes Disulfiram 6.5611005259
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 6.5616436463
MESH:D009503 Neutropenia Mustard Gas 3.257688884 16761898
MESH:D009765 Obesity Curcumin 2.5019297423
MESH:D007752 Obstetric Labor, Premature Terbutaline 5.3114998686
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 2.7416049721
MESH:D010014 Osteolysis Paclitaxel 9.6715867366
MESH:D010014 Osteolysis zoledronic acid 9.6715867366
MESH:D010024 Osteoporosis Curcumin 8.9318719352
MESH:D010024 Osteoporosis Raloxifene 8.9317882678 19059307 15775268
MESH:D010024 Osteoporosis zoledronic acid 8.9317882678
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 12.6919495926
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 12.6917893378 17823083 15579764 15758505
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 12.6917513867
MESH:D012516 Osteosarcoma Disulfiram 8.1718047805
MESH:D012516 Osteosarcoma Doxorubicin 8.1715930896
MESH:D010051 Ovarian Neoplasms 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 32.2916211241
MESH:D010051 Ovarian Neoplasms arsenic trioxide 32.2916624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Curcumin 32.2919020741 18462866
MESH:D010051 Ovarian Neoplasms decitabine 32.2919331143 19259094
MESH:D010051 Ovarian Neoplasms Disulfiram 32.2917026967
MESH:D010051 Ovarian Neoplasms Estradiol 32.2919401270
MESH:D010051 Ovarian Neoplasms Paclitaxel 32.2911161223
MESH:D010051 Ovarian Neoplasms Quercetin 32.2919005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 32.2915276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 32.2916936753
MESH:D010051 Ovarian Neoplasms U 0126 32.2916211241
MESH:D010146 Pain Acetaminophen 7.5816870215
MESH:D010146 Pain Tretinoin 7.5816870215
MESH:D010146 Pain zoledronic acid 7.5816475674
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 26.6515580305
MESH:D010190 Pancreatic Neoplasms Curcumin 26.6519401701 17440100 19196508
MESH:D010190 Pancreatic Neoplasms decitabine 26.6519294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 26.6516540662
MESH:D010190 Pancreatic Neoplasms Etoposide 26.6519003803
MESH:D010190 Pancreatic Neoplasms Fluorouracil 26.6516929163 19003803 15113037 16500647
MESH:D010190 Pancreatic Neoplasms Quercetin 26.6516965848
MESH:D010190 Pancreatic Neoplasms Reactive Oxygen Species 26.6515580305
MESH:D010190 Pancreatic Neoplasms Tretinoin 26.6515976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 2.9511578682
MESH:D010235 Paraganglioma arsenic trioxide 3.4319927285
MESH:D010300 Parkinson Disease Acrolein 6.6717690948
MESH:D010300 Parkinson Disease Paraquat 6.6716510128 15451049 15824117 12911755 16140633 11445065 11124998 11181820
MESH:D010300 Parkinson Disease Rotenone 6.6711445065 16412576 11535288 19232380 19114014 18619942 15451049 16140633 18191903
MESH:D010302 Parkinson Disease, Secondary Paraquat 3.6616190885
MESH:D020734 Parkinsonian Disorders Rotenone 3.3815795934 18197244 15927086 15574749
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.4412520081
MESH:D016491 Peripheral Vascular Diseases Cadmium 4.5915687053
MESH:D010538 Peritonitis Isoflurane 4.4617414419
MESH:D010787 Photosensitivity Disorders Acrolein 4.9411550810
MESH:D003557 Phyllodes Tumor Doxorubicin 4.3517983394
MESH:D010997 Pleural Neoplasms Doxorubicin 4.3517638057
MESH:D011014 Pneumonia Paraquat 3.6712504350
MESH:D011041 Poisoning Mustard Gas 3.0815727166
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.8118163543
MESH:D011230 Precancerous Conditions Cyclosporine 11.3912371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 11.392563599
MESH:D011230 Precancerous Conditions Quercetin 11.3919056647
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 6.9916679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 6.9911896295 11399792 11118676 11222880
MESH:D055728 Primary Myelofibrosis decitabine 3.9617616702
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.1720887781
MESH:D011471 Prostatic Neoplasms 2-methoxy-3-O-sulfamoyl-17-cyanomethylestra-1,3,5(10)-triene 17.1718026194
MESH:D011471 Prostatic Neoplasms 2-methoxyestradiol-3,17-O,O-bis(sulfamate) 17.1718985042 18026194
MESH:D011471 Prostatic Neoplasms AGN 194204 17.1716000583
MESH:D011471 Prostatic Neoplasms Apigenin 17.1717132221
MESH:D011471 Prostatic Neoplasms arsenic trioxide 17.1719131511
MESH:D011471 Prostatic Neoplasms Cadmium 17.1717075824
MESH:D011471 Prostatic Neoplasms Copper 17.1717308104 17079463
MESH:D011471 Prostatic Neoplasms Curcumin 17.1718226269 12497104 11398177 18156803 18769126 15129424 10851300
MESH:D011471 Prostatic Neoplasms DDT 17.1712584743
MESH:D011471 Prostatic Neoplasms Disulfiram 17.1719789329
MESH:D011471 Prostatic Neoplasms Doxorubicin 17.1715749863 15897917 16888761 18437689 16868541 16729912
MESH:D011471 Prostatic Neoplasms Estradiol 17.1716740699
MESH:D011471 Prostatic Neoplasms Etoposide 17.1717172428
MESH:D011471 Prostatic Neoplasms Fluorouracil 17.1718626508 19082440
MESH:D011471 Prostatic Neoplasms methylselenic acid 17.1716205645
MESH:D011471 Prostatic Neoplasms Paclitaxel 17.1717136230 17172428 16729912 16356831
MESH:D011471 Prostatic Neoplasms Quercetin 17.1714715546 17292933
MESH:D011471 Prostatic Neoplasms Raloxifene 17.1715731164 16220300 16536755
MESH:D011471 Prostatic Neoplasms resveratrol 17.1717804756 17675339 17636462 16731767 17718901 15767336
MESH:D011471 Prostatic Neoplasms sodium arsenite 17.1716039940
MESH:D011471 Prostatic Neoplasms Sodium Selenite 17.1718760546
MESH:D011471 Prostatic Neoplasms Tamoxifen 17.1715067354
MESH:D011471 Prostatic Neoplasms vorinostat 17.1717218635
MESH:D011471 Prostatic Neoplasms zoledronic acid 17.1719103299 12438248
MESH:D011507 Proteinuria Tretinoin 2.8816636307
MESH:D011537 Pruritus Ethinyl Estradiol 6.9315861022 16919318
MESH:D011537 Pruritus Mustard Gas 6.9318058305
MESH:D011565 Psoriasis Cyclosporine 1.8916882103
MESH:D011625 Pterygium Tretinoin 4.0016723453
MESH:D011654 Pulmonary Edema Terbutaline 4.7210903255
MESH:D011656 Pulmonary Emphysema Curcumin 3.8319168576
MESH:D011658 Pulmonary Fibrosis Mustard Gas 4.5917266442 17720292 17894541 17620002 10334151
MESH:D011658 Pulmonary Fibrosis Paraquat 4.5916324872 17997886
MESH:D011693 Purpura Raloxifene 4.7515770314
MESH:D012004 Rectal Neoplasms Fluorouracil 3.3316160472 18286688 18722050 15538739
MESH:D012021 Reflex, Abnormal Pentobarbital 5.2310930210
MESH:D051437 Renal Insufficiency Acrolein 8.0512732208
MESH:D051437 Renal Insufficiency Doxorubicin 8.0517922066
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.7816325855
MESH:D015427 Reperfusion Injury resveratrol 2.8216314181 17058453 17520802 16317513 15827377
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 11.1918379247 10666014
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 11.1911700416
MESH:D012128 Respiratory Distress Syndrome, Adult Terbutaline 11.192878809
MESH:D012135 Respiratory Sounds Paraquat 7.4011874814
MESH:D012135 Respiratory Sounds Tobacco Smoke Pollution 7.4018410779
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.0818990726
MESH:D012162 Retinal Degeneration Paraquat 3.2516458197
MESH:D012174 Retinitis Pigmentosa manganese(III)-tetrakis(4-benzoic acid)porphyrin 4.3216849425
MESH:D012208 Rhabdomyosarcoma decitabine 8.5119155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 8.5116116481 16283617
MESH:D012509 Sarcoma Curcumin 7.2618462866
MESH:D012509 Sarcoma Doxorubicin 7.2615675481 17710206 16767912 17203757 18313854 15625365
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 24.3716646077
MESH:D012512 Sarcoma, Ewing's Dactinomycin 24.3714601052
MESH:D012512 Sarcoma, Ewing's Doxorubicin 24.3716326096 14601052
MESH:D012512 Sarcoma, Ewing's Etoposide 24.3714601052
MESH:D012512 Sarcoma, Ewing's zoledronic acid 24.3716121404
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.0017846226
MESH:D012554 Schistosomiasis japonica Quercetin 4.7416862918
MESH:D012559 Schizophrenia Copper 2.9516842975
MESH:D012640 Seizures 2,6-dinitrotoluene 7.0518551238
MESH:D012640 Seizures Nitrazepam 7.059844417
MESH:D012640 Seizures Pentobarbital 7.0510087439 9754883
MESH:D018805 Sepsis Curcumin 7.6018389075
MESH:D018805 Sepsis Isoflurane 7.6017414419
MESH:D012772 Shock, Septic Terbutaline 4.713431524
MESH:D012871 Skin Diseases Mustard Gas 2.4515451306 16961503 12880345
MESH:D012878 Skin Neoplasms deguelin 20.3616041863
MESH:D012878 Skin Neoplasms Doxorubicin 20.3615692506
MESH:D012878 Skin Neoplasms resveratrol 20.368985016 15837718
MESH:D012878 Skin Neoplasms sodium arsenite 20.3619524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 20.3616192470
MESH:D012878 Skin Neoplasms Tobacco Smoke Pollution 20.3618590791
MESH:D012878 Skin Neoplasms Tretinoin 20.3616467112
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.8015625365 17203757 16767912
MESH:D013088 Spermatocele Ethinyl Estradiol 8.9016709447
MESH:D013088 Spermatocele Tamoxifen 8.9016709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.2519457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.1612854658
MESH:D013274 Stomach Neoplasms arsenic trioxide 6.5617007042
MESH:D013274 Stomach Neoplasms decitabine 6.5619037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 6.5618456281
MESH:D013274 Stomach Neoplasms Fluorouracil 6.5616424979 17522103 18396642 15786421 16951190 19084572 19015929 17172411 17498489 18567086
MESH:D013274 Stomach Neoplasms Paclitaxel 6.5618506536 18396642
MESH:D013274 Stomach Neoplasms Tretinoin 6.5617261132
MESH:D013276 Stomach Ulcer Curcumin 2.8319188055 16631530
MESH:D020521 Stroke Acrolein 6.9416269634
MESH:D020521 Stroke Raloxifene 6.9416837676
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.7816321402
MESH:D013375 Substance Withdrawal Syndrome Pentobarbital 4.2811529278 9754883
MESH:D013610 Tachycardia Nitroprusside 9.1315306635
MESH:D013610 Tachycardia Terbutaline 9.1310895896
MESH:D024801 Tauopathies Paclitaxel 4.0316930453
MESH:D013733 Testicular Diseases pyrazole 4.046499806
MESH:D013921 Thrombocytopenia vorinostat 4.2820479100
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.8911994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.4815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.1012697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 19.9719014326
MESH:D013964 Thyroid Neoplasms Butyrates 19.9717967635
MESH:D013964 Thyroid Neoplasms decitabine 19.9717967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 19.977505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 19.9716010429 17909728
MESH:D013964 Thyroid Neoplasms Tretinoin 19.9716026305 17045167
MESH:D013978 Tibial Fractures Estradiol 11.0519048282
MESH:D013978 Tibial Fractures Raloxifene 11.0519048282
MESH:D014062 Tongue Neoplasms Fluorouracil 12.5516280240
MESH:D014062 Tongue Neoplasms resveratrol 12.5516227395
MESH:D014062 Tongue Neoplasms Tretinoin 12.5516051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.1815213294
MESH:D014376 Tuberculosis Tretinoin 2.6816040207
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 32.8416049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 32.8411780464 20435036 12845720 12973940
MESH:D001749 Urinary Bladder Neoplasms Curcumin 32.8418593936
MESH:D001749 Urinary Bladder Neoplasms decitabine 32.8417616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 32.8417653716
MESH:D001749 Urinary Bladder Neoplasms Plant Preparations 32.8411251952
MESH:D001749 Urinary Bladder Neoplasms Quercetin 32.8416720314
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 32.8417572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 32.8411723127 16452187 16712894 17306315
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 32.8417572228 16712894 8653321
MESH:D001749 Urinary Bladder Neoplasms Tobacco Smoke Pollution 32.8412846360
MESH:D014565 Urogenital Neoplasms Curcumin 4.4718462866
MESH:D014570 Urologic Diseases DDT 4.8316487989
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 3.5310091137
MESH:D014581 Urticaria Acetaminophen 2.2610982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 16.9416803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 16.9417473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 16.9411813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 16.9416129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 7.0114692618
MESH:D014594 Uterine Neoplasms resveratrol 7.0117044934
MESH:D014604 Uveal Neoplasms decitabine 10.1617785578
MESH:D014604 Uveal Neoplasms Tretinoin 10.1616752155
MESH:D014605 Uveitis Cyclosporine 3.181336536
MESH:D014652 Vascular Diseases sodium arsenite 3.6417056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.7912125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.4016837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.8214671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 7.7917678736 17638931 17334414 16364871
MESH:D018487 Ventricular Dysfunction, Left resveratrol 7.7917488730
MESH:D014820 Vitiligo Tretinoin 3.3016761959
MESH:D014846 Vulvar Neoplasms Raloxifene 4.7516343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.4415886252
MESH:D009396 Wilms Tumor Tretinoin 3.2816287080
MESH:D014985 Xerophthalmia Cyclosporine 3.6417120751
Pathway ID Pathway Name
KEGG:05010 Alzheimer's disease
REACT:578 Apoptosis
KEGG:04210 Apoptosis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA26091
    • No data
    Releated disease ID Related disease Name
    PA445742Stomach Neoplasms
    Releated drug ID Related drug Name
    PA449957ibuprofen
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB03384 - Fica
    DB03762 - Dica
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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