Annotation Detail for FAM160A2
Basic Information Top
| Gene Symbol: | FAM160A2 ( C11orf56,DKFZp566M1046,FLJ22665,KIAA1759 ) |
|---|---|
| Gene Full Name: | family with sequence similarity 160, member A2 |
| Band: | 11p15.4 |
| Quick Links | Entrez ID:84067; OMIM: NA; Uniprot ID:F16A2_HUMAN; ENSEMBL ID: ENSG00000051009; HGNC ID: 25378 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of FAM160A2 mRNA | affects expression | 17562736 |
| C014707 | nitrosobenzylmethylamine | nitrosobenzylmethylamine results in increased expression of FAM160A2 mRNA | increases expression | 17616710 |
| C006253 | pirinixic acid | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of FAM160A2 mRNA | affects binding|decreases expression|increases activity | 19710929 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 3.64 | 18653653 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 4.22 | 16434500 | |
| MESH:D000799 | Angioedema | Acetaminophen | 4.71 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 3.63 | 19483382 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.81 | 10977129 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 3.15 | 19176532 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 2.59 | 18249437 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 11739529 19739265 16485898 19085960 11743745 12540782 19420014 17522070 18713872 16781746 10663392 11287661 19164858 17906064 16393943 14550746 11529661 11421492 12594235 11834606 17562736 16177239 19923254 19416960 2444490 18071297 19370779 12958197 12392966 14725611 10774834 12153990 16109766 12705907 16081117 10915739 15619225 16227642 15968718 11461765 14986274 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.96 | 19426721 | |
| MESH:D004487 | Edema | pirinixic acid | 2.96 | 12083418 | |
| MESH:D004938 | Esophageal Neoplasms | nitrosobenzylmethylamine | 2.86 | 15150132 16805852 15878914 16704527 16510608 15547721 15264214 15623463 15547733 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 3.25 | 20131406 19236843 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.54 | 16983495 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 2.78 | 20558911 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 3.64 | 18467677 16221962 19772884 19176532 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.06 | 16870215 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 3.63 | 20558911 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 2.90 | 16306350 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.42 | 12587719 15629191 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 1.35 | 15474484 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 16610002 19460945 16611625 19784758 11587558 12969438 12587719 19014921 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.68 | 16871587 17185352 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 1.94 | 15890375 20007298 16377806 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.22 | 19513568 | |
| MESH:D009135 | Muscular Diseases | pirinixic acid | 4.16 | 16239165 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 2.29 | 19151258 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 3.29 | 16411023 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 2.12 | 17405874 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.26 | 18514411 | |
| MESH:D009765 | Obesity | pirinixic acid | 1.89 | 20558911 | |
| MESH:D010146 | Pain | Acetaminophen | 2.77 | 16870215 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 2.56 | 19058328 | |
| MESH:D013274 | Stomach Neoplasms | nitrosobenzylmethylamine | 2.33 | 12958204 17575124 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.50 | 10982225 |
| No data |